Modified Organosilica Core–Shell Nanoparticles for Stable pH Sensing in Biological Solutions

10.1021/acssensors.8b00034

2018-04-19

Continuous monitoring using nanoparticle-based sensors has been successfully employed in complex biological systems, yet the sensors still suffer from poor long-term stability partially because of the scaffold materials chosen to date. Organosilica core–shell...

Rationally Designed Sensing Selectivity and Sensitivity of an Aerolysin Nanopore via Site-Directed Mutagenesis

10.1021/acssensors.8b00021

2018-04-17

Selectivity and sensitivity are two key parameters utilized to describe the performance of a sensor. In order to investigate selectivity and sensitivity of the aerolysin nanosensor, we manipulated its surface charge at different locations via single site-dire...

Batch Fabrication of Ultrasensitive Carbon Nanotube Hydrogen Sensors with Sub-ppm Detection Limit

10.1021/acssensors.8b00006

2018-04-11

Carbon nanotube (CNT) has been considered as an ideal channel material for building highly sensitive gas sensors. However, the reported H2 sensors based on CNT always suffered from the low sensitivity or low production. We developed the technology to massivel...

Defected and Functionalized Germanene-based Nanosensors under Sulfur Comprising Gas Exposure

10.1021/acssensors.8b00167

2018-04-09

Efficient sensing of sulfur containing toxic gases like H2S and SO2 is of the utmost importance due to the adverse effects of these noxious gases. Absence of an efficient 2D-based nanosensor capable of anchoring H2S and SO2 with feasible binding and an appare...

Sensitivity-Tunable Colorimetric Detection of Chloropicrin Vapor on Nylon-6 Nanofibrous Membrane Based on a Detoxification Reaction with Biological Thiols

10.1021/acssensors.8b00135

2018-04-04

Detoxification reaction of chloropicrin in the human body with biological thiols was selected for detection of chloropicrin in the air. The consumption of free sulfhydryl group in biological thiols by chloropicrin is colorimetrically detectable with the addit...

Disposable MoS2-Arrayed MALDI MS Chip for High-Throughput and Rapid Quantification of Sulfonamides in Multiple Real Samples

10.1021/acssensors.8b00051

2018-04-02

In this work, we demonstrate, for the first time, the development of a disposable MoS2-arrayed matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) chip combined with an immunoaffinity enrichment method for high-throughput, rapid, and simu...

Determination of Gold Ions in Human Urine Using Genetically Engineered Microorganisms on a Paper Device

10.1021/acssensors.7b00931

2018-03-30

This paper presents a whole-cell biosensor that operates in conjunction with a smartphone-based fluorescence diagnostic system on a paper device to monitor the concentration of gold ions in human urine. The heavy metal-tolerant bacteria Cupriavidus metallidur...

Selective Determination of Cr(VI) by Glutaraldehyde Cross-Linked Chitosan Polymer Fluorophores

10.1021/acssensors.8b00038

2018-03-28

Selective determination of aquatic chromium is critically important because of the dramatic differences in health and environment impacts by trivalent and hexavalent forms of chromium; however, it is challenging. In this work, for the first time, a nonconjuga...

Ratiometric Fluorescent Biosensor for Visual Discrimination of Cancer Cells with Different Telomerase Expression Levels

10.1021/acssensors.8b00059

2018-03-26

Telomerase is inactive in normal somatic cells but highly activated in tumor cells to maintain their indefinite proliferation and immortal phenotype. As a specific marker for the generation and progress of almost all tumors, the detection of telomerase activi...

Michael Addition Based Chemodosimeter for Serum Creatinine Detection Using (E)-3-(Pyren-2-yl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one Chalcone

10.1021/acssensors.7b00822

2018-03-26

First, a simple and highly emissive fluorescent chalcone (E)-3-(pyren-2-yl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one (PTP) was synthesized via simple shaking along with an excellent quantum yield of 0.85, and proved as a stable, highly sensitive, and selecti...