Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

DABCYL-LPETG-EDANS

DABCYL-LPETG-EDANS is a biological active peptide. (This 5-amino acid peptide is a sortase substrate, C-terminal sorting signal. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Sortases are a family of Gram-positive transpeptidases responsible for anchoring surface protein virulence factors to the peptidoglycan cell wall layer. Cleavage of this FRET substrate by sortase reveals the fluorescent signal, Abs/Em = 340/490 nm.)

  • CAS Number: 1807943-24-3
  • MF: C49H62N10O12S
  • MW: 1015.14
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

z-tyr-oh

Z-Tyr-OH is a tyrosine derivative[1].

  • CAS Number: 1164-16-5
  • MF: C17H17NO5
  • MW: 315.321
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 570.8±50.0 °C at 760 mmHg
  • Melting Point: 57-60 °C(lit.)
  • Flash Point: 299.0±30.1 °C

Lenalidomide-C10-OH

Lenalidomide-C10-OH (6a) is an intermediate in the synthesis of INY-03-041[1].

  • CAS Number: 2503018-12-8
  • MF: C23H32N2O4
  • MW: 400.51
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Arctigenin 4'-O-beta-gentiobioside

Arctigenin 4'-O-β-gentiobioside is a natural compound isolated from Arctigenin.

  • CAS Number: 41682-24-0
  • MF: C33H44O16
  • MW: 696.693
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 926.1±65.0 °C at 760 mmHg
  • Melting Point: 174-176 °C
  • Flash Point: 291.0±27.8 °C

1-Hydroxycanthin-6-one

1-Hydroxycanthin-6-one is an alkaloid that can be found in Ailanthus giraldii[1].

  • CAS Number: 80787-59-3
  • MF: C14H8N2O2
  • MW: 236.225
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 476.3±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 241.9±28.7 °C

TY-51469

TY-51469 is a chymase inhibitor with IC50s for simian and human chymases of 0.4 and 7.0 nM, respectively.

  • CAS Number: 603987-59-3
  • MF: C20H15FN2O6S4
  • MW: 526.60
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-2-(Hydroxyethyl)-L-valine-d4

N-2-(Hydroxyethyl)-L-valine-d4 is the deuterium labeled N-2-(Hydroxyethyl)-L-valine[1].

  • CAS Number: 120398-50-7
  • MF: C7H11D4NO3
  • MW: 165.22400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(15R)-12-Hydroxy-15-methyllycopodan-5-one

Lycodoline is a alkaloid with butyrylcholinesterase (BChE) (IC50 of 667 μM) inhibition activities[1].

  • CAS Number: 6900-92-1
  • MF: C16H25NO2
  • MW: 263.375
  • Catalog: Neurological Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 412.7±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 203.4±28.7 °C

4-Pentyl(O-2H5)phenol

4-Pentylphenol-d5 is the deuterium labeled 4-Pentylphenol[1].

  • CAS Number: 126839-95-0
  • MF: C11H11D5O
  • MW: 169.275
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 250.5±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 135.0±8.8 °C

DAPOA

DAPOA is a click chemistry reagent containing an azide group. DAPOA can be used in peptide synthesis as a linker that can be further modified at the azido-groups using Staudinger ligation or click-chemistry[1].

  • CAS Number: 2389064-43-9
  • MF: C5H8N6O3
  • MW: 200.16
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tetrachloroveratrole

Tetrachloroveratrole is one of the biodegradation products of bacterial O-methylation of Tri- and Tetra chloroguaiacols. The Tri- and Tetra chloroguaiacols are formed during bleaching of wood pulp in the paper manufacturing industry[1].

  • CAS Number: 944-61-6
  • MF: C8H6Cl4O2
  • MW: 275.94400
  • Catalog: Others
  • Density: 1.489g/cm3
  • Boiling Point: 318.5ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 122.1ºC

Secretin (human)

Secretin (28-54), human is a 27-amino acid residue C-terminally amidated peptide, which acts on secretin receptors.

  • CAS Number: 108153-74-8
  • MF: C130H220N44O40
  • MW: 3039.409
  • Catalog: Peptides
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ganoapplanoid F

Ganoapplanoid F, a highly oxygenated lanostane triterpenoid from Ganoderma applanatum, inhibits lipid accumulation in adipocytes. Ganoapplanoid F can be used for the research of obesity[1].

  • CAS Number: 2758812-34-7
  • MF: C29H38O10
  • MW: 546.61
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LyP-2

LyP-2 is a peptide that homes to tumor lymphatics. LyP2 homes to lymphatics of C8161 melanomas and cervical carcinomas and K14-HPV16 skin, but not to MDA-MB435 tumors, showing heterogeneity in the molecular markers of tumor cells and lymphatics[1].

  • CAS Number: 850859-24-4
  • MF: C37H69N17O12S2
  • MW: 1008.18
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Formyl-L-leucine

N-Formyl-L-leucine is a leucine derivative[1].

