Thymopoietin II: 32-34

Modify Date: 2025-08-25 15:59:46

Thymopoietin II: 32-34 Structure
Thymopoietin II: 32-34 structure
 Common Name Thymopoietin II: 32-34
CAS Number 85465-82-3 Molecular Weight 417.46100
Density 1.51g/cm3 Boiling Point N/A
Molecular Formula C16H31N7O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thymopoietin II: 32-34


Thymotrinan (RGH-0205) is a biologically active fragment of the naturally occurring thymus hormone thymopoietin and a immunomodulating peptide. Thymotrinan exerts similar immunomodulatory activities to TP5 and to affect humoral as well as cellular responses[1].

 Names

Name (2S)-2-[[(2S)-6-amino-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]butanedioic acid
Synonym More Synonyms

 Thymopoietin II: 32-34 Biological Activity

Description Thymotrinan (RGH-0205) is a biologically active fragment of the naturally occurring thymus hormone thymopoietin and a immunomodulating peptide. Thymotrinan exerts similar immunomodulatory activities to TP5 and to affect humoral as well as cellular responses[1].
Related Catalog
References

[1]. Heizmann J, et al. Enzymatic cleavage of thymopoietin oligopeptides by pancreatic and intestinal brush-border enzymes. Peptides. 1996;17(7):1083-1089.

 Chemical & Physical Properties

Density 1.51g/cm3
Molecular Formula C16H31N7O6
Molecular Weight 417.46100
Exact Mass 417.23400
PSA 246.74000
LogP 0.60820
Index of Refraction 1.633

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CI9099033
CHEMICAL NAME :
L-Aspartic acid, N-(N(sup 2)-L-arginyl-L-lysyl)-
CAS REGISTRY NUMBER :
85465-82-3
LAST UPDATED :
199407
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C16-H31-N7-O6
MOLECULAR WEIGHT :
417.54

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 11,764,1986
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 11,764,1986
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 11,764,1986

 Synonyms

Rgh 0205
Thymotrinanum [INN-Latin]
Arg-Lys-Asp
Thymotrinanum
N-(N(sup 2)-L-Arginyl-L-lysyl)-L-aspartic acid
Timotrinan
Timotrinan [INN-Spanish]
L-Aspartic acid,N-(N(sup 2)-L-arginyl-L-lysyl)
Thymotrinan
Thymopoietin II: 32-34
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