N-(3-Oxooctanoyl)-DL-homoserine lacton is a member of N-Acyl homoserine lactone (AHL) from gram-negative bacteria, with stereochemistry-dependent growth regulatory activity for roots [1].
(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
((2,6-Difluorophenyl)sulfonyl)phenylalanine is a phenylalanine derivative[1].
Laminaribiose is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Dansyl-Ala-Arg is a synthetic peptide. Dansyl-Ala-Arg can be used for various biochemical studies[1].
TCO-PEG3-maleimide (TCO-PEG3-NEM) is a click chemistry reagent. TCO-PEG3-maleimide efficiently binds TCO (trans-cyclooctene) moiety to thiol-containing molecules (such as antibodies, cysteine-containing peptides)[1].
CME-carbodiimide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
(R)-2-((Methoxycarbonyl)amino)-2-phenylacetic acid is a Glycine (HY-Y0966) derivative[1].
Fosthiazate is a broad-spectrum nematicide against various plant parasitic nematodes, including Meloidogyne spp., Globodera spp., and Pratylenchus spp., through inhibiting the synthesis of acetylcholinesterase[1].
Piperitol is a compound isolated from the Tibetan medicinal plant Lancea tibetica[1].
Boc-L-Leu-OH is a leucine derivative[1].
Influenza virus NP (266-274) is a biological active peptide. (HLA-A*03 restricted epitope from influenza virus nucleoprotein (265-274).)
20-Deoxyingenol is a natural compound.
Hydroxyethyl starch is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Bisphenol Z-d6is the deuterium labeled4,4'-(Cyclohexane-1,1-diyl)diphenol(HY-W013326)[1].
D-Lyxose-13C-3 is the 13C labeled D-Lyxose. D-Lyxose is an endogenous metabolite[1].
17:0-18:1 PE-d5 is deuterium labeled 17:0-18:1 PE.
Kaempferol-7,4'-dimethyl ether is found in Boesenbergia longiflora[1].
Z-Phe-OBzl is a phenylalanine derivative[1].
3-Deaza-4’-C-methyluridine, 4-Hydroxy-1-β-D-(4-C-methylribofuranosyl)-2(1H)-pyridinone is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
O-Linked GlcNAc transferase substrate is a biological active peptide. (A peptide substrate of O-linked GlcNAc transferase (OGT), a eukaryotic glycosyltransferase that uses UDP-GlcNAc as a glycosyl donor.)
o-Toluidine-d7 is a deuterated labeled o-Toluidine (HY-41497). o-Toluidine is widely used to measure glucose levels in blood and body fluids. Glucose and primary aromatic amines can condense in glacial acetic acid to form an equilibrium mixture of sugar amines and corresponding Schiff bases. For example, use glacial acetic acid to prepare 6% o-Toluidine, add it to the solution containing the test, and add trichloroacetic acid to remove protein. After heating at 100°C for 10 minutes and rapidly cooling to room temperature, the absorbance at 630 nm can be measured to calculate the glucose level.
L-Isoleucine-1-13C is the 13C-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid.
D-Lactate dehydrogenase (D-LDH) is an oxidoreductase that uses NAD+ or NADP+ as an acceptor and acts on the donor CH-OH group, and can catalyze the oxidation of D-lactate to pyruvate. D-Lactate dehydrogenase widely exists in bacteria and fungi, and is often used in biochemical research[1].
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-cyanophenyl)propanoic acid is a phenylalanine derivative[1].
N-Acetyl-S-(4-nitrophenyl)-L-cysteine is a cysteine derivative[1].
Ibandronic acid is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.Target: OthersIbandronate (1.25-2 μM) significantly reduces endothelial cell growth, while ibandronate (2 μM) also significantly reduces capillary-like tube formation and increases apoptosis of endothelial cells. Ibandronate (< 100 μM) dose-dependently increases VEGF expression in endothelial cells [1]. Ibandronate (< 100 μM) inhibits growth of both prostate cancer cell lines (LNCaP and PC-3) in a dose dependent manner [2].Ibandronate administered either daily (2.5 mg) or intermittently (20 mg every other day for 12 doses every 3 months) significantly reduces the risk of new morphometric vertebral fractures by 62% and 50% (p = 0.0006), respectively, in osteoporotic women after 3 years' treatment. Ibandronate administered either daily (2.5 mg) or intermittently (20 mg every other day for 12 doses every 3 months) significantly and progressively increases BMD of lumbar spine by 6.5% and 5.7%, respectively, in osteoporotic women after 3 years' treatment [3]. Ibandronate (< 125 mg/kg s.c.) results in a dose dependent increase in bone mineral density (BMD), trabecular bone volume and trabecular number, load to failure (Fmax), and yield load in long bones and vertebrae in ovariectomized rats, and increased trabecular separation in ovariectomized rats is fully prevented by all doses [4].
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone-3-O-α-rhamnosyl-(1→2)-β-D-glucoside is a natural product that can be isolated from the roots of Rubia cordifolia[1].
K02288 is a potent inhibitor of ALK, and inhibits ALK1/2/3/6 with IC50s of 1.8/1.1/34.4/6.3 nM; K02288 is less potent against ALK4/5, with IC50s of 302 nM and 321 nM.
Fmoc-Met-OH is a Methionine (HY-13694) derivative[1].