  • CAS Number: 6113-61-7
  • MF: C7H13NO3
  • MW: 159.183
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 360.6±25.0 °C at 760 mmHg
  • Melting Point: 142 °C
  • Flash Point: 171.9±23.2 °C

Maohuoside A

Maohuoside A, a single compound isolated from the E. koreanum that potently promotes osteogenesis. Maohuoside A enhances the osteogenesis of bone marrow-derived mesenchymal stem cells via bone morphogenetic protein (BMP) and MAPK signaling pathways[1][2].

  • CAS Number: 128988-55-6
  • MF: C27H32O12
  • MW: 548.536
  • Catalog: Metabolic Disease
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 838.2±65.0 °C at 760 mmHg
  • Melting Point: 222-224℃
  • Flash Point: 278.8±27.8 °C

LL-37 RKS trifluoroacetate salt

LL-37 RKS is an active fragment of LL-37[1].

  • CAS Number: 672345-61-8
  • MF: C169H292N54O45
  • MW:
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Cyclopropyl-4-iodobenzamide

N-Cyclopropyl-4-iodobenzamide is an active molecule.

  • CAS Number: 794539-14-3
  • MF: C10H10INO
  • MW: 287.09697
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 389.9±25.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 189.6±23.2 °C

umuhengerin

Umuhengerin is a methoxylated flavone. Umuhengerin can be isolated from Cardiospermum corindum L[1].

  • CAS Number: 29215-55-2
  • MF: C20H20O8
  • MW: 388.36800
  • Catalog: Others
  • Density: 1.304g/cm3
  • Boiling Point: 581.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 205.9ºC

Anti-osteoporosis agent-7

Anti-osteoporosis agent-7 (Compound 133) is a potential anti-osteoporosis agent showing high inhibition of osteoclast formation.

  • CAS Number: 445254-59-1
  • MF: C18H19Cl2NO3
  • MW: 368.25
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 514.4±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 264.9±30.1 °C

Odorinol

Odorinol is a natural product isolated from branches and leaves of Aglaia odorata. Odorinol has potential antineoplastic activity and can inhibit both the initiation and promotion stages of skin cancer[1].

  • CAS Number: 72755-22-7
  • MF: C18H24N2O3
  • MW: 316.39
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 588.6±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 309.8±30.1 °C

Atisnolerbart

Atisnolerbart is a human IgG4 antibody targeting BETVIA, the major birch pollen allergen Bet v 1-A.

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,5-Dichloro-2,4-dinitrobenzene-13C6

1,5-Dichloro-2,4-dinitrobenzene-13C6 is the 13C labeled 1,5-Dichloro-2,4-dinitrobenzene[1].

  • CAS Number: 335081-12-4
  • MF: C6H2Cl2N2O4
  • MW: 243.05
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-D-LYS(Z)-OH

H-D-Lys(Z)-OH is a lysine derivative[1].

  • CAS Number: 34404-32-5
  • MF: C14H20N2O4
  • MW: 280.320
  • Catalog: Others
  • Density: 1.206g/cm3
  • Boiling Point: 499.6±45.0 °C at 760 mmHg
  • Melting Point: 229℃
  • Flash Point: 255.9±28.7 °C

MO-I-500

MO-I-500 is a pharmacological of FTO inhibitor with an IC50 of 8.7 μM for the inhibition of purified FTO demethylase catalyzing demethylation of an artificial small methylated substrate. MO-I-500 can be used for the research of rare panresistant triple-negative inflammatory breast cancer[1].

  • CAS Number: 1585219-04-0
  • MF: C12H12ClNO5S
  • MW: 317.75
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Ethylhexyl acetate-d17

2-Ethylhexyl acetate-d17 is the deuterium labeled 2-Ethylhexyl acetate[1].

  • CAS Number: 1219802-70-6
  • MF: C10H20O2
  • MW: 172.265
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 195.7±8.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 71.4±8.3 °C

1-Boc-4-oxo-D-proline benzyl ester

1-Boc-4-oxo-D-proline benzyl ester is a proline derivative, it can be used for the synthesis of compounds[1].

  • CAS Number: 224627-26-3
  • MF: C17H21NO5
  • MW: 319.35
  • Catalog: Others
  • Density: 1.219±0.06 g/cm3(Predicted)
  • Boiling Point: 439.9±45.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

Ac-Pro-Leu-Gly-OH

Ac-Pro-Leu-Gly-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 89626-38-0
  • MF: C15H25N3O5
  • MW: 327.38
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-(azidomethyl)pyrene

1-(Azidomethyl)pyrene is a fluorescent dye[1].

  • CAS Number: 1006061-57-9
  • MF: C17H11N3
  • MW: 257.28900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 68 °C
  • Flash Point: N/A

α-Amylase

α-Amylase from Aspergillus oryzae is an amylase. α-Amylase from Aspergillus oryzae can be used for various biochemical studies[1].

  • CAS Number: 9001-19-8
  • MF: C9H14N4O3
  • MW: 226.232
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 656.2±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 350.7±31.5 °C