68408-22-0

68408-22-0 structure

Name: 2-Toluidine-d7
Chemical Name: 2,3,4,5-tetradeuterio-6-trideuteriomethyl-aniline
CAS Number: 68408-22-0
Molecular Formula: C₇H₂D₇N
Molecular Weight: 114.19600
Catalog: Research Areas Others
Create Date: 2018-06-20 18:11:34
Modify Date: 2024-04-03 12:48:31
o-Toluidine-d7 is a deuterated labeled o-Toluidine (HY-41497). o-Toluidine is widely used to measure glucose levels in blood and body fluids. Glucose and primary aromatic amines can condense in glacial acetic acid to form an equilibrium mixture of sugar amines and corresponding Schiff bases. For example, use glacial acetic acid to prepare 6% o-Toluidine, add it to the solution containing the test, and add trichloroacetic acid to remove protein. After heating at 100°C for 10 minutes and rapidly cooling to room temperature, the absorbance at 630 nm can be measured to calculate the glucose level.

Name	2,3,4,5-tetradeuterio-6-trideuteriomethyl-aniline
Synonyms	2-Toluidine-d7

Description	o-Toluidine-d7 is a deuterated labeled o-Toluidine (HY-41497). o-Toluidine is widely used to measure glucose levels in blood and body fluids. Glucose and primary aromatic amines can condense in glacial acetic acid to form an equilibrium mixture of sugar amines and corresponding Schiff bases. For example, use glacial acetic acid to prepare 6% o-Toluidine, add it to the solution containing the test, and add trichloroacetic acid to remove protein. After heating at 100°C for 10 minutes and rapidly cooling to room temperature, the absorbance at 630 nm can be measured to calculate the glucose level.
Related Catalog	Research Areas >> Others
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.