SB 268262

Modify Date: 2025-08-27 00:44:18

SB 268262 Structure
SB 268262 structure
 Common Name SB 268262
CAS Number 217438-17-0 Molecular Weight 401.46
Density N/A Boiling Point N/A
Molecular Formula C18H15N3O4S2 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07		 Signal Word Warning

 Use of SB 268262


CGRP antagonist 4 is an antagonist of calcitonin gene-related peptide (CGRP) receptor. CGRP antagonist 4 shows the highest affinity for CGRP receptors in the human brain. CGRP antagonist 4 can be used to study the binding properties of non-peptide calcitonin gene-related peptide (CGRP) receptor antagonist (gepants) in rat, pig and human menes [1].

 Names

Name N-Methyl-N-(2-methylphenyl)-3-nitro-4-(1,3-thiazol-2-ylsulfinyl)b enzamide
Synonym More Synonyms

 SB 268262 Biological Activity

Description CGRP antagonist 4 is an antagonist of calcitonin gene-related peptide (CGRP) receptor. CGRP antagonist 4 shows the highest affinity for CGRP receptors in the human brain. CGRP antagonist 4 can be used to study the binding properties of non-peptide calcitonin gene-related peptide (CGRP) receptor antagonist (gepants) in rat, pig and human menes [1].
Related Catalog
References

[1]. Warfvinge K, et al. The Presence of Calcitonin Gene-Related Peptide and Its Receptors in Rat, Pig and Human Brain: Species Differences in Calcitonin Gene-Related Peptide Pharmacology. Pharmacology. 2019;104(5-6):332-341.  

 Chemical & Physical Properties

Molecular Formula C18H15N3O4S2
Molecular Weight 401.46
Exact Mass 401.05000
PSA 143.54000
LogP 5.19190

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H319
Precautionary Statements P305 + P351 + P338
RIDADR NONH for all modes of transport

 Synonyms

(+/-)-SB-273779 N-Methyl-N-(2-methylphenyl)-3-nitro-4-(2-thiazolylsulfinyl)-benzamide
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Chemsrc provides SB 268262(CAS#:217438-17-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of SB 268262 are included as well.>> amp version: SB 268262

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