Cyclic PSAP peptide is a cyclic pentapeptide (DWLPK). Cyclic PSAP peptide exhibits drug-like properties and could inhibit metastatic spread and restrain tumor development in general in vivo[1].
2-Amino-3-mercaptopropanoic acid hydrochloride hydrate is a cysteine derivative[1].
Riletamotide is an immunological agent for active immunization[1].
DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS is a biological active peptide. (DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS is also called HIV protease substrate I in some literature. It is widely used for the continuous assay for HIV protease activity. The 11-kD protease (PR) encoded by the human immunodeficiency virus 1 (HIV-1) is essential for the correct processing of viral polyproteins and the maturation of infectious virus, and is therefore a target for the design of selective acquired immunodeficiency syndrome (AIDS) therapeutics. The FRET-based fluorogenic substrate is derived from a natural processing site for HIV-1 PR. Incubation of recombinant HIV-1 PR with the fluorogenic substrate resulted in specific cleavage at the Tyr-Pro bond and a time-dependent increase in fluorescence intensity that is linearly related to the extent of substrate hydrolysis. The fluorescence quantum yields of the HIV-1 PR substrate in the FRET assay increased by 40.0- and 34.4-fold, respectively, per mole of substrate cleaved. Because of its simplicity and precision in the determination of reaction rates required for kinetic analysis, this substrate offers many advantages over the commonly used HPLC or electrophoresis-based assays for peptide substrate hydrolysis by retroviral PRs. Abs/Em = 340nm/490nm.)
Fissitungfine B is a compound extracted from the tropical medicinal plant Fissistigma tungfangense. Fissitungfine B has strong anticancer activity[1].
Collagenase is a proteolytic enzyme, which breaks the peptide bonds in collagen. Collagenase has good research potential in disc herniation, keloid, cellulite, lipoma, as well as peyronie's disease and dupuytren fracture[1].
Cibisatamab (CEA-TCB), a T cell bispecific antibody, binds Carcino-Embryonic Antigen (CEA) on cancer cells and CD3 on T cells. Cibisatamab (CEA-TCB) triggers T cell killing of cancer cell lines expressing moderate to high levels of CEA at the cell surface. Cibisatamab (CEA-TCB) can be used for colorectal cancer research[1].
Fmoc-Gly-Ser(psi(Me,Me)pro)-OH is a dipeptide.
BFCAs-1 is a polyamino polycarboxylic bifunctional chelating agent(BFCAs); a broad range of applications in chemistry, biology and medicine and diagnostic imaging (MRI, SPECT, PET).
Oleoside 11-methyl ester is a secoiridoid glucoside and possesses a strong cytotoxic activity against Hep-G2 cells[1].
AI-3 is a potent ARE (antioxidant response element) activator. AI-3 increases the NQO1 at the transcript levels and protein expression levels. AI-3 has the potential for the research of oxidative stress related diseases[1].
H-Pro-Pro-Asp-NH2 is a potent and selective catalyst for asymmetric aldol reactions. H-Pro-Pro-Asp-NH2 catalyzes aldol reactions between acetone and several aldehydes[1][2].
Liquidambaric lactone is a compound isolated from Euonymus grandiflorus Wall[1].
Ezetimibe hydroxy glucuronide (SCH 488128) is a trace metabolite detected in dog and human plasma samples after oral administration of Ezetimibe (HY-17376)[1].
Corchoionol C is a n-butanol-soluble fraction of the whole plant extract of Pulicaria undulate[1].
4,7-Dichloroquinoline-15N is the 15N labeled 4,7-Dichloroquinoline[1].
D-pinitol (3-O-Methyl-D-chiro-inositol) is a natural compound presented in several plants, like Pinaceae and Leguminosae plants. D-pinitol exerts hypoglycemic activity and protective effects in the cardiovascular system[1][2].
4-(tert-Butyl)aniline-d15 is the deuterium labeled 4-(tert-Butyl)aniline[1].
Hernandesine is isolated from T. flavum L[1].
Lys-Conopressin-G, a vasotocin-like peptide, can be isolated from the venom of the worm-hunting snail (conus imperialis)[1][2].
Ceefourin 2 is a potent and highly selective inhibitor of MRP4. Ceefourin 2 inhibits the transport of MRP4 substrates but is not selective for other ABC transporters. Ceefourin 2 shows lower cytotoxicity and higher microsomal and acid stability[1].
N-trans-p-coumaroyloctopamine is a phenylpropanoid amide isolated from eggplant (Solanum melongena L.)[1].
14-Benzoylmesaconine-8-palmitate (compound 4) is a lipo-alkaloid compound that can be found in A. toxicum[1].
2',3'-Dideoxy-5-iodouridine is used for gene sequencing and as a research tool for antiviral and anticancer studies[1].
(3S,4S)-Tivantinib is a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET. (3S,4S)-Tivantinib has two novel targets, GSK3α and GSK3β, which play an important role in the cellular mechanism of non-small cell lung cancer (NSCLC)[1].
Gemcabene (PD-72953), a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) and lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP), exerting anti-inflammatory activity[1][2][3].
H-Ala-Val-OH is adipeptide.
Erigoster B is the active component of Erigeron breviscapus (Vant.) Hand.-Mazz. (an important Chinese herb), which has neuroprotective effects. Erigoster B can be used to prepare anti-nerve damage reagents to inhibit various nerve cell damage. It can also be used for cardio-cerebrovascular and tumor research[1][2][3].
Commendamide is a GPCR G2A/GPR132 agonist (EC50: 11.8 μM). Commendamide can be used for research of autoimmunity and atherosclerosis[1].
Intermedin (rat) is a biologically active peptide.