CTP Inhibitor
CTP Inhibitor structure
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Common Name | CTP Inhibitor | ||
|---|---|---|---|---|
| CAS Number | 412940-35-3 | Molecular Weight | 356.73800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C13H9ClN2O6S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of CTP InhibitorCTP inhibitor is a potent and selective CTP inhibitor. CTP inhibitor inhibits the plasma membrane citrate transporter (PMCT)[1]. |
| Name | 4-chloro-3-[(3-nitrophenyl)sulfamoyl]benzoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | CTP inhibitor is a potent and selective CTP inhibitor. CTP inhibitor inhibits the plasma membrane citrate transporter (PMCT)[1]. |
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| Related Catalog | |
| Target |
CTP[1] |
| References |
| Molecular Formula | C13H9ClN2O6S |
|---|---|
| Molecular Weight | 356.73800 |
| Exact Mass | 355.98700 |
| PSA | 137.67000 |
| LogP | 4.42420 |
| InChIKey | IIJQJWNGBILZCU-UHFFFAOYSA-N |
| SMILES | O=C(O)c1ccc(Cl)c(S(=O)(=O)Nc2cccc([N+](=O)[O-])c2)c1 |
| Storage condition | 2-8°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
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Mitochondrial and Plasma Membrane Citrate Transporters: Discovery of Selective Inhibitors and Application to Structure/Function Analysis.
Mol. Cell. Pharmacol. 2(3) , 101-110, (2010) Cytoplasmic citrate is the prime carbon source for fatty acid, triacylglycerol, and cholesterol biosyntheses, and also regulates glucose metabolism via its allosteric inhibition of phosphofructokinase... |
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Targeting mitochondrial citrate transport in breast cancer cell lines.
Anticancer Agents Med. Chem. 15(3) , 374-81, (2015) Lipogenesis is considered to be a very important aspect of cancer metabolism and targeting de novo lipid synthesis or related pathways are among novel approaches to treat cancer. Many targets of the p... |
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Spatio-temporal dynamics of replication and transcription sites in the mammalian cell nucleus.
Chromosoma 117(6) , 553-67, (2008) To study when and where active genes replicated in early S phase are transcribed, a series of pulse-chase experiments are performed to label replicating chromatin domains (RS) in early S phase and sub... |
| 4-Chloro-3-[[(3-nitrophenyl)amino]sulfonyl]-benzoic acid |
| 4-Chloro-3-(3-nitro-phenylsulfamoyl)-benzoic acid |
| CTP Inhibitor |