433248-87-4

433248-87-4 structure

Name: Dehydro-ZINC39395747
Chemical Name: Dehydro-ZINC39395747
CAS Number: 433248-87-4
Molecular Formula: C₁₂H₉N₃O₂S₂
Molecular Weight: 291.35
Catalog: Research Areas Others
Create Date: 2020-05-01 17:59:10
Modify Date: 2024-01-03 14:02:26
Dehydro-ZINC39395747 is a derivative of ZINC39395747. ZINC39395747 is a potent cytochrome b5 reductase 3 (CYB5R3) inhibitor with an IC50 of 9.14 μM and a Kd of 1.11 μM. ZINC39395747 can increase NO bioavailability in vascular cells[1].

Name	Dehydro-ZINC39395747

Description	Dehydro-ZINC39395747 is a derivative of ZINC39395747. ZINC39395747 is a potent cytochrome b5 reductase 3 (CYB5R3) inhibitor with an IC50 of 9.14 μM and a Kd of 1.11 μM. ZINC39395747 can increase NO bioavailability in vascular cells[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Rahaman MM, et al. Structure Guided Chemical Modifications of Propylthiouracil Reveal Novel Small Molecule Inhibitors of Cytochrome b5 Reductase 3 That Increase Nitric Oxide Bioavailability. J Biol Chem. 2015 Jul 3;290(27):16861-72.