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4-氯-3-[[(3-硝基苯基)氨基]磺酰基]-苯甲酸

4-氯-3-[[(3-硝基苯基)氨基]磺酰基]-苯甲酸结构式
4-氯-3-[[(3-硝基苯基)氨基]磺酰基]-苯甲酸结构式
品牌特惠专场
常用名 4-氯-3-[[(3-硝基苯基)氨基]磺酰基]-苯甲酸 英文名 CTP Inhibitor
CAS号 412940-35-3 分子量 356.73800
密度 N/A 沸点 N/A
分子式 C13H9ClN2O6S 熔点 N/A
MSDS 中文版 美版 闪点 N/A
符号 GHS07
GHS07
信号词 Warning

Mitochondrial and Plasma Membrane Citrate Transporters: Discovery of Selective Inhibitors and Application to Structure/Function Analysis.

Mol. Cell. Pharmacol. 2(3) , 101-110, (2010)

Cytoplasmic citrate is the prime carbon source for fatty acid, triacylglycerol, and cholesterol biosyntheses, and also regulates glucose metabolism via its allosteric inhibition of phosphofructokinase. It originates either via the efflux of citrate from the m...

Targeting mitochondrial citrate transport in breast cancer cell lines.

Anticancer Agents Med. Chem. 15(3) , 374-81, (2015)

Lipogenesis is considered to be a very important aspect of cancer metabolism and targeting de novo lipid synthesis or related pathways are among novel approaches to treat cancer. Many targets of the pathway including ATP-citrate lyase (ACLY), acetyl-CoA carbo...

Spatio-temporal dynamics of replication and transcription sites in the mammalian cell nucleus.

Chromosoma 117(6) , 553-67, (2008)

To study when and where active genes replicated in early S phase are transcribed, a series of pulse-chase experiments are performed to label replicating chromatin domains (RS) in early S phase and subsequently transcription sites (TS) after chase periods of 0...