Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

(R)-2-Amino-2-(4-fluorophenyl)acetic acid hydrochloride

(R)-2-Amino-2-(4-fluorophenyl)acetic acid hydrochloride is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 144744-41-2
  • MF: C8H9ClFNO2
  • MW: 205.61400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 321.2ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 148.1ºC

Endokinin C

Endokinin C is a peptide component of endokinin. Endokinin C works as a neurotransmitter or modulator in the pain system. Pretreatment with endokinin C prevents induction of scratching behavior and thermal hyperalgesia of endokinin A/B in mice[1].

  • CAS Number: 347837-74-5
  • MF: C78H122N20O21
  • MW: 1675.92
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(S)-methyl 2-((S)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanoate

(S)-methyl 2-((S)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanoate is a phenylalanine derivative[1].

  • CAS Number: 1140908-89-9
  • MF: C32H44N4O6
  • MW: 566.688
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 827.4±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 454.2±34.3 °C

CiMiraceMoside D

Cimiracemoside D is a natural product found in Actaea racemosa with unknown details.

  • CAS Number: 290821-39-5
  • MF: C37H58O11
  • MW: 678.850
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 773.3±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 234.7±26.4 °C

1,4-Bis(1,3-benzodioxole-5-yl)tetrahydro-1H,3H-furo[3,4-c]furan

DL-Asarinin (compound 88) is a natural product that can be found in waste leaves of Cinnamomum camphora[1].

  • CAS Number: 7076-24-6
  • MF: C20H18O6
  • MW: 354.35300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Drahebenine

Drahebenineis animidazole alkaloidthatcan be found in Dracocephalum heterophyllum[1].

  • CAS Number: 1399049-43-4
  • MF: C13H16N2O2
  • MW: 232.28
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

dl-2-methylglutamic acid

DL-2-Methylglutamic Acid Hemihydrate is a glutamic acid derivative[1].

  • CAS Number: 71-90-9
  • MF: C6H11NO4
  • MW: 161.15600
  • Catalog: Adrenergic Receptor
  • Density: N/A
  • Boiling Point: 329.3ºC at 760 mmHg
  • Melting Point: 160ºC (dec.)(lit.)
  • Flash Point: 153ºC

Azathioprine-d3

Azathioprine-d3 (BW 57-322-d3) is the deuterium labeled Azathioprine (HY-B0256). Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis[1].

  • CAS Number: 2702733-53-5
  • MF: C9H4D3N7O2S
  • MW: 280.28
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CER5-2’R-d9

CER5-2’R-d9 is deuterium labeled CER5-2’R.

  • CAS Number: 2260670-31-1
  • MF: C34H58D9NO4
  • MW: 562.96
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

8-Azidoadenosine 3':5'-cyclic monophosphate

8-Azido-cAMP is a fluorescent cAMP analog, acting as the model target of detecting cAMP[1].

  • CAS Number: 31966-52-6
  • MF: C10H11N8O6P
  • MW: 370.21800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Benzo[b]thiophene-2-carboximidamide, 4-fluoro-N-hydroxy-5,6-dimethoxy-

Benzo[b]thiophene-2-carboximidamide, 4-fluoro-N-hydroxy-5,6-dimethoxy- is an orally available compound suitable for the treatment of heart failure without inducing nausea, vomiting and restlessness.

  • CAS Number: 142648-47-3
  • MF: C11H11FN2O3S
  • MW: 270.28
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

taraxasterol acetate

Taraxasteryl acetate is isolated from P. sagittalis,and has a broad spectrum of anti-inflammatory activity. Taraxasteryl acetate relieves dextran, zymosan and arachidonic acid induced rat hind-paw edema. Taraxasteryl acetate can be used for the topical inflammation treatment[1].

  • CAS Number: 6426-43-3
  • MF: C32H52O2
  • MW: 468.754
  • Catalog: Inflammation/Immunology
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 502.8±19.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 254.8±9.0 °C

Somatostatin-14 (3-14)

Somatostatin-14 (3-14) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 54518-51-3
  • MF: C71H96N16O17S2
  • MW: 1509.75
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hyaluronidase

Hyaluronidase (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is a naturally occurring enzyme that depolymerizes hyaluronic acid by cleavage of glycosidic bonds and has been used as a local anesthetic additive[1][2].

  • CAS Number: 37326-33-3
  • MF: C18H14O7
  • MW: 342.300
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 598.6±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 223.2±23.6 °C

1-bromoheptane-d15

1-Bromoheptane-d15 is the deuterium labeled 1-Bromoheptane[1].

  • CAS Number: 98195-42-7
  • MF: C7BrD15
  • MW: 194.19000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Thymopoietin II: 32-34

Thymotrinan (RGH-0205) is a biologically active fragment of the naturally occurring thymus hormone thymopoietin and a immunomodulating peptide. Thymotrinan exerts similar immunomodulatory activities to TP5 and to affect humoral as well as cellular responses[1].

