1610943-06-0
1610943-06-0 structure
- Name: Emicizumab
- Chemical Name: Emicizumab
- CAS Number: 1610943-06-0
- Molecular Formula:
- Molecular Weight:
- Catalog: Research Areas Cardiovascular Disease
- Create Date: 2023-04-15 17:21:40
- Modify Date: 2024-03-29 21:11:32
-
Emicizumab is a bispecific monoclonal antibody that bridges activated factor IX and factor X to replace the function of missing activated factor VIII, thereby restoring hemostasis. Emicizumab can be used for hemophilia A research[1].
| Name | Emicizumab |
|---|
| Description | Emicizumab is a bispecific monoclonal antibody that bridges activated factor IX and factor X to replace the function of missing activated factor VIII, thereby restoring hemostasis. Emicizumab can be used for hemophilia A research[1]. |
|---|---|
| Related Catalog | |
| In Vivo | Emicizumab (1.5-10 mg/kg，静脉注射，尾夹出血前 24 小时)部分纠正血友病a型出血模型中的失血，FVIII 等效为 9 U/dL[1]。 Emicizumab (3 mg /kg, 静脉注射) 联合低剂量 FVIII (10 U/dL) 时可提供额外的止血活性[1]。 Animal Model: FVIII-deficient mice[1] Dosage: 1.5-10 mg/kg Administration: IV, 24 hours before tail-clip bleeding was performed Result: Significantly reduced blood loss in a tail-clip-bleeding model using FVIII-deficient mice. |
| References |
| No Any Chemical & Physical Properties |