Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Ethyl 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoate

Ethyl 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoate is a tyrosine derivative[1].

  • CAS Number: 16323-00-5
  • MF: C12H17NO3
  • MW: 223.268
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 350.2±27.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 165.6±23.7 °C

p-Hydroxyphenethyl anisate

p-Hydroxyphenethyl anisate is a main constituent of Notopterygium Radix[1].

  • CAS Number: 87932-34-1
  • MF: C16H16O4
  • MW: 272.296
  • Catalog: Others
  • Density: 1.199±0.06 g/cm3
  • Boiling Point: 446.5±30.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 165.4±18.1 °C

Chromotrope 2R

Chromotrope 2R can be used as a chromogenic analytical probe for the quantification of proteins. Basic proteins stained red and the peak wavelength red shifts from 501.6 nm to 567 nm[1].

  • CAS Number: 4197-07-3
  • MF: C16H10N2Na2O8S2
  • MW: 468.369
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

6,7-Diaminoquinoxaline-2,3-dione, Dihydrochloride

6,7-Diaminoquinoxaline-2,3-dione dihydrochloride is a fluorescent dye that reacts with aldehydes[1].

  • CAS Number: 17498-26-9
  • MF: C8H10Cl2N4O2
  • MW: 265.09700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: >300ºC
  • Flash Point: N/A

Orziloben

Orziloben is a medium chain fatty acid (MCFA) analogue[1].

  • CAS Number: 1555822-28-0
  • MF: C13H18O3
  • MW: 222.28
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Thymoctonan

Thymoctonan (THF-γ2) is the immunomodulatory octapeptide, thymic humoral factor γ2. Thymoctonan has the half-life less than 6 min at 37 °C in blood from human, rat and mouse[1].

  • CAS Number: 107489-37-2
  • MF: C43H67N9O13
  • MW: 918.04500
  • Catalog: Inflammation/Immunology
  • Density: 1.285g/cm3
  • Boiling Point: 1331.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 758.8ºC

Bromoethanol-d4

Bromoethanol-d4 is the deuterium labeled Bromoethanol[1].

  • CAS Number: 81764-55-8
  • MF: C2HBrD4O
  • MW: 128.98900
  • Catalog: Others
  • Density: 1.819 g/mL at 25ºC(lit.)
  • Boiling Point: 56-57ºC20 mm Hg(lit.)
  • Melting Point: N/A
  • Flash Point: >230 °F

ANAT inhibitor-2

ANAT inhibitor-2 is a ANAT inhibitor for canavan disease, with an IC50 value of 20 μM.

  • CAS Number: 1048244-34-3
  • MF: C22H23F2NO3
  • MW: 387.42
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-(Gly)3-Lys(N3)-OH

The azide function is widely used for coupling to alkyne-containing fragments via the renowned Click reaction. Polyglycine fragments containing up to 7 glycines are reported to bind to surfaces and have potential application in nanotechnology constructs: constructs of Gly7-NHCH2-fragment containing peptides bind on mica surface in aqueous solution[1][2].

  • CAS Number: 2250437-45-5
  • MF: C12H21N7O5
  • MW: 343.34
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isovanillin

Isovanillin is an aldehyde oxidase inhibitor[1]. Antispasmodic activities[2]. Antidiarrheal activities[3].

  • CAS Number: 621-59-0
  • MF: C8H8O3
  • MW: 152.147
  • Catalog: Metabolic Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 308.1±0.0 °C at 760 mmHg
  • Melting Point: 113-116 °C
  • Flash Point: 119.9±15.3 °C

Viaminate

Viaminate is a derivative of Retinoic acid, which is used for the treatment of severe acne and other keratinization disorders.

  • CAS Number: 53839-71-7
  • MF: C29H37NO3
  • MW: 447.61
  • Catalog: Inflammation/Immunology
  • Density: 1.071 g/cm3
  • Boiling Point: 619.4ºCat 760 mmHg
  • Melting Point: 177-182 °C
  • Flash Point: 328.4ºC

PX-12

PX-12(IV-2) is an irreversible inhibitor of Thioredoxin-1 (Trx-1); inhibits the growth of MCF-7 and HT-29 cells with IC50 values of 1.9 and 2.9 μM, respectively.

  • CAS Number: 141400-58-0
  • MF: C7H12N2S2
  • MW: 188.314
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 330.0±25.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 153.4±23.2 °C

Angeloylgomisin Q

Angeloylgomisin Q is a new dibenzocyclooctadiene lignan from the stems of Schisandra sphaerandra[1]. Angeloylgomisin Q has the potential for alzheimer's disease research[2].

  • CAS Number: 72561-28-5
  • MF: C29H38O9
  • MW: 530.607
  • Catalog: Neurological Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 638.0±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 201.6±25.0 °C

Macarangioside D

Macarangioside D, a megastigmane glucoside, possesses radical-scavenging activity[1].

  • CAS Number: 819870-23-0
  • MF: C19H30O8
  • MW: 386.43
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Acetyl-(Tyr1,D-Phe2)-GRF (1-29) amide

[Ac-Tyr1,D-Phe2]GRF 1-29, amide (human), a growth hormone releasing factor (GRF) analogue, is a vasoactive intestinal peptide (VIP) antagonist[1].