  • CAS Number: 85465-82-3
  • MF: C16H31N7O6
  • MW: 417.46100
  • Catalog: Inflammation/Immunology
  • Density: 1.51g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hexane-1,6-diol-d4

Hexane-1,6-diol-d4 is the deuterium labeled Hexane-1,6-diol[1].

  • CAS Number: 6843-76-1
  • MF: C6H10D4O2
  • MW: 122.19900
  • Catalog: Others
  • Density: 0.997g/cm3
  • Boiling Point: 239.673ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 101.667ºC

Clozic

Clozic is a potential anti-arthritic agent.

  • CAS Number: 22494-47-9
  • MF: C17H17ClO3
  • MW: 304.76800
  • Catalog: Inflammation/Immunology
  • Density: 1.218g/cm3
  • Boiling Point: 472ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 239.2ºC

Pyridoxal 5'-​phosphate monohydrate

Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phosphate (PMP)[1][2].

  • CAS Number: 41468-25-1
  • MF: C8H12NO7P
  • MW: 265.157
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 565.7ºC at 760 mmHg
  • Melting Point: 140-143 °C(lit.)
  • Flash Point: 296ºC

Acridine Orange hydrochloride

Acridine orange is a cell-permeable fluorescent dye that binds to nucleic acids, resulting in an altered spectral emission.

  • CAS Number: 65-61-2
  • MF: C17H20ClN3
  • MW: 301.81400
  • Catalog: Dye Reagents
  • Density: 1.001 g/mL at 20ºC
  • Boiling Point: 468.6ºC at 760 mmHg
  • Melting Point: 284-287ºC(lit.)
  • Flash Point: 237.2ºC

Quercetin 3-O-beta-D-glucose-7-O-beta-D-gentiobioside

Quercetin-3-O-β-D-glucose-7-O-β-D-gentiobiosiden is a flavonoid from Quercetin.

  • CAS Number: 60778-02-1
  • MF: C33H40O22
  • MW: 788.657
  • Catalog: Others
  • Density: 1.9±0.1 g/cm3
  • Boiling Point: 1189.6±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 371.7±27.8 °C

LRRKtide

LRRKtide is a substrate for LRRK kinase[1].

  • CAS Number: 1071466-49-3
  • MF: C83H147N31O22
  • MW: 1931.25
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

handelin

Handelin is a guaianolide dimer from Chrysanthemum boreale that has potent anti-inflammatory activity by down-regulating NF-κB signaling and pro-inflammatory cytokine production[1].

  • CAS Number: 62687-22-3
  • MF: C32H40O8
  • MW: 552.655
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 731.0±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 236.3±26.4 °C

Withanolide A

Withanolide A, isolated from the indian herbal drug Ashwagandha (root of Withania somnifera), could regenerate neurites and reconstruct synapses in severely damaged neurons[1].

  • CAS Number: 32911-62-9
  • MF: C28H38O6
  • MW: 470.59800
  • Catalog: Neurological Disease
  • Density: 1.264
  • Boiling Point: 651.6±55.0 °C(Predicted)
  • Melting Point: 305℃ (DEC.)
  • Flash Point: N/A

AZD8329

AZD8329 is a potent 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 9 nM for human 11β-HSD1, displays excellent selectivity versus 11β-HSD2, 17β-HSD1 and 17β-HSD3[1].

  • CAS Number: 1048668-70-7
  • MF: C25H31N3O3
  • MW: 421.53200
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tanshindiol A

Tanshindiol A is a natural product[1].

  • CAS Number: 97411-46-6
  • MF: C18H16O5
  • MW: 312.3
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Ethylaniline-d5

3-Ethylaniline-d5 is the deuterium labeled 3-Ethylaniline (HY-W010482). 3-Ethylaniline is metabolized in vivo to electrophilic intermediates that covalently bind to DNA and that adducts are formed in the DNA of bladder. 3-Ethylaniline can be used for the research of bladder cancer[1][2].

  • CAS Number: 1643538-19-5
  • MF: C8H6D5N
  • MW: 126.21044889
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TC SL C5

MALAT1-IN-1 (compounds 5) is a potent and specific Malat1 (Metastasis-associated lung adenocarcinoma transcript 1) inhibitor. MALAT1-IN-1 modulated Malat1 downstream genes in a dose-dependent manner without affecting expression of nuclear enriched abundant transcript 1 (Neat1) [1].

  • CAS Number: 827327-28-6
  • MF: C19H21N3O2
  • MW: 323.39
  • Catalog: Cancer
  • Density: 1.14±0.1 g/cm3(Predicted)
  • Boiling Point: 534.0±60.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

6H-Indolo(3,2,1-de)(1,5)naphthyridin-6-one

Canthin-6-one displays a wide range of biological activities, such as antimycobacterial activity[1].

  • CAS Number: 479-43-6
  • MF: C14H8N2O
  • MW: 220.23
  • Catalog: Inflammation/Immunology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 346.5±34.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 163.4±25.7 °C

Methylkushenol C

Methylkushenol C is a phenolic substance. Methylkushenol C can be isolated from Sophora flavescens[1].

  • CAS Number: 128879-52-7
  • MF: C26H28O7
  • MW: 452.50
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A