Hyaluronidase

Modify Date: 2024-01-04 19:23:59

Hyaluronidase Structure
Hyaluronidase structure
Common Name Hyaluronidase
CAS Number 37326-33-3 Molecular Weight 342.300
Density 1.5±0.1 g/cm3 Boiling Point 598.6±50.0 °C at 760 mmHg
Molecular Formula C18H14O7 Melting Point N/A
MSDS Chinese USA Flash Point 223.2±23.6 °C

 Use of Hyaluronidase


Hyaluronidase (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is a naturally occurring enzyme that depolymerizes hyaluronic acid by cleavage of glycosidic bonds and has been used as a local anesthetic additive[1][2].

 Names

Name Hyaluronidase
Synonym More Synonyms

 Hyaluronidase Biological Activity

Description Hyaluronidase (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is a naturally occurring enzyme that depolymerizes hyaluronic acid by cleavage of glycosidic bonds and has been used as a local anesthetic additive[1][2].
Related Catalog
References

[1]. Vartanian AJ, et al. Injected hyaluronidase reduces restylane-mediated cutaneous augmentation. Arch Facial Plast Surg. 2005 Jul-Aug;7(4):231-7.

[2]. Brandon E, et al. The Use of Hyaluronidase in Cosmetic Dermatology: A Review of the Literature. J Clin Investigat Dermatol. 2015;3(2): 7.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 598.6±50.0 °C at 760 mmHg
Molecular Formula C18H14O7
Molecular Weight 342.300
Flash Point 223.2±23.6 °C
Exact Mass 342.073944
LogP 2.41
Appearance of Characters powder | yellow-brown
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.642
Storage condition −20°C
Water Solubility Soluble in water, practically insoluble in acetone and in anhydrous ethanol

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
WGK Germany 3

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 Synonyms

2,4-Bis(1,3-benzodioxol-5-yl)-4-oxobutanoic acid
Neopermease
1,3-Benzodioxole-5-butanoic acid, α-1,3-benzodioxol-5-yl-γ-oxo-
Hydase
EINECS 253-464-3
Hyaluronoglucosidase
MFCD00131351
Hyaluronoglucosaminidase
Chondroitinase
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