  • CAS Number: 93965-89-0
  • MF: C157H252N44O43S
  • MW: 3476.015
  • Catalog: Cardiovascular Disease
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Terpinine-4-ol

Terpinen-4-ol (4-Carvomenthenol), a naturally occurring monoterpene, is the main bioactive component of tea-tree oil. Terpinen-4-ol suppresses inflammatory mediator production by activated human monocytes. Terpinen-4-ol significantly enhances the effect of several chemotherapeutic and biological agents[1][2][3].

  • CAS Number: 562-74-3
  • MF: C10H18O
  • MW: 154.249
  • Catalog: Inflammation/Immunology
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 209.0±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 79.4±0.0 °C

DOTAGA-tetra (t-Bu ester)

DOTA-GA(tBu)4 is a macrocyclic chelator used in medical imaging[1].

  • CAS Number: 306776-79-4
  • MF: C35H64N4O10
  • MW: 700.90
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TMN 355

TMN355 is a potent chemical cyclophilin A inhibitor and reduces foam cell formation and cytokine secretion. TMN355 is used for atherosclerosis[1].

  • CAS Number: 1186372-20-2
  • MF: C21H14ClFN2O2
  • MW: 380.79900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Oleic alcohol

Oleyl alcohol is an active compound. Oleyl alcohol can be used for various studies[1].

  • CAS Number: 143-28-2
  • MF: C18H36O
  • MW: 268.478
  • Catalog: Others
  • Density: 0.8±0.1 g/cm3
  • Boiling Point: 333.0±0.0 °C at 760 mmHg
  • Melting Point: 0-5.0 °C(lit.)
  • Flash Point: 120.7±15.6 °C

Polycarbophil

Polycarbophil can be used as an excipient, such as ointment base, release blocker, thickener, emulsifier. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

  • CAS Number: 9003-97-8
  • MF: C11H9N3O2.Na+
  • MW: 238.19786
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(4E)-1,7-Bis(4-hydroxyphenyl)-4-hepten-3-one

Platyphyllenone is a narutal product that can be isolated from Alnus japonica[1].

  • CAS Number: 56973-65-0
  • MF: C19H20O3
  • MW: 296.36
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 529.1±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 287.9±26.6 °C

2'-O-Methylphloretin (4,2',4'-Trihydroxy-6'-methoxydihydrochalcone)

2′-O-Methylphloretin (compound 3) is a flavonoid derivative. 2′-O-Methylphloretin can be isolated from the leaves of Melodorum siamensis. 2′-O-Methylphloretin inhibits the tumor cell line replication[1].

  • CAS Number: 111316-17-7
  • MF: C16H16O5
  • MW: 288.30
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Santin

Santin is a flavonol isolated from Dodonaea uscosa[1].

  • CAS Number: 27782-63-4
  • MF: C18H16O7
  • MW: 344.32
  • Catalog: Others
  • Density: 1.45g/cm3
  • Boiling Point: 597ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 219.9ºC

1-Benzoylpiperazine-d8

1-Benzoylpiperazine-d8 is the deuterium labeled 1-Benzoylpiperazine[1].

  • CAS Number: 1219805-49-8
  • MF: C11H6D8N2O
  • MW: 198.291
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 341.3±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 160.2±25.9 °C

Lophanthoidin E

Lophanthoidin E is a diterpenoids compound isolated from the dried leaves of Rabdosia lophanthoides[1].

  • CAS Number: 120462-45-5
  • MF: C22H30O7
  • MW: 406.469
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 551.3±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 186.4±23.6 °C

Cd(II) protoporphyrin IX

Cd(II) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway[1].

  • CAS Number: 80216-25-7
  • MF: C34H32CdN4O4
  • MW: 673.05300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-Dap(Z)-OH

(S)-3-Benzyloxycarbonylamino-2-(Boc-amino)propionic acid is an alanine derivative[1].

  • CAS Number: 65710-57-8
  • MF: C16H22N2O6
  • MW: 338.356
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 546.2±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 284.1±30.1 °C

Sauristolactam (Saurolactam)

Sauristolactam, a natural aristolactam isolated from aerial portions of Saururus chinensis, has significant neuroprotective activity against glutamate-induced toxicity in primary cultured rat cortical cells[1]. Sauristolactam also inhibits the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis and has the potential to inhibit osteoclast differentiation[2].

  • CAS Number: 128533-02-8
  • MF: C17H13NO3
  • MW: 279.29
  • Catalog: Neurological Disease
  • Density: 1.403g/cm3
  • Boiling Point: 579ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 304ºC

1-Propanamine, 3-azido-

3-Azidopropylamine is a click chemistry reagent containing an azide group. 3-Azidopropylamine can react with the starch sugar of potato starch for complexation and transfection of plasmid DNA[1].

  • CAS Number: 88192-19-2
  • MF: C3H8N4
  • MW: 100.12200
  • Catalog: Others
  • Density: 1.020 g/cm3
  • Boiling Point: 50 °C/15 mmHg
  • Melting Point: N/A
  • Flash Point: 60 °C

phenethyl alcohol xylopyranosyl-(1-6)-glucopyranoside

2-Phenethyl β-primeveroside is a phenplic that can be isolated from Callianthemum taipaicum[1].

  • CAS Number: 129932-48-5
  • MF: C19H28O10
  • MW: 416.42000
  • Catalog: Others
  • Density: 1.49g/cm3
  • Boiling Point: 661.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 353.7ºC