Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Periplanetin

Periplanetin, a 1-benzoyl-β-d-glucose, can be isolated from the secretion of the laterocervical organ of Periplaneta americana L. and Blatta orientalis L[1].

  • CAS Number: 21056-52-0
  • MF: C13H16O7
  • MW: 284.26
  • Catalog: Others
  • Density: 1.5g/cm3
  • Boiling Point: 507.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 194.1ºC

3β-Hydroxy-5-cholestenoic acid-d5

3β-Hydroxy-5-cholestenoic acid-d5 is deuterium labeled 3β-Hydroxy-5-cholestenoic acid.

  • CAS Number: 1620239-03-3
  • MF: C27H39D5O3
  • MW: 421.67
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ethoxylated hydrogenated castor oil

Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo[1].

  • CAS Number: 61788-85-0
  • MF: C21H23ClFNO2
  • MW: 375.864
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 529.0±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 273.8±30.1 °C

MDL 72527

MDL 72527 dihydrochloride is a potent polyamine oxidase (PAO) inhibitor. MDL 72527 dihydrochloride shows a lysosomotropic effect. MDL 72527 dihydrochloride shows neuroprotective effects[1][2].

  • CAS Number: 93565-01-6
  • MF: C12H22Cl2N2
  • MW: 265.22200
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: 300.7ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 159.2ºC

D-β-homoserine

(S)-3-Amino-4-hydroxybutanoic acid is a serine derivative[1].

  • CAS Number: 16504-57-7
  • MF: C4H9NO3
  • MW: 119.119
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 374.5±32.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 180.3±25.1 °C

Smilagenin acetate

Smilagenin acetate is a Sapogenin derivative extracted from patent US20030004147A1. Smilagenin acetate increases the expression of acetylcholine m2 receptors and can be used for the research of dementia[1].

  • CAS Number: 4947-75-5
  • MF: C29H46O4
  • MW: 458.67300
  • Catalog: Neurological Disease
  • Density: 1.11g/cm3
  • Boiling Point: 527.5ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 221.8ºC

Telazorlimab

Telazorlimab (GBR-830) is a humanized monoclonal antibody against OX40 costimulatory receptor on activated T cells. Telazorlimab can be used for the research of autoimmune diseases[1].

  • CAS Number: 2126777-87-3
  • MF:
  • MW:
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Secoxyloganin methyl ester

Dimethyl secologanoside (compound 2) is an e iridoid isolated from the leaves of Khaya senegalensis[1].

  • CAS Number: 74713-15-8
  • MF: C18H26O11
  • MW: 418.39
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 586.2±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 204.1±23.6 °C

N-BENZYLGLYCINE TERT-BUTYL ESTER

tert-Butyl benzylglycinate is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 7662-76-2
  • MF: C13H19NO2
  • MW: 221.29500
  • Catalog: Others
  • Density: 1.019±0.06 g/cm3(Predicted)
  • Boiling Point: 151-152 °C(Press: 12 Torr)
  • Melting Point: N/A
  • Flash Point: N/A

Tween 80

Tween 80 is a surfactant which can also reduce bacterial attachment and inhibit biofilm formation.

  • CAS Number: 9005-65-6
  • MF: C46H52N5O8P
  • MW: 833.907
  • Catalog: Biochemical Assay Reagents
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 695.8±55.0 °C at 760 mmHg
  • Melting Point: -21ºC
  • Flash Point: 207.1±25.0 °C

Potassium hydrogen phosphate hydrate (2:1:3)

Dipotassium hydrogen phosphate trihydrate affects pH level in liquid. Dipotassium hydrogen phosphate (trihydrate) can be used as an excipient, such as pH regulator, buffer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

  • CAS Number: 16788-57-1
  • MF: H7K2O7P
  • MW: 228.22
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Melittoside

Melittoside is a natural compound.

  • CAS Number: 19467-03-9
  • MF: C21H32O15
  • MW: 524.470
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 890.0±65.0 °C at 760 mmHg
  • Melting Point: 167-168 ºC
  • Flash Point: 492.1±34.3 °C

Cyclo(Ile-Ala)

Cyclo(Ile-Ala) is found in marine actinomycete 11014 I.[1].

  • CAS Number: 90821-99-1
  • MF: C9H16N2O2
  • MW: 184.24
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 432.0±38.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 194.2±26.9 °C

Fmoc-O-tert-butyl-D-threonine

(2S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(tert-butoxy)butanoic acid is a threonine derivative[1].

  • CAS Number: 138797-71-4
  • MF: C23H27NO5
  • MW: 397.464
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 581.7±50.0 °C at 760 mmHg
  • Melting Point: -130ºC
  • Flash Point: 305.6±30.1 °C

HKPerox-2

HKPerox-2 is an excellently selective and sensitive green fluorescent probe toward H2O2 over 30-fold other tested ROS/RNS in chemical and biological systems. HKPerox-2 is a O-methyl rhodol derivative and specifically recognize H2O2 based on a tandem payne/dakin reaction[1].

  • CAS Number: 2245230-79-7
  • MF: C32H23NO10
  • MW: 581.53
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

asparagusic acid

Asparagusic acid (1,2-dithiolane-4-carboxylic acid) is unique to asparagus. The compound is responsible for the odorous urine excreted after eating asparagus. Its derivatives ihydroasparagusic acid have anti-inflammatory effect.

