Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Dimethocaine
Price: ￥558.0/1g
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Dimethocaine
Price: $150.0/100mg $300.0/250mg $600.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Zhejiang Hangyu API Co., Ltd
China
Product Name: Larocaine
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Larocaine
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

94-15-5

94-15-5 structure

94-15-5 structure

Name: Dimethocaine
Chemical Name: 1-Propanol, 2-[(diethylamino)methyl]-2-methyl-, 1-(4-aminobenzoate)
CAS Number: 94-15-5
Molecular Formula: C₁₆H₂₆N₂O₂
Molecular Weight: 278.390
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-08-08 17:38:55
Modify Date: 2024-01-02 16:21:24
Dimethocaine is a local anesthetic with reported stimulant properties most similar to cocaine.

Name	1-Propanol, 2-[(diethylamino)methyl]-2-methyl-, 1-(4-aminobenzoate)
Synonyms	Larocaine 1-Propanol, 3-(diethylamino)-2,2-dimethyl-, p-aminobenzoate (ester) (8CI) 1-Propanol, 3-(diethylamino)-2,2-dimethyl-, 4-aminobenzoate (ester) 1-Aminobenzoyl-2,2-dimethyl-3-diethylaminopropanol 3-(Diethylamino)-2,2-dimethyl-1-propanol p-Aminobenzoate 3-(Diethylamino)-2,2-dimethylpropyl 4-aminobenzoate p-Aminobenzoate of Diethylaminoneopentyl Alcohol 3-Diethylamino-2,2-dimethylpropyl p-Aminobenzoate Dimethocaine 1-Propanol, 3- (diethylamino)-2,2-dimethyl-, p-aminobenzoate (ester) DiMethocine 1-Propanol, 3-(diethylamino)-2,2-dimethyl-, 4-aminobenzoate (ester) (9CI) 1-Propanol, 3- (diethylamino)-2,2-dimethyl-, 4-aminobenzoate (ester) 3-Diethylamino-2,2-dimethylpropyl 4-aminobenzoate

Description	Dimethocaine is a local anesthetic with reported stimulant properties most similar to cocaine.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Rigon AR, et al. Stimulant activities of dimethocaine in mice: reinforcing and anxiogenic effects. Psychopharmacology (Berl). 1996 Oct;127(4):323-7.

Density	1.0±0.1 g/cm3
Boiling Point	403.5±25.0 °C at 760 mmHg
Melting Point	53.0 to 57.0 deg-C
Molecular Formula	C₁₆H₂₆N₂O₂
Molecular Weight	278.390
Flash Point	197.8±23.2 °C
Exact Mass	278.199432
PSA	55.56000
LogP	3.55
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.529

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UB1575000

CHEMICAL NAME :: 1-Propanol, 3-(diethylamino)-2,2-dimethyl-, p-aminobenzoate

CAS REGISTRY NUMBER :: 94-15-5

BEILSTEIN REFERENCE NO. :: 2215967

LAST UPDATED :: 199712

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C16-H26-N2-O2

MOLECULAR WEIGHT :: 278.44

WISWESSER LINE NOTATION :: ZR DVO1X1&1&1N2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 380 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Cardiac - other changes Lungs, Thorax, or Respiration - other changes

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 168,447,1932

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 12,190,1932

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 12,190,1932

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 12,190,1932

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 12,190,1932

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 860 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation Lungs, Thorax, or Respiration - other changes

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 168,447,1932 *** REVIEWS *** TOXICOLOGY REVIEW PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 12,190,1932

HS Code	2942000000

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%