Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

1,N6-Ethenoadenosine 5'-monophosphate sodium

1,N6-Ethenoadenosine 5'-monophosphate (1,N6-Etheno-AMP) sodium is a highly fluorescent analog of adenosine 5'-monophosphate (AMP). 1,N6-Ethenoadenosine 5'-monophosphate sodium is a powerful probe for systems involving adenosine 5'-monophosphate and can be detected at low concentration. 1,N6-Ethenoadenosine 5'-monophosphate sodium has long wavelength of excitation (250-300 nm), and emission at 415 nm[1][2].

  • CAS Number: 885597-18-2
  • MF: C12H12N5Na2O7P
  • MW: 415.21
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

S-Adenosyl-L-methionine disulfate tosylate

S-Adenosyl-L-methionine disulfate tosylate is the principal biological methyl donor synthesized in all mammalian cells but most abundantly in the liver.

  • CAS Number: 97540-22-2
  • MF: C22H34N6O16S4
  • MW: 766.796
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LYS-VAL HYDROCHLORIDE

(S)-2-((S)-2,6-Diaminohexanamido)-3-methylbutanoic acid hydrochloride is a valine derivative[1].

  • CAS Number: 92218-55-8
  • MF: C11H24ClN3O3
  • MW: 281.78000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Cys(Trt)-OH

Fmoc-Cys(Trt)-OH is a cysteine derivative[1].

  • CAS Number: 103213-32-7
  • MF: C37H31NO4S
  • MW: 585.711
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 763.4±60.0 °C at 760 mmHg
  • Melting Point: 170-173 °C(lit.)
  • Flash Point: 415.5±32.9 °C

GPI-1046

GPI-1046 is a immunophilin ligand without antibiotic action and attenuates ethanol intake in part through the upregulation of glutamate transporter 1 (GLT1) in PFC and NAc-core. GPI-1046 is an analog of FK506, which is an immunophilin ligand that has been shown neuroprotective effects in neurodegenerative disease models[1]. GPI-1046 readily crosses the blood-brain barrier and promotes the regeneration of dopamine (DA) cells in the CNS in association with functional recovery in rodent models[2].

  • CAS Number: 186452-09-5
  • MF: C20H28N2O4
  • MW: 360.447
  • Catalog: Neurological Disease
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 501.5±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 257.1±32.9 °C

INO5042

INO5042 is an anti-inflammatory agent.

  • CAS Number: 14782-19-5
  • MF: C15H7NO3S
  • MW: 281.286
  • Catalog: Inflammation/Immunology
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 504.1±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 258.7±27.9 °C

cyclandelate

Cyclandelate is a vasodilator used in the treatment of claudication, arteriosclerosis, and Raynaud's disease. It is also used to treat nighttime leg cramps, and has been investigated for its effect against migraine.

  • CAS Number: 456-59-7
  • MF: C17H24O3
  • MW: 276.371
  • Catalog: Cardiovascular Disease
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 380.1±22.0 °C at 760 mmHg
  • Melting Point: 55.0-56.5°
  • Flash Point: 150.1±15.1 °C

Boc-L-3-Thienylalanine.DCHA

Boc-β-(3-thienyl)-Ala-OH (dicyclohexylammonium) salt is an alanine derivative[1].

  • CAS Number: 331730-13-3
  • MF: C24H40N2O4S
  • MW: 452.650
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-O-Acetyl-16 alpha-hydroxytrametenolic acid

3-O-Acetyl-16α-hydroxytrametenolic acid (Compound 3) is a triterpene found in Poria cocos, with anti-oxidant and anti-cancer activity[1].

  • CAS Number: 168293-13-8
  • MF: C32H50O5
  • MW: 514.736
  • Catalog: Cancer
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 606.9±55.0 °C at 760 mmHg
  • Melting Point: >300 °C
  • Flash Point: 185.1±25.0 °C

3-Mercapto-3-methylbutan-1-ol-d6

3-Mercapto-3-methylbutan-1-ol-d6 is the deuterium labeled Hypoxanthine. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.

