Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

FGF basic (93-110) (human, bovine)

FGF basic (93-110) (human, bovine) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 1807793-49-2
  • MF: C107H155N31O31
  • MW: 2371.56
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Acetyl-PHF6YA amide trifluoroacetate salt

Acetyl-PHF6YA amide is a biologically active peptide.

  • CAS Number: 885610-34-4
  • MF: C32H59N9O8
  • MW: 697.866
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 1143.9±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 645.6±34.3 °C

Kisspeptin-54 (27-54) (human) trifluoroacetate salt

Kisspeptin-54 (27-54) (human) is a polypeptide that can be used for compound synthesis and pharmaceutical research[1][2].

  • CAS Number: 1135442-77-1
  • MF: C149H226N42O39
  • MW: 3229.65
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

KL 001

KL001 is a cryptochrome protein (CRY) stabilizer which specifically interacts with CRY1 and CRY2. KL001 prevents ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. KL001 has the potential to control fasting hormone-induced gluconeogenesis[1][2].

  • CAS Number: 309928-48-1
  • MF: C21H22N2O4S
  • MW: 398.475
  • Catalog: Metabolic Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 578.1±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 303.4±32.9 °C

N3,N3,N6,N6-Tetramethylacridine-3,6-diamine

Acridine Orange base is a cell-permeable fluorescent dye that stains organisms (bacteria, parasites, viruses, etc.) bright orange and, when used under appropriate conditions (pH=3.5, Ex=460 nm), distinguishes human cells in green for detection by fluorescence microscopy. Acridine Orange base fluoresces green when bound to dsDNA (Ex=488, Em=520-524) and red when bound to ssDNA (Ex=457, Em=630-644) or ssRNA (Ex=457, Em=630-644), also can be used in cell cycle assays[1][2][3].

  • CAS Number: 494-38-2
  • MF: C17H19N3
  • MW: 265.353
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 468.6±25.0 °C at 760 mmHg
  • Melting Point: 165ºC (dec.)(lit.)
  • Flash Point: 237.2±23.2 °C

PKCd (8-17)

PKCd (8-17) is a biological active peptide. (This peptide is derived from the V1 domain of protein kinase C (PKC)d. It inhibits phorbol 12-myristate 13-acetate (PMA)-induced PKCd translocation and activation. Inhibition of PKCd reduces ischemia damage in cardiac and cerebral cells, induces proliferation of fibroblasts, and inhibits graft coronary artery disease in mice.)

  • CAS Number: 379711-25-8
  • MF: C50H73N11O18
  • MW: 1116.18
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ES9-17

ES9-17 is a novel CME inhibitor.

  • CAS Number: 55854-43-8
  • MF: C10H8BrNO2S2
  • MW: 318.210
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 435.4±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 217.1±31.5 °C

myo-Inositol Trispyrophosphate Hexasodium Salt

myo-Inositol trispyrophosphate (ITPP) hexasodium, a modifier of haemoglobin, is an allosteric effector that reduces the oxygen‐binding affinity of haemoglobin and facilitates the release of oxygen by red blood cells. myo-Inositol trispyrophosphate can reverse hypoxia, control tumor growth and improve chemotherapy response[1][2][3].

  • CAS Number: 23103-35-7
  • MF: C6H6Na6O21P6
  • MW: 737.88000
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Liriodenine

Liriodenine (Spermatheridine; VLT045) is an aporphine alkaloid isolated from the plant Mitrephora sirikitiae and has anti-cancer activities[1]. Liriodenine induces cell apoptosis, activates the intrinsic pathway by induction of caspase-3 and caspase-9[2].

  • CAS Number: 475-75-2
  • MF: C17H9NO3
  • MW: 275.258
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 531.0±19.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 275.0±21.5 °C

Pigment Red 22

Pigment Red 22, a coloring agent, is used in the formulation of cleansing products, makeup, moisturizers, and night skin care products.

  • CAS Number: 6448-95-9
  • MF: C24H18N4O4
  • MW: 426.42400
  • Catalog: Others
  • Density: 1.34g/cm3
  • Boiling Point: 622.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 330.3ºC

Scabertopin

Scabertopin, isolated from the whole plant of Elephantopus scaber[1], is a sesquiterpene lactone. Scabertopin has been found to be prominent anticancer constituents[2].

  • CAS Number: 185213-52-9
  • MF: C20H22O6
  • MW: 358.39
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 592.7±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 260.5±30.2 °C

DS-1040 tosylate

DS-1040 Tosylate is an inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa), used for the treatment of acute ischemic stroke (AIS).

  • CAS Number: 1335138-89-0
  • MF: C23H35N3O5S
  • MW: 465.61
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

pentafluoroethane-d1

Pentafluoroethane-d1 is the deuterium labeled Pentafluoroethane[1].

  • CAS Number: 87458-21-7
  • MF: C2DF5
  • MW: 121.02800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sphingosine (d12:1)

C12-Sphingosine is a short-chain Sphingosine homologue. C12-Sphingosine inhibits serine palmitoyltransferase activity in primary cultured cerebellar cells[1].

  • CAS Number: 128427-86-1
  • MF: C12H25NO2
  • MW: 215.33200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sterebin F

Sterebin F is a steroid isolated from the Stevia rebaudiana leaves. Sterebin F has hypoglycemic activity[1].

