Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

R-(-)-Oxaprotiline hydrochloride

R-(-)-Oxaprotiline (Levoprotiline) hydrochloride is the R-enantiomer of Oxaprotiline. Oxaprotiline is a tetracyclic antidepressant agent[1].

  • CAS Number: 76496-69-0
  • MF: C20H24ClNO
  • MW: 329.86
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(3S,5S)-1,7-Bis(4-hydroxyphenyl)-3,5-heptanediol

Hannokinol is a potent anti-tumor agent. Hannokinol shows antiproliferative activity. Hannokinol shows antioxidant activities[1].

  • CAS Number: 79120-40-4
  • MF: C19H24O4
  • MW: 316.39
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 570.2±50.0 °C at 760 mmHg
  • Melting Point: 156-158℃ (methanol )
  • Flash Point: 266.9±24.7 °C

Anhydroepiophiobolin A

Anhydro-6-epiophiobolin A, an analog of Ophiobolin A, is a potent inhibitor of photosynthesis (I50s of 6.1 and 1 mM for photosynthesis in Chlorella and Spinach, respectively)[1].

  • CAS Number: 90411-20-4
  • MF: C25H34O3
  • MW: 382.53600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fosdenopterin hydrobromide dihydrate

Fosdenopterin (Precursor Z) hydrobromide dehydrate is a synthetic cyclic pyranopterin monophosphate (cPMP). Fosdenopterin hydrobromide dihydrate can be used for the research of molybdenum cofactor deficiency (MoCD) type A[1].

  • CAS Number: 2301083-34-9
  • MF: C10H19BrN5O10P
  • MW: 480.16
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cnidioside B Methyl ester

Cnidioside B methyl ester is a glucoside compound,which can be isolated from Ami mjus L[1].

  • CAS Number: 158500-59-5
  • MF: C19H24O10
  • MW: 412.39
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 603.5±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 318.8±31.5 °C

UNII:CC64495H41

7-Hydroxyflavanone is an aromatase (cytochrome P450 19; CYP19) inhibitor with an IC50 of 65 μM[1].

  • CAS Number: 6515-36-2
  • MF: C15H12O3
  • MW: 240.254
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 464.3±45.0 °C at 760 mmHg
  • Melting Point: 188-190 °C(lit.)
  • Flash Point: 181.2±22.2 °C

Rhodamine 6G

Rhodamine 6G is a rhodamine analog useful in Pgp efflux assays. It can be used in characterizing the kinetics of MRP1- mediated efflux, and as a laser dye and potential mitochondrial probe.

  • CAS Number: 989-38-8
  • MF: C28H31ClN2O3
  • MW: 479.010
  • Catalog: Dye Reagents
  • Density: 1.15g/cm3
  • Boiling Point: <200ºC
  • Melting Point: 290 °C
  • Flash Point: 318.6ºC

Bzl-ser-oh

Benzyl-L-serine is a serine derivative[1].

  • CAS Number: 17136-45-7
  • MF: C10H13NO3
  • MW: 195.215
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 405.6±40.0 °C at 760 mmHg
  • Melting Point: 223-225?C
  • Flash Point: 199.1±27.3 °C

microstegiol

Microstegiol is a diterpene that can be isolated from Salvia microstegia and the root of Zhumeria majdae[1].

  • CAS Number: 143246-41-7
  • MF: C20H26O2
  • MW: 298.41900
  • Catalog: Others
  • Density: 1.097±0.06 g/cm3
  • Boiling Point: 433.3±45.0 °C at 760 mmHg
  • Melting Point: 70 °C
  • Flash Point: N/A

Boc-D-4-iodophenylalanine

Boc-D-Phe(4-I)-OH is a phenylalanine derivative[1].

  • CAS Number: 176199-35-2
  • MF: C14H18INO4
  • MW: 391.202
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 475.3±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 241.3±27.3 °C

FM1-43

FM1-43, a styryl dye used to study endocytosis and exocytosis, behaves as a permeant blocker of the hair-cell mechanotransducer channel. FM1-43 also reduces the ototoxic effects of the aminoglycoside antibiotic neomycin sulfate[1].

  • CAS Number: 149838-22-2
  • MF: C30H49Br2N3
  • MW: 611.53800
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Guanosine 5'-triphosphate (GTP), ammonium salt-d27

Guanosine 5'-triphosphate (GTP), ammonium salt-d27 is the deuterium labeled Guanosine 5'-triphosphate (GTP), ammonium salt[1].

  • CAS Number: 2483831-68-9
  • MF: C10D28N9O14P3
  • MW: 619.48
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Neuronostatin-13 (human, canine, porcine) trifluoroacetate salt

Neuronostatin-13 human is a 13-amino acid peptide hormone encoded by the somatostatin gene and plays an important role in the regulation of hormonal and cardiac function.

  • CAS Number: 1096485-24-3
  • MF: C64H110N20O16
  • MW: 1415.68000
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5,6-trans-Travoprost

5,6-trans-Travoprost is the inactive isomer of Travoprost (HY-B0584), and can be used as an experimental control. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension[1].

  • CAS Number: 1563176-59-9
  • MF: C26H35F3O6
  • MW: 500.55
  • Catalog: Endocrinology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 584.8±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 307.5±30.1 °C

N,N'-bis(1,3-benzodioxol-5-yl)ethanediamide

WAY-621089 is an active molecule for the study of amyloid diseases and synucleinopathies[1].

