CTP Inhibitor

CTP Inhibitor Structure
CTP Inhibitor structure
Common Name CTP Inhibitor
CAS Number 412940-35-3 Molecular Weight 356.73800
Density N/A Boiling Point N/A
Molecular Formula C13H9ClN2O6S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Mitochondrial and Plasma Membrane Citrate Transporters: Discovery of Selective Inhibitors and Application to Structure/Function Analysis.

Mol. Cell. Pharmacol. 2(3) , 101-110, (2010)

Cytoplasmic citrate is the prime carbon source for fatty acid, triacylglycerol, and cholesterol biosyntheses, and also regulates glucose metabolism via its allosteric inhibition of phosphofructokinase. It originates either via the efflux of citrate from the m...

Targeting mitochondrial citrate transport in breast cancer cell lines.

Anticancer Agents Med. Chem. 15(3) , 374-81, (2015)

Lipogenesis is considered to be a very important aspect of cancer metabolism and targeting de novo lipid synthesis or related pathways are among novel approaches to treat cancer. Many targets of the pathway including ATP-citrate lyase (ACLY), acetyl-CoA carbo...

Spatio-temporal dynamics of replication and transcription sites in the mammalian cell nucleus.

Chromosoma 117(6) , 553-67, (2008)

To study when and where active genes replicated in early S phase are transcribed, a series of pulse-chase experiments are performed to label replicating chromatin domains (RS) in early S phase and subsequently transcription sites (TS) after chase periods of 0...