Bimosiamose
Modify Date: 2025-08-21 22:00:00
Bimosiamose structure
|
Common Name | Bimosiamose | ||
|---|---|---|---|---|
| CAS Number | 187269-40-5 | Molecular Weight | 862.911 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 1051.0±65.0 °C at 760 mmHg | |
| Molecular Formula | C46H54O16 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 309.7±27.8 °C | |
Use of BimosiamoseBimosiamose is a pan-selectin antagonist, inhibits E-, P-, and L-selectin with IC50s of 88 μM, 20 μM, and 86 μM, respectively, and can be used in the research of inflammatory disease. |
| Name | bimosiamose |
|---|---|
| Synonym | More Synonyms |
| Description | Bimosiamose is a pan-selectin antagonist, inhibits E-, P-, and L-selectin with IC50s of 88 μM, 20 μM, and 86 μM, respectively, and can be used in the research of inflammatory disease. |
|---|---|
| Related Catalog | |
| Target |
IC50: 88 μM (E-selectin), 20 μM (P-selectin), 86 μM (L-selectin)[1] |
| In Vitro | Bimosiamose is a pan-selectin antagonist, inhibits E-, P-, and L-selectin with IC50s of 88 μM, 20 μM, and 86 μM, respectively, and can be used in the research of inflammatory disease[1]. |
| In Vivo | Bimosiamose (25 mg/kg, i.v.) significantly improves the survival in rats subjected to severe hepatic ischemia and reperfusion. Bimosiamose also causes lower ALT enzyme levels and decreases neutrophil infiltration[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 1051.0±65.0 °C at 760 mmHg |
| Molecular Formula | C46H54O16 |
| Molecular Weight | 862.911 |
| Flash Point | 309.7±27.8 °C |
| Exact Mass | 862.341187 |
| LogP | 3.04 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.649 |
| InChIKey | RYWCQJDEHXJHRI-XJMXIVSISA-N |
| SMILES | O=C(O)Cc1cccc(-c2cc(CCCCCCc3ccc(OC4OC(CO)C(O)C(O)C4O)c(-c4cccc(CC(=O)O)c4)c3)ccc2OC2OC(CO)C(O)C(O)C2O)c1 |
| Hazard Codes | Xn |
|---|
| bimosiamose |
| [1,1'-Biphenyl]-3-acetic acid, 3',3''-(1,6-hexanediyl)bis[6'-(α-D-mannopyranosyloxy)- |
| 97B5KCW80W |
| 2,2'-{1,6-Hexanediylbis[6'-(α-D-mannopyranosyloxy)-3',3-biphenyldiyl]}diacetic acid |
| 8074 |