Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Dansyl-Tyr-Val-Gly TFA

Dansyl-Tyr-Val-Gly TFA is a substrate of peptidylglycine monooxygenase (PHM). Peptidylglycine monooxygenase is an essential enzyme for the posttranslational amidation of neuroendocrine peptides[1].

  • CAS Number: 350691-68-8
  • MF: C30H35F3N4O9S
  • MW: 684.68
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ajugalide D

Ajugalide D, a neoclerodane diterpene, is nature product that could be isolated from Ajuga taiwanensis[1].

  • CAS Number: 853247-65-1
  • MF: C21H32O6
  • MW: 380.475
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 544.0±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 185.8±19.4 °C

h-lys-lys-oh 2hcl

L-Lysyl-L-lysine (Lysyllysine) dihydrochloride is an enzyme cleavable basic amino acid. L-Lysyl-L-lysine dihydrochloride can be used for delivering multiple biologically active peptides[1].

  • CAS Number: 52123-30-5
  • MF: C12H28Cl2N4O3
  • MW: 347.28200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Huzhangoside C

Huzhangoside C is a oleanane-type triterpenoid saponin that can be isolated from the roots of Clematis argentilucida[1].

  • CAS Number: 96315-52-5
  • MF: C64H104O29
  • MW: 1337.49
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Chymase-IN-1

Chymase-IN-1 is a potent, selective, orally active, nonpeptide inhibitor of human mast cell chymase with an IC50 of 29 nM.

  • CAS Number: 862090-74-2
  • MF: C20H15ClNO4PS
  • MW: 431.83
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

8(14)-Abietenic acid

8(14)-Abietenic acid is an abietane diterpenoid. Abietenic acid is racemic of 8(14)-Abietenic acid. Abietenic acid acts as a PPARα/γ dual activator[1][2].

  • CAS Number: 19407-37-5
  • MF: C20H32O2
  • MW: 304.467
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 421.8±34.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 202.3±20.3 °C

UNII:R99EE080JS

(S)-Lisofylline ((S)-Lisophylline)) is a kind of lisofline (LSF) enantiomer with optical activity. (S)-Lisofylline can interconversion with pentoxifylline[1][2].

  • CAS Number: 100324-80-9
  • MF: C13H20N4O3
  • MW: 280.323
  • Catalog: Inflammation/Immunology
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 511.2±56.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 263.0±31.8 °C

Physapruin A

Physapruin A is a withanolide that can be found in Physalis pruinosa[1].

  • CAS Number: 155178-03-3
  • MF: C28H38O7
  • MW: 486.60
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

NSC363998 free base

NSC363998 (free base) is an orally active compound. NSC363998 (free base) can suppress rCGG90 induced neurotoxicity. NSC363998 (free base) can be used for the research of neurodegenerative disorder such as Fragile X associated tremor/ataxia syndrome (FXTAS)[1].

  • CAS Number: 159357-82-1
  • MF: C24H32N4O4
  • MW: 440.54
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3,4,5-Trimethoxyphenyl-(6'-O-galloyl)-O-β-D-glucopyranoside

3,4,5-Trimethoxyphenyl-(6' -o-galloyl) -o-β-d-Glucopyranoside is a phenylpropanoside derived from natural the bark of Streblus ilicifolius (Vidal)[1].

  • CAS Number: 109206-94-2
  • MF: C22H26O13
  • MW: 498.43
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(D-Trp6)-LHRH-Leu-Arg-Pro-Gly amide

(D-Trp6)-LHRH-Leu-Arg-Pro-Gly amide is a biologically active peptide.

  • CAS Number: 1926163-16-7
  • MF: C83H115N25O17
  • MW: 1734.98
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Alloferon 2 trifluoroacetate salt

Alloferon 2 is an antiviral and antitumoral peptide. Alloferon 2 can be isolated from the blood of the blow fly Calliphora vicina (Diptera)[1].

  • CAS Number: 347884-62-2
  • MF: C46H68N19O15
  • MW: 1127.15000
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PA-9

PA-9 is a pituitary adenylate cyclase-activating polypeptide (PACAP) type I (PAC1) receptor antagonist. PA-9 dose dependently inhibits PACAP-induced cAMP elevation with an IC50 of 5.6 nM. PA-9 can be used for the research of neuropathic and/or inflammatory pain[1].

  • CAS Number: 1436004-46-4
  • MF: C17H18N6O2
  • MW: 338.36
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(D-Trp8)-Somatostatin-14 trifluoroacetate salt

[D-Trp8] Somatostatin-14, a tetradecapeptide, is an analog of Somatostatin more potent than the native Somatostatin[1].

  • CAS Number: 58976-46-8
  • MF: C76H104N18O19S2
  • MW: 1637.878
  • Catalog: Neurological Disease
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 1970.9±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 1145.7±34.3 °C

5'-DMT-2'-F-Bz-dA

DMT-2'-F-Bz-dA can be used in the synthesis of nucleotides and nucleic acids.