  • CAS Number: 303790-92-3
  • MF: C16H12N2O6
  • MW: 328.276
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Dexivacaine

(+)-Mepivacaine is a racemic isomer of Mepivacaine (HY-B0517), which has analgesic and vasoconstrictive activity. Mepivacaine is an amide type agent that temporarily causes local loss of consciousness. Mepivacaine binds to specific voltage-gated sodium channels on neuronal cell membranes, inhibiting sodium influx and membrane depolarization[1].

  • CAS Number: 24358-84-7
  • MF: C15H22N2O
  • MW: 246.35
  • Catalog: Cardiovascular Disease
  • Density: 1.077g/cm3
  • Boiling Point: 383.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 185.5ºC

7-Xylosyl-10-deacetyltaxol B

7-Xylosyl-10-Deacetyltaxol B (7-xylosyl-10-Deacetylpaclitaxel B) is a paclitaxel derivative derived from T. cuspidate. 7-Xylosyl-10-Deacetyltaxol B has anti-tumor activity and inhibits the growth of S180 sarcoma[1].

  • CAS Number: 90332-64-2
  • MF: C48H59NO17
  • MW: 921.97900
  • Catalog: Cancer
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 1041.3±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 583.5±34.3 °C

3'-Methoxyflavonol

3'-Methoxyflavonol is a selective agonist of neuromedin U 2 receptor (NMU2R).

  • CAS Number: 76666-32-5
  • MF: C16H12O4
  • MW: 268.26400
  • Catalog: Neurological Disease
  • Density: 1.353g/cm3
  • Boiling Point: 435.2ºC at 760 mmHg
  • Melting Point: 130-131ºC
  • Flash Point: 164.4ºC

Anaprel

Rescinnamine is a derivative of the indole alkaloid reserpine. Rescinnamine shows sedative effects. Rescinnamine can be used for hypertension research[1][2].

  • CAS Number: 24815-24-5
  • MF: C35H42N2O9
  • MW: 634.71600
  • Catalog: Metabolic Disease
  • Density: 1.31g/cm3
  • Boiling Point: 756.8ºC at 760 mmHg
  • Melting Point: 238ºC
  • Flash Point: 411.5ºC

Macrostemonoside I

Macrostemonoside I is a furostanol saponin that can be isolated from Allium macrostemon[1].

  • CAS Number: 162413-63-0
  • MF: C45H72O20
  • MW: 933.04
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Oxo Ibuprofen

1-Oxo Ibuprofen (Ibuprofen EP impurity J) is a degradation product and a potential impurity in preparations of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1][2].

  • CAS Number: 65813-55-0
  • MF: C13H16O3
  • MW: 220.26400
  • Catalog: Others
  • Density: 1.107g/cm3
  • Boiling Point: 377.952ºC at 760 mmHg
  • Melting Point: 85-87ºC
  • Flash Point: 196.555ºC

4-Nitrobenzoic acid-d4

4-Nitrobenzoic acid-d4 is the deuterium labeled 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine fumarate  (Vonoprazan Impurity)[1].

  • CAS Number: 171777-66-5
  • MF: C7HD4NO4
  • MW: 171.14
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Dibenzylamine-d10

Dibenzylamine-d10 is the deuterium labeled Dibenzylamine[1].

  • CAS Number: 923282-09-1
  • MF: C14H15N
  • MW: 197.27600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Iota-conotoxin RXIA

lota-conotoxin RXIA is an agonist of voltage-gatedsodium channels (Nav1.2, 1.6, 1.7). Iota-conotoxin RXIAcan induce repetitive action potential and seizure in motor axons of frogsafter intracranial injection in mice [1].

  • CAS Number: 1042682-52-9
  • MF: C212H310N54O69S8
  • MW: 4975.57
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(3β,22E,24S)-Stigmasta-5,22,25-trien-3-ol

22-Dehydroclerosterol is a compound that can be found in Morinda citrifolia L.[1].

  • CAS Number: 26315-07-1
  • MF: C29H46O
  • MW: 410.67
  • Catalog: Inflammation/Immunology
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 505.4±19.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 219.9±13.7 °C

1,2-Dipalmitoyl-3-oleoylglycerol

1,2-Dipalmitoyl-3-oleoylglycerol, a major P-containing triacylglycerol, can be found in palm oil, palm stearin, cocoa butter, and lard[1].

  • CAS Number: 1867-91-0
  • MF: C53H100O6
  • MW: 833.35700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Loureiriol

Loureiriol is a homoisoflavonoid with weak anticancer effects[1].

  • CAS Number: 479195-44-3
  • MF: C16H14O6
  • MW: 302.28
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Glycerol phenylbutyrate

Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand, with a pKi of 8.02.

  • CAS Number: 611168-24-2
  • MF: C33H38O6
  • MW: 530.65100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Mequinol

Mequinol (4-Methoxyphenol) is one of bioactive components in Mercurialis spp. Mequinol is used for skin depigmentation[1]

  • CAS Number: 150-76-5
  • MF: C7H8O2
  • MW: 124.137
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 243.0±0.0 °C at 760 mmHg
  • Melting Point: 56 °C
  • Flash Point: 120.8±4.8 °C

Riboflavin-5-phosphate sodium

Riboflavin phosphate sodium significantly increases in corneal biomechanical stiffness

  • CAS Number: 130-40-5
  • MF: C17H20N4NaO9P
  • MW: 478.326
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: >300°C
  • Flash Point: N/A