128427-86-1

128427-86-1 structure

Name: Sphingosine (d12:1)
Chemical Name: (2S,3R,4E)-2-amino-4-dodecene-1,3-diol
CAS Number: 128427-86-1
Molecular Formula: C₁₂H₂₅NO₂
Molecular Weight: 215.33200
Catalog: Research Areas Others
Create Date: 2018-04-22 16:35:26
Modify Date: 2025-09-27 16:53:28
C12-Sphingosine is a short-chain Sphingosine homologue. C12-Sphingosine inhibits serine palmitoyltransferase activity in primary cultured cerebellar cells[1].

Name	(2S,3R,4E)-2-amino-4-dodecene-1,3-diol
Synonyms	D-erythro-sphingosine C12-Sphingosine

Description	C12-Sphingosine is a short-chain Sphingosine homologue. C12-Sphingosine inhibits serine palmitoyltransferase activity in primary cultured cerebellar cells[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	C12-Sphingosine inhibits dr novo sphingosine and sphingolipid biosynthesis in murine cerebellar cells. C12-Sphingosine decreases serine palrnitoyltransferase activity in primary cultured neurons in a time- and concentration-dependent manner[1].
References	[1]. E C Mandon, et al. Sphingolipid biosynthesis in cultured neurons. Down-regulation of serine palmitoyltransferase by sphingoid bases. Eur J Biochem. 1991 Jun 15;198(3):667-74.