A wellness study of 108 individuals using personal, dense, dynamic data clouds

10.1038/nbt.3870

2017-07-17

Longitudinal clinical and multi-omics data from 108 healthy individuals are analyzed to identify putative biomarkers and diagnostics of early disease states.

Nanoscale imaging of clinical specimens using pathology-optimized expansion microscopy

10.1038/nbt.3892

2017-07-17

Expansion microscopy, a technique for super-resolution imaging, is extended to clinical human tissue samples that are formalin fixed, paraffin embedded, stained and/or fresh frozen.

Wanted: biotech for an aging population

10.1038/nbt.3925

2017-07-12

Digital medicine's extraordinary ability to communicate with patients, especially in under-served communities, could help reorient the biotech industry to better address aging and its associated diseases.

An emerging model for life sciences commercialization

10.1038/nbt.3911

2017-07-12

There are challenges in transplanting the US–European technology transfer model to emerging economies.

Public biotech in 2016—the numbers

10.1038/nbt.3917

2017-07-12

The anticipated decline in the biotech industry's ability to raise capital from public investors and an accompanying slump in biotech markets materialized in 2016, but all is not gloom and doom.

CRISPR–Cas9 claim sets and the potential to stifle innovation

10.1038/nbt.3913

2017-07-12

Extremely broad claims surrounding Cas9 nucleases have the potential to stifle innovation in the field of genome editing.

Single-cell genomics for the masses

10.1038/nbt.3914

2017-07-12

Microbial communities are rapidly sequenced at the single-cell level using droplet microfluidics.

Algal oil productivity gets a fat bonus

10.1038/nbt.3920

2017-07-12

Partitioning of carbon to lipids is engineered to improve oil accumulation in an industrial alga.

Unlocking Big Data for better health

10.1038/nbt.3918

2017-07-12

As the volume of biomedical data being created grows, so does the need for data analytics training for life science researchers.

Long time-lapse nanoscopy with spontaneously blinking membrane probes

10.1038/nbt.3876

2017-07-03

Imaging cellular structures and organelles in living cells by long time-lapse super-resolution microscopy is challenging, as it requires dense labeling, bright and highly photostable dyes, and non-toxic conditions. We introduce a set of high-density, environm...