  • CAS Number: 162404-35-5
  • MF: C5H6D6OS
  • MW: 126.25
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 190.1±23.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 68.8±22.6 °C

H-Arg-Gly-Asp-Cys-OH trifluoroacetate salt

Arg-Gly-Asp-Cys is the binding motif of fibronectin to cell adhesion molecules, and can inhibit platelet aggregation and fibrinogen binding.

  • CAS Number: 109292-46-8
  • MF: C15H27N7O7S
  • MW: 449.48300
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(+)-Totaradiol

Totaradiol ((+)-Totaradiol; 3β-Hydroxytotarol) is a diterpene can be isolated from Thuja plicata (Cupressaceae)[1].

  • CAS Number: 3772-56-3
  • MF: C20H30O2
  • MW: 302.451
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 407.5±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 179.0±23.3 °C

1,1-Dibromo-3-chloroacetone

1,1-Dibromo-3-chloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant[1].

  • CAS Number: 1578-18-3
  • MF: C3H3Br2ClO
  • MW: 250.316
  • Catalog: Others
  • Density: 2.2±0.1 g/cm3
  • Boiling Point: 236.0±25.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 96.5±23.2 °C

3-(4-((Bis((1-(tert-butyl)-1H-1,2,3-triazol-4-yl)methyl)amino)methyl)-1H-1,2,3-triazol-1-yl)propan-1-ol

BTTP is a tris(triazolylmethyl)amine-based ligand. BTTP can accelerate the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC), the prototypical reaction in click chemistry[1].

  • CAS Number: 1341215-17-5
  • MF: C20H34N10O
  • MW: 430.55
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-hydroxycoumarin

3-hydroxycoumarin is a potent and redox inhibitor of human 15-LOX-1. 3-hydroxycoumarin is recently demonstrated to protect sea urchin reproductive cells against ultraviolet B damage[1][2].

  • CAS Number: 939-19-5
  • MF: C9H6O3
  • MW: 162.14200
  • Catalog: Others
  • Density: 1.446 g/cm3
  • Boiling Point: 369.9ºC at 760 mmHg
  • Melting Point: 153-157 °C(lit.)
  • Flash Point: 174.7ºC

Dimethocaine

Dimethocaine is a local anesthetic with reported stimulant properties most similar to cocaine.

  • CAS Number: 94-15-5
  • MF: C16H26N2O2
  • MW: 278.390
  • Catalog: Apoptosis
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 403.5±25.0 °C at 760 mmHg
  • Melting Point: 53.0 to 57.0 deg-C
  • Flash Point: 197.8±23.2 °C

Lumiliximab

Lumiliximab (Anti-CD23 Recombinant Antibody) is an anti-CD23 monoclonal antibody that inhibits allergen-induced responses[1].

  • CAS Number: 357613-86-6
  • MF:
  • MW: 47.75 (kDa)
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

beta-D-Glucopyranoside, 3,9-dihydroxy-16,17-dimethoxytricyclo(12.3.1.1 (2,6))nonadeca-1(18),2,4,6(19),14,16-hexaen-15-yl, (R)-

5-O-beta-D-Glucopyranosylmyricanol is a diarylheptane compound isolated from Myrica esculenta that has a weak inhibitory effect on angiotensin-converting enzyme (ACE)[1].

  • CAS Number: 90052-02-1
  • MF: C27H36O10
  • MW: 520.56900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Baccatin III

Baccatin III is a natural product isolated from Pacific yew tree and related species. Baccatin III reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs[1].

  • CAS Number: 27548-93-2
  • MF: C31H38O11
  • MW: 586.627
  • Catalog: Cancer
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 713.6±60.0 °C at 760 mmHg
  • Melting Point: 229-234 °C
  • Flash Point: 226.9±26.4 °C

prostaglandin D2(PGD2) inhibitor

PGD2-IN-1 is an antagonist of DP extracted from patent WO 2006044732 A2, example 15 (d); has an IC50 of 0.3 nM.