  • CAS Number: 136834-21-4
  • MF: C38H34FN5O6
  • MW: 675.70500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Phytochelatin 6

Phytochelatin 6 is metal-binding compound produced by plants. Phytochelatin 6 may reduce bioavailability of dietary toxic metals such as cadmium[1].

  • CAS Number: 99478-30-5
  • MF: C50H77N13O26S6
  • MW: 1468.61
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bimosiamose

Bimosiamose is a pan-selectin antagonist, inhibits E-, P-, and L-selectin with IC50s of 88 μM, 20 μM, and 86 μM, respectively, and can be used in the research of inflammatory disease.

  • CAS Number: 187269-40-5
  • MF: C46H54O16
  • MW: 862.911
  • Catalog: Inflammation/Immunology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 1051.0±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 309.7±27.8 °C

aceprometazine

Aceprometazine (1664CB) is an orally active antipsychotic. Aceprometazine can be used in the study of psychiatric disorders, such as depression[1].

  • CAS Number: 13461-01-3
  • MF: C19H22N2OS
  • MW: 326.456
  • Catalog: Neurological Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 490.1±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 250.2±28.7 °C

5(6)-TAMRA, SE [5-(and-6)-Carboxytetramethylrhodamine, succinimidyl ester]

5(6)-TAMRA SE is the amine-reactive, mixed isomer form of TAMRA, which is a dye for oligonucleotide labeling and automated DNA sequencing applications.

  • CAS Number: 246256-50-8
  • MF: C29H25N3O7
  • MW: 527.52500
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Gentisin

Gentisin is a natural compound isolated from Gentianae radix (Gentianaceae) with mutagenic activities[1].

  • CAS Number: 437-50-3
  • MF: C14H10O5
  • MW: 258.22600
  • Catalog: Others
  • Density: 1.48g/cm3
  • Boiling Point: 519.9ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 205.2ºC

Direct Red 81

Direct Red 81 is a diazo dye with a very high water solubility. The dye adsorption efficiency of Direct Red 81 is increased by increasing the adsorbent dose and adsorption time[1].

  • CAS Number: 2610-11-9
  • MF: C29H19N5Na2O8S2
  • MW: 675.59900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 240ºC
  • Flash Point: N/A

N,N,N-Trimethyldecan-1-aminium-d21 bromide

N,N,N-Trimethyldecan-1-aminium-d21 bromide is the deuterium labeled N,N,N-Trimethyldecan-1-aminium bromide[1].

  • CAS Number: 1515861-67-2
  • MF: C13H9D21BrN
  • MW: 301.42
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methoxychlor-d6

Methoxychlor-d6 is the deuterium labeled Methoxychlor[1].

  • CAS Number: 106031-79-2
  • MF: C16H9D6Cl3O2
  • MW: 351.685
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 436.2±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 149.4±28.8 °C

DEPTOR-IN-1

DEPTOR-IN-1 is a novel putative DEPTOR inhibitor with a Kd value of 9.3 μM.

  • CAS Number: 2615911-12-9
  • MF: C24H16Cl2FNO4
  • MW: 472.29
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sinigrin monohydrate

Sinigrin (hydrate) is a natural aliphatic glucosinolate present in plants of the Brassicaceae family. Sinigrin (hydrate) exhibits anti-cancer, antibacterial, antifungal, antioxidant and anti-inflammatory activities[1].

  • CAS Number: 64550-88-5
  • MF: C10H18KNO10S2
  • MW: 415.479
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 127-130ºC
  • Flash Point: N/A

Emicizumab

Emicizumab is a bispecific monoclonal antibody that bridges activated factor IX and factor X to replace the function of missing activated factor VIII, thereby restoring hemostasis. Emicizumab can be used for hemophilia A research[1].

  • CAS Number: 1610943-06-0
  • MF:
  • MW:
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Octyl 4-methoxycinnamate

Octinoxate is an organic compound that is an ingredient in some sunscreens and lip balms, primarily used is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage. It is also used to reduce the appearance of scars.

  • CAS Number: 5466-77-3
  • MF: C18H26O3
  • MW: 290.397
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 405.3±20.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 171.6±16.4 °C

Chlorovaltrate K

Chlorovaltrate K is a chlorinated valepotriate with anticancer effects. Chlorovaltrate K shows moderate cytotoxicity against A549, PC-3M, HCT-8 and Bel 7402 cell lines with IC50 values of 2.32-8.26 μM[1].

  • CAS Number: 96801-92-2
  • MF: C22H33ClO8
  • MW: 460.95
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 530.1±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 274.4±30.1 °C

Y12196

Y12196 is a novel succinate dehydrogenase inhibitor (SDHI) which exhibits strong fungicidal activity against F. graminearum.

  • CAS Number: 1671025-91-4
  • MF: C18H13Cl2F2N3O2
  • MW: 412.22
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

19:0-12:0-19:0 TG-d5

19:0-12:0-19:0 TG-d5 is deuterium labeled 19:0-12:0-19:0 TG.

  • CAS Number: 944709-21-1
  • MF: C53H97D5O6
  • MW: 840.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A