Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

H-Gly-Asp-OH

Gly-Asp is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 4685-12-5
  • MF: C6H10N2O5
  • MW: 190.15400
  • Catalog: Others
  • Density: 1.499 g/cm3
  • Boiling Point: 468.7ºC at 760 mmHg
  • Melting Point: ~205 °C
  • Flash Point: 237.3ºC

Spermine(N3BBB)

Spermine(N3BBB) is a click chemistry reagent containing an azide group and can be used for various biochemical studies[1].

  • CAS Number: 1190203-80-5
  • MF: C25H48N6O6
  • MW: 528.69
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Methylisopelletierine

Methylisopelletierine is the immediate precursor of psueudopelletierine. Methylisopelletierine is derived from lysine and acetate[1].

  • CAS Number: 18747-42-7
  • MF: C9H17NO
  • MW: 155.237
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 216.9±13.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 66.9±9.2 °C

Z-D-ARG-OH

Z-D-Arg-OH is an arginine derivative[1].

  • CAS Number: 6382-93-0
  • MF: C14H20N4O4
  • MW: 308.333
  • Catalog: Others
  • Density: 1.33 g/cm3
  • Boiling Point: N/A
  • Melting Point: 168-171ºC
  • Flash Point: N/A

Epimedin I

Korepimedoside C (Epimedin I), a flavonol glycoside, is isolated from the aerial parts of Epimedium koreanum Nakai. Epimedium koreanum Nakai is a famous Chinese herbal medicine for the research of impotence, osteoporosis, immune suppression and cardiovascular diseases[1][2].

  • CAS Number: 205445-00-7
  • MF: C41H52O21
  • MW: 880.84
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Arg-Asp-OH

Arginylaspartic acid is a biologically active peptide.

  • CAS Number: 15706-88-4
  • MF: C12H23N5O7
  • MW: 349.34000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-[4-(2-Aminoethyl)-2-iodophenoxy]phenol Hydrochloride

3-Iodothyronamine (hydrochloride) is an endogenous and rapid-acting derivative of thyroid hormone. 3-Iodothyronamine potently activates an orphan G protein-coupled receptor in vitro (TAAR1) and induced hypothermia in vivo on a rapid time scale. 3-Iodothyronamine can be used for the research of congestive heart failure[1].

  • CAS Number: 788824-64-6
  • MF: C14H15ClINO2
  • MW: 391.63
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 209-211ºC
  • Flash Point: N/A

5α-reductase-IN-1

5α-reductase-IN-1 is an inhibitor of 5α-reductase, used for the research of patterned alopecia in combination with minoxidil.

  • CAS Number: 119348-12-8
  • MF: C31H37NO5
  • MW: 503.62918
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Zinc stearate

Zinc stearate is a Zinc distearate. Zinc stearate can be used as an excipient, such as lubricants for tablets and capsules. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

  • CAS Number: 557-05-1
  • MF: C36H70O4Zn
  • MW: 632.32
  • Catalog: Others
  • Density: 1.095
  • Boiling Point: 359.4ºC at 760 mmHg
  • Melting Point: 128-130 °C (lit.)
  • Flash Point: 180℃

Terminal Deoxynucleotidyl Transferase

Terminal deoxyribonucleotidyltransferase (TdT) catalyses the condensation of deoxyribonucleotide triphosphates onto the 3' hydroxyl ends of DNA strands and adds N-regions to gene segment junctions during V(D)J recombination. Terminal deoxyribonucleotidyltransferase is expressed in immature, pre-B, pre-T lymphoid cells, and acute lymphoblastic leukemia/lymphoma cells[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,2-Dichloro-4,5-dimethoxybenzene

4,5-Dichloroveratrole is a chlorinated product formed by reaction of Veratryl alcohol (VE; HY-107858) with chlorine dioxide solution[1].

  • CAS Number: 2772-46-5
  • MF: C8H8Cl2O2
  • MW: 207.054
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 257.1±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 98.8±26.0 °C

D-NMAPPD

D-NMAPPD ((1R,2R)-B13) is an acid ceramidase inhibitor. D-NMAPPD regulates NMDA receptor properties by enhancing endogenous production of ceramides. D-NMAPPD has anticancer effecs[1][2].

  • CAS Number: 35922-06-6
  • MF: C23H38N2O5
  • MW: 422.558
  • Catalog: Cancer
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 636.2±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 338.6±31.5 °C

Aprepitant-d4

Aprepitant-d4 is the deuterium labeled Aprepitant[1].

  • CAS Number: 1133387-60-6
  • MF: C23H17D4F7N4O3
  • MW: 538.45100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 242-244°C
  • Flash Point: N/A

Angiotensin (1-12) (human) trifluoroacetate salt

Angiotensin (1-12) (human) is an endogenous substrate for the production of biologically active angiotensin peptides by a non-renin-dependent mechanism[1].

  • CAS Number: 136865-09-3
  • MF: C73H109N19O16
  • MW: 1508.764
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Gastric Inhibitory Polypeptide (6-30) amide (human) trifluoroacetate salt

Gastric Inhibitory Polypeptide (6-30) amide (human) is an incretin hormone. Gastric Inhibitory Polypeptide (6-30) amide (human) can be used for the research of diabete[1].

  • CAS Number: 1139691-72-7
  • MF: C139H209N35O38S
  • MW: 3010.424
  • Catalog: Metabolic Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 2775.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 1632.2±34.3 °C

Todralazine

Todralazine is capable of reducing blood pressure preferentially in hypertension.

