CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site[1].
6-O-β-D-Galactopyranosyl-D-galactose, a disaccharide, is a part of the polysaccharide main chain with β-(1→6)-glycoside bonds with a side chain bonded to the main one by the β-(1→3) bond[1].
Dehydro-ZINC39395747 is a derivative of ZINC39395747. ZINC39395747 is a potent cytochrome b5 reductase 3 (CYB5R3) inhibitor with an IC50 of 9.14 μM and a Kd of 1.11 μM. ZINC39395747 can increase NO bioavailability in vascular cells[1].
PAMP-12(human, porcine) is a major component of immunoreactive (ir)-PAMP, is processed from the adrenomedullin precursor, is a potent hypotensive peptide and participates in cardiovascular control[1].
Fesomersen (sodium) is an antisense oligonucleotide designed to inhibit the production of Factor XI.
Erysotramidine is an alkaloid that can be isolated from the stem barks of Erythrina stricta[1].
IDR 1002 is an IPO-38 antibody marker protein. IDR1002 catalyzes the conversion of arginine to citrulline. IDR 1002 can be usedto study the role of citrullinated modification of protein in cancer biology[1].
Nurr1 agonist 4 (compound 8) is a high-affinity Nurr1 agonist with EC50 of 2.1 μM[1].
n-Undecyl β-D-maltopyranoside is a malted glycoside.
Mangafodipir is a contrast agent delivered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver.
1'-Hydroxymidazolam-13C3 is the 13C labeled 1'-Hydroxymidazolam[1].
16:0 (Rac)-PC-d80 is deuterium labeled 16:0 (Rac)-PC.
Benzoylaconine(Isaconitine; Pikraconitin) is an alkaloid in the Chinese traditional medicine Radix Aconiti Lateralis Preparata (Fuzi).
(R,S,R)-ML334 is the inactive isomer of ML334 (HY-110258), and can be used as an experimental control. ML334 is a potent, cell permeable activator of NRF2 by inhibition of Keap1-NRF2 protein-protein interaction. ML334 binds to Keap1 Kelch domain with a Kd of 1 μM. ML334 stimulates NRF2 expression and nuclear translocation and induces antioxidant response elements (ARE) activity[1][2].
BAY-850 is a potent and isoform selective ATPase family AAA domain-containing protein 2 (ATAD2) inhibitor, with an IC50 of 166 nM.
Elarekibep (PRS-060) (AZD1402) is a high affinity, slowly dissociating, long-acting full antagonist of IL-4Ra. Elarekibep can be used for the research of T2 endotype asthma[1].
LKKTETQ, a peptide segment, is the active site within the protein thymosin β4 responsible for actin binding, cell migration and wound healing[1].
Diethylamine-d10 hydrobromide is the deuterium labeled Diethylamine hydrobromide[1].
1-Acetyl-3-o-toluyl-5-fluorouracil is a potent an antineoplastic agent.
2-Fluorobenzoic acid-d4 is the deuterium labeled 2-Fluorobenzoic acid[1].
Spirostan-3-ol is a useful tool to keep bees away from areas recently treated with toxic insecticides[1].
Orcinol (3,5-Dihydroxytoluene) is an organic compound used as biological dye and indicator for proteomics research.
Letaplimab (IBI-188) is a humanized IgG4 anti-CD47 monoclonal antibody. CD47 is overexpressed on cancer cells, it is a ligand for SIRPα. Letaplimab enhances tumor cell phagocytosis[1].
Amylin, amide, rat is a potent and high affinity ligand of Amylin receptor AMY1 and AMY3 receptors and variably of AMY2 receptors; binding studies are generally used for the latter receptor.
Benzyl 4-hydroxybenzoate is a prominent material. Benzyl 4-hydroxybenzoate can be used as an excipient, such as bacteriostatic agent, preservative. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
6-(Methylthio)purine-d3-1 is the deuterium labeled 6-(Methylthio)purine[1].
Adrenocorticotropic Hormone (ACTH) (1-39), human is a melanocortin receptor agonist.
4-Fluoro-DL-glutamic acid is a glutamic acid derivative[1].
6''-Acetylhyperin is a natural phenolic compounds that could be found in Nymphaea odorata[1].
Methyl L-pyroglutamate ((S)-Methyl 5-oxopyrrolidine-2-carboxylate;L-Pyroglutamic acid methyl ester) is isolated from P. oleracea and has anti-inflammatory activity[1].