  • CAS Number: 114489-87-1
  • MF: C20H34O4
  • MW: 338.48
  • Catalog: Others
  • Density: 1.138±0.06 g/cm3(Predicted)
  • Boiling Point: 436.6±45.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

Apigenin 7-O-diglucuronide

Apigenin-7-diglucuronide is a flavonoid glycoside and is present in an assortment of medicinal plants with anti-inflammatory or ant-oxidant activities. Apigenin-7-diglucuronide protects retinas against bright light-induced photoreceptor degeneration through the inhibition of retinal oxidative stress and inflammation[1].

  • CAS Number: 74696-01-8
  • MF: C27H26O17
  • MW: 622.49
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sorokinianin

(+)-Sorokinianin is a phytotoxin from an isolate of Bipolaris sorokiniana[1].

  • CAS Number: 162616-73-1
  • MF: C18H28O4
  • MW: 308.413
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

[Tyr8]-Atrial Natriuretic Peptide (5-27), rat

[Tyr8]-Atrial Natriuretic Peptide (5-27), rat is an atrial natriuretic peptide (ANP) analog that relaxes smooth muscle without affecting cGMP levels[1][2].

  • CAS Number: 108703-67-9
  • MF: C98H158N34O33S2
  • MW: 2404.64
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Nocarimidazole A

Nocarimidazole A is a white amorphous solid alkaloid with ultraviolet activity found from marine actinomycete Nocardiopsis[1][2].

  • CAS Number: 1818218-33-5
  • MF: C13H23N3O
  • MW: 237.34
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(-)-lariciresinol

(-)-Lariciresinol is a lignans that can be isolated from Sambucus williamsii. (-)-Lariciresinol stimulates UMR106 cell proliferation[1].

  • CAS Number: 83327-19-9
  • MF: C20H24O6
  • MW: 360.40
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

α-Amylase-IN-3

α-Amylase-IN-3 (Compound 4) is a none-competitive type of α-Amylase inhibitor with an IC50 value of 18.04 μM, which also has radical scavenging activities (DPPH and ABTS) with IC50 values of 16.04 μM (DPPH) and 16.99 μM (ABTS), respectively. α-Amylase-IN-3 has good protein–ligand interactions profile against α-Amylase. α-Amylase-IN-3 may have pharmacological activities such as anti-oxidative, anti-inflammatory inhibitory, which is helpful for the development of diabetes and oxidative stress associated disease[1].

  • CAS Number: 93944-58-2
  • MF: C15H9NO4
  • MW: 267.24
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Edetol

Quadrol is an immunostimulant and has been implicated as a potentially useful agent in accelerated wound healing.

  • CAS Number: 102-60-3
  • MF: C14H32N2O4
  • MW: 292.415
  • Catalog: Inflammation/Immunology
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 369.1±0.0 °C at 760 mmHg
  • Melting Point: 32°C
  • Flash Point: 145.7±17.4 °C

UNII:5K6L8O868Y

4'-Hydroxyflavanone is an inhibitor of SREBP maturation and lipid synthesis. 4'-Hydroxyflavanone is a synthetic analogue of flavanone, has potential for hepatic steatosis and dyslipidemia research[1].

  • CAS Number: 6515-37-3
  • MF: C15H12O3
  • MW: 240.25
  • Catalog: Metabolic Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 447.5±45.0 °C at 760 mmHg
  • Melting Point: 182°C
  • Flash Point: 174.0±22.2 °C

1-epi-Regadenoson hydrazone

1-epi-Regadenoson hydrazone is an intermediate in the synthesis of αisomer impurity of Regadenoson which is a highly selective adenosine A2A receptor agonist[1].

  • CAS Number: 2015222-41-8
  • MF: C10H15N7O4
  • MW: 297.27
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-D-alanine N-hydroxy succinimide ester

Boc-D-Ala-OSu is an alanine derivative[1].

  • CAS Number: 34404-33-6
  • MF: C12H18N2O6
  • MW: 286.281
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MIF-IN-2

MIF-IN-2 is a migration inhibitory factor (MIF) inhibitor extracted from patent WO2021258272A1 compound 1. MIF-IN-2 can be used for the research of immune inflammation-related diseases[1].

  • CAS Number: 2756410-57-6
  • MF: C14H10ClN3O4
  • MW: 319.70
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

helospectin I

Helospectin I is a neuropeptide of the vasoactive intestinal peptide (VIP) family. Helospectin I has vasodilatory and antihypertensive activities, and decreases blood pressure. Helospectin I is originally isolated from the salivary gland venom of the lizard Heloderma suspectum[1][2].

  • CAS Number: 93438-37-0
  • MF: C183H293N47O59
  • MW:
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Rosiglitazone-d5 Maleate

Rosiglitazone-d5 (maleate) is the deuterium labeled Rosiglitazone maleate[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CTP Inhibitor

CTP inhibitor is a potent and selective CTP inhibitor. CTP inhibitor inhibits the plasma membrane citrate transporter (PMCT)[1].

  • CAS Number: 412940-35-3
  • MF: C13H9ClN2O6S
  • MW: 356.73800
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-Cys(Bzl)-OH

(R)-3-(Benzylthio)-2-((tert-butoxycarbonyl)amino)propanoic acid is a cysteine derivative[1].

  • CAS Number: 5068-28-0
  • MF: C15H21NO4S
  • MW: 311.397
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 481.2±45.0 °C at 760 mmHg
  • Melting Point: 86-88 °C
  • Flash Point: 244.8±28.7 °C