  • CAS Number: 2224-02-4
  • MF: C4H6O2S2
  • MW: 150.21900
  • Catalog: Others
  • Density: 1.503g/cm3
  • Boiling Point: 323.9ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 149.7ºC

OVA (257-264), scrambled

OVA (257-264), scrambled is a biological active peptide. (Out-of-order control peptide of HY-P1489)

  • CAS Number: 1213245-88-5
  • MF: C45H74N10O13
  • MW: 963.13
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ametryn

Ametryn, a member of the Triazine chemical family, is a herbicide which inhibits photosynthesis and other enzymatic processes. Ametryn is effective against annual broadleaf weeds and grasses[1].

  • CAS Number: 834-12-8
  • MF: C9H17N5S
  • MW: 227.330
  • Catalog: Metabolic Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 396.4±25.0 °C at 760 mmHg
  • Melting Point: 84-85°C
  • Flash Point: 193.5±23.2 °C

Human Growth Hormone (1-43)

Human Growth Hormone (1-43) is an N-terminal fragment of human growth hormone with specific and pronounced insulin-like activity. Human Growth Hormone (1-43) can be used to study the function and metabolic pathways of growth hormone, a potential obesity-related factor[1].

  • CAS Number: 96827-07-5
  • MF: C11H13BrN2O5
  • MW: 333.135
  • Catalog: Endocrinology
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Trt-L-Hse-OH * TEA

N-Trityl-L-homoserine triethylamine salt is a serine derivative[1].

  • CAS Number: 102056-97-3
  • MF: C29H38N2O3
  • MW: 462.62400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Benzyllinoleamide

N-Benzyllinoleamide, isolated from Lepidium meyenii Walp., has pharmaceutical property against exercise-induced fatigue[1].

  • CAS Number: 18286-71-0
  • MF: C25H39NO
  • MW: 369.58300
  • Catalog: Neurological Disease
  • Density: 0.933±0.06 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CyClo(-D-Ala-Val)

Cyclo(D-Ala-Val) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 15136-27-3
  • MF: C8H14N2O2
  • MW: 170.21
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Nicotinic acid N-oxide

Nicotinic acid N-oxide is used to treat hyperlipoidemia.

  • CAS Number: 2398-81-4
  • MF: C6H5NO3
  • MW: 139.109
  • Catalog: Cardiovascular Disease
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 469.0±18.0 °C at 760 mmHg
  • Melting Point: 254-255 °C (dec.)(lit.)
  • Flash Point: 237.4±21.2 °C

Native Aspergillus niger Amyloglucosidase

Glucoamylase is an enzyme derived from many sources including plants, animals and microorganisms, can be use for industrial production. Glucoamylase can be widely used for starch saccharification, brewing and distilling industry[1].

  • CAS Number: 9032-08-0
  • MF: C28H31ClN4O
  • MW: 475.025
  • Catalog: Metabolic Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 778.3±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 424.5±32.9 °C

(20R)-Ginsenoside Rh1

(20R)-Ginsenoside Rh1, the R isomer of Ginsenoside Rh1 isolated from Panax Ginseng, inhibits the thrombin-induced conversion of fibrinogen to fibrin[1].

  • CAS Number: 80952-71-2
  • MF: C36H62O9
  • MW: 638.872
  • Catalog: Others
  • Density: 1.23±0.1 g/cm3
  • Boiling Point: 755.1±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 410.5±32.9 °C

2,4,5-trimethoxybenzoic acid

2,4,5-Trimethoxybenzoic acid is a compound identified in purple perilla extracts. 2,4,5-Trimethoxybenzoic acid inhibits M1 macrophage phenotype-mediated inflammation in diabetes[1].

  • CAS Number: 490-64-2
  • MF: C10H12O5
  • MW: 212.199
  • Catalog: Metabolic Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 300.0±0.0 °C at 760 mmHg
  • Melting Point: 143-145 °C(lit.)
  • Flash Point: 134.0±20.0 °C

H-D-Ala-Obzl.Tos.OH

H-D-Ala-OBzl.TosOH is an alanine derivative[1].

  • CAS Number: 41036-32-2
  • MF: C17H21NO5S
  • MW: 351.417
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 256.5ºC at 760 mmHg
  • Melting Point: 115ºC
  • Flash Point: 119.6ºC

jesaconitine

Jesaconitine is a toxic alkaloid. Jesaconitine can be derived from Aconitum. Jesaconitine is one of the major metabolites that can be detected in the blood of the right atrium after aconitum poisoning. Various types of arrhythimia are characteristic in aconitine intoxication[1].

  • CAS Number: 16298-90-1
  • MF: C35H49NO12
  • MW: 675.76
  • Catalog: Cardiovascular Disease
  • Density: 1.37g/cm3
  • Boiling Point: 748.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 406.2ºC

SP-420

SP-420 is a desferrithiocin analogue with iron-clearing efficiency with ICE value of 26.7; more potent than desferrithiocin.

  • CAS Number: 911714-45-9
  • MF: C16H21NO6S
  • MW: 355.406
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 562.2±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 293.8±32.9 °C

trans-Cephalosporin

Trans substituted cephalosporin is an effective NDM-1 inhibitor,with an IC50 value of 0.13 μM.

  • CAS Number: 2757462-75-0
  • MF: C16H14N2O4S3
  • MW: 394.49
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A