5,6-trans-Travoprost

Modify Date: 2024-01-14 19:25:36

5,6-trans-Travoprost Structure
5,6-trans-Travoprost structure
Common Name 5,6-trans-Travoprost
CAS Number 1563176-59-9 Molecular Weight 500.55
Density 1.2±0.1 g/cm3 Boiling Point 584.8±50.0 °C at 760 mmHg
Molecular Formula C26H35F3O6 Melting Point N/A
MSDS N/A Flash Point 307.5±30.1 °C

 Use of 5,6-trans-Travoprost


5,6-trans-Travoprost is the inactive isomer of Travoprost (HY-B0584), and can be used as an experimental control. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension[1].

 Names

Name Isopropyl (5E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl}cyclopentyl]-5-heptenoate
Synonym More Synonyms

 5,6-trans-Travoprost Biological Activity

Description 5,6-trans-Travoprost is the inactive isomer of Travoprost (HY-B0584), and can be used as an experimental control. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension[1].
Related Catalog
References

[1]. M R Hellberg, et al. Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist. J Ocul Pharmacol Ther. 2001 Oct;17(5):421-32.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 584.8±50.0 °C at 760 mmHg
Molecular Formula C26H35F3O6
Molecular Weight 500.55
Flash Point 307.5±30.1 °C
Exact Mass 500.238586
LogP 3.98
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.547

 Synonyms

Isopropyl (5E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl}cyclopentyl]-5-heptenoate
5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5E)-
Isopropyl (5E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl]hept-5-enoate
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