  • CAS Number: 14679-73-3
  • MF: C11H12N4O2
  • MW: 232.23900
  • Catalog: Cardiovascular Disease
  • Density: 1.328g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sennoside C

Sennoside C is an anthraquinone glycoside, found in leaves and pods of Senna (Cassia angustifolia)[1].

  • CAS Number: 37271-16-2
  • MF: C42H40O19
  • MW: 848.756
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 1130.3±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 344.4±27.8 °C

Quercetin 3-O-beta-D-glucosyl-(1->2)-rhamnoside

Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside is main antioxidant from Shuxuening, an herbal medicines injection[1].

  • CAS Number: 143016-74-4
  • MF: C27H30O16
  • MW: 610.518
  • Catalog: Cardiovascular Disease
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 987.1±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 326.7±27.8 °C

Magnocurarine

Magnocurarine a natural compound isolated from Tiliacora racemosa[1].

  • CAS Number: 6801-40-7
  • MF: C19H24NO3
  • MW: 314.398
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 199-200 ºC
  • Flash Point: N/A

Boc-D-Phe-OH

Boc-D-Phe-OH is a phenylalanine derivative[1].

  • CAS Number: 18942-49-9
  • MF: C14H19NO4
  • MW: 265.305
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 426.6±38.0 °C at 760 mmHg
  • Melting Point: 85-88ºC
  • Flash Point: 211.8±26.8 °C

CalFluor 488 Azide

CalFluor 488 Azide is a water-soluble fluorogenic azide probe. CalFluor 488 Azide is activated by Cu-catalyzed or metal-free click reaction. CalFluor 488 Azide is not fluorescent until it is reacted with alkynes[1][2].

  • CAS Number: 1798305-98-2
  • MF: C37H49N5O13S2
  • MW: 835.94
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Macropa-NH2

Macropa-NH2, a H2macropa derivative with an macrocyclic core of macropa, can be used in targeted cancer therapy research[1].

  • CAS Number: 2146095-13-6
  • MF: C26H37N5O8
  • MW: 547.60
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Momordicoside F1

Momordicoside F1 is a triterpenoid that can be isolated from Momordica charantia[1].

  • CAS Number: 81348-81-4
  • MF: C37H60O8
  • MW: 632.87
  • Catalog: Others
  • Density: 1.20±0.1 g/cm3
  • Boiling Point: 711.4±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: N/A

2,4,6,6-tetramethyl-3(6H)-pyridone

2,4,6,6-Tetramethyl-3(6H)-pyridinone is a natural product that can be isolated from the tropical marine sponge Agelas oroides[1].

  • CAS Number: 203524-64-5
  • MF: C9H13NO
  • MW: 151.206
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 212.7±33.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 81.1±30.7 °C

p-Nitrophenyl 2-O-(b-L-Fucopyranosyl)-b-D-galactopyranoside

4-Nitrophenyl 2-O-(β-L-Fucopyranosyl)-β-D-Galactopyranoside is a synthetic chromogenic substrate and can be used in the assay of α-fucosidases which hydrolyze the glycosidic linkage Fuc α1-2Gal. The assay is based on the sequential action of α-fucosidase and an exogenously added exo-β-d-galactosidase to release the easily measurable p-nitrophenol moiety[1].

  • CAS Number: 77640-21-2
  • MF: C18H25NO12
  • MW: 447.39100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 233-236ºC dec.
  • Flash Point: N/A

Phenylethynylcarbinol carbamate

Phenylethynylcarbinol carbamate is a hypnotic agent[1].

  • CAS Number: 3567-38-2
  • MF: C10H9NO2
  • MW: 175.18400
  • Catalog: Neurological Disease
  • Density: 1.192g/cm3
  • Boiling Point: 320.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 165.2ºC

JF646, SE

JF646, SE (JF646, NHS), a red fluorescent dye, is supplied as an NHS ester for coupling to primary amine groups. JF646, SE is suitable for confocal fluorescent imaging, super resolution microscopy (SRM) techniques such as dSTORM (live and fixed cells) and STED imaging. JF646, SE is also suitable for flow cytometry.

  • CAS Number: 1811539-59-9
  • MF: C33H31N3O6Si
  • MW: 593.701
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cyclohexyl [3,5-bis(methylthio)-4-isothiazolyl]carbamate

Cyclohexyl [3,5-bis(methylthio)-4-isothiazolyl]carbamate is a compound that can be used for altering the lifespan of eukaryotic organisms[1].

  • CAS Number: 311334-13-1
  • MF: C12H18N2O2S3
  • MW: 318.48
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Obafistat

Obafistat is a potent aldo-keto reductase AKR1C3 inhibitor with an IC50 of 1.2 nM for human AKR1C3 (patent WO2017202817A1, example 4)[1].

  • CAS Number: 2160582-57-8
  • MF: C15H16FN5O3S
  • MW: 365.38
  • Catalog: Inflammation/Immunology
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 623.3±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 330.8±34.3 °C

Gal-C4-Chol

Gal-C4-Chol is a glycosylated cholesterol derivative. Gal-C4-Chol can be used as a ligand for asialoglycoprotein receptors (ASGPR) to prepare Galactosylated (Gal) liposomes. Gal-C4-Chol can be used to prepare simple lipid-based nanoparticles[1][2][3].

  • CAS Number: 219850-70-1
  • MF: C40H69N3O7S
  • MW: 736.06
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A