  • CAS Number: 885066-67-1
  • MF: C23H23Cl2N3O3
  • MW: 460.353
  • Catalog: Inflammation/Immunology
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 682.1±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 366.3±34.3 °C

C13-113-tri-tail

C13-113-tri tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a tertiary amine linker. C13-113-tri tail can be formulated into a lipid nanoparticle (LNP).

  • CAS Number: 1381861-86-4
  • MF: C44H93N3O3
  • MW: 712.23
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tetramethylammonium-d12 chloride

Tetramethylammonium-d12 (chloride) is the deuterium labeled Tetramethylammonium chloride[1].

  • CAS Number: 23789-03-9
  • MF: C4ClD12N
  • MW: 121.67200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: >300ºC
  • Flash Point: N/A

C80-1324

C80-1324 is a furoxan compound. C80-1324 reveals marked dilator activity in the coronary circulation of isolated working hearts.

  • CAS Number: 83656-38-6
  • MF: C10H16N4O4
  • MW: 256.25800
  • Catalog: Cardiovascular Disease
  • Density: 1.38g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ricinoleic acid

Ricinoleic acid, from castor (Ricinus communis) seed oil, is a high-value hydroxy fatty acid with broad industrial applications. Ricinoleic acid is an attractive feedstock for the production of high-performance lubricants, cosmetics, polymers, surfactants, and coatings[1].

  • CAS Number: 141-22-0
  • MF: C18H34O3
  • MW: 298.461
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 416.4±20.0 °C at 760 mmHg
  • Melting Point: 〈10ºC
  • Flash Point: 219.8±18.3 °C

quizalofop-P-ethyl

Quizalofop-P-ethyl is a slightly toxic, selective, postemergence phenoxy herbicide, used to control annual and perennial grass weeds in potatoes, soybeans, sugar beets, peanuts vegetables, cotton and flax. Quizalofop-P-ethyl is absorbed from the leaf surface and is moved throughout the plant. Quizalofop-P-ethyl accumulates in the active growing regions of stems and roots.

  • CAS Number: 100646-51-3
  • MF: C19H17ClN2O4
  • MW: 372.802
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 503.9±50.0 °C at 760 mmHg
  • Melting Point: 76-77°C
  • Flash Point: 258.6±30.1 °C

Methyl N-methylglycinate hydrochloride

Methyl N-methylglycinate hydrochloride is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 13515-93-0
  • MF: C4H10ClNO2
  • MW: 139.581
  • Catalog: Others
  • Density: 0.964g/cm3
  • Boiling Point: 118.9ºC at 760 mmHg
  • Melting Point: 117-119 °C(lit.)
  • Flash Point: 25.7ºC

Grandifloroside

Grandifloroside is a natural product that can be found in Anthocleista grandiflora[1].

  • CAS Number: 61186-24-1
  • MF: C25H30O13
  • MW: 538.50
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 801.8±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 268.2±27.8 °C

SB 268262

CGRP antagonist 4 is an antagonist of calcitonin gene-related peptide (CGRP) receptor. CGRP antagonist 4 shows the highest affinity for CGRP receptors in the human brain. CGRP antagonist 4 can be used to study the binding properties of non-peptide calcitonin gene-related peptide (CGRP) receptor antagonist (gepants) in rat, pig and human menes [1].

  • CAS Number: 217438-17-0
  • MF: C18H15N3O4S2
  • MW: 401.46
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-one

(12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-one is a natural product that can be found in Cladosporium microorganisms[1].

  • CAS Number: 1123845-41-9
  • MF: C36H60O8
  • MW: 620.86
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Dichotomine H

Dichotomine H is a P-carboline alkaloid that can be extracted from Stellaria dichotoma L. Dichotomine H has good antiallergic activity[1].

  • CAS Number: 1384373-52-7
  • MF: C19H17N3O6
  • MW: 383.35
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A