Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Epsilon-momfluorothrin

Epsilon-momfluorothrin is a type I synthetic pyrethroid insecticide, activates constitutive androstane receptor (CAR), and induces hepatocellular tumors in rats[1].

  • CAS Number: 1065124-65-3
  • MF: C19H19F4NO3
  • MW: 385.35
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(+)-Clopidogrel bisulfate

Clopidogrel sulfate is an antiplatelet agent. Specifically, Clopidogrel sulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. Clopidogrel sulfate can be used for research of heart disease and stroke[1].

  • CAS Number: 135046-48-9
  • MF: C16H18ClNO6S2
  • MW: 419.900
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: 423.7ºC at 760 mmHg
  • Melting Point: 184ºC
  • Flash Point: 210ºC

2,4-Dimethylaniline-d6 hydrochloride

2,4-Dimethylaniline-d6 (hydrochloride) is the deuterium labeled 2,4-Dimethylaniline hydrochloride[1].

  • CAS Number: 1219805-38-5
  • MF: C8H6D6ClN
  • MW: 163.68
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Methyl-8-(2-deoxy-b-D-ribofuranosyl)isoxanthopterin

guanosine analogue. 3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin is widely used in studies of DNA binding and dynamics, with an absorbance maximum at 350 nm and an emission maximum at 430 nm[1].

  • CAS Number: 170379-51-8
  • MF: C12H15N5O5
  • MW: 309.27800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Chamaejasmenin A

Chamaejasmenin A is a C-3/C-3’’ linkage biflavanone that can be isolated from Stellera chamaejasme L.[1].

  • CAS Number: 89618-14-4
  • MF: C32H26O10
  • MW: 570.54300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(2E,6E)-3,7-Dimethyltrideca-2,6-dien-12-yn-1-ol

(2E,6E)-3,7-Dimethyltrideca-2,6-dien-12-yn-1-ol is a isoprenoid analogue[1].

  • CAS Number: 2361137-98-4
  • MF: C15H24O
  • MW: 220.35
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Territrem A

Territrem A is a shock-causing mycotoxin isolated from Aspergillus terreus[1].

  • CAS Number: 70407-19-1
  • MF: C28H30O9
  • MW: 510.53200
  • Catalog: Others
  • Density: 1.44g/cm3
  • Boiling Point: 695ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 232ºC

Bonemarrow-Derived Mesenchymal Stem Cells Affinity Peptide trifluoroacetate salt

H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OH (EM7) is a mesenchymal stem cells (MSC)-specific peptide[1].

  • CAS Number: 683750-83-6
  • MF: C38H67N9O11S
  • MW: 858.06
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tetrahydropapaverine hydrochloride

Tetrahydropapaverine hydrochloride is one of the Tetrahydroisoquinolines. Tetrahydropapaverine hydrochloride has neurotoxic effects on dopamine neurons[1][2].

  • CAS Number: 6429-04-5
  • MF: C20H26ClNO4
  • MW: 379.878
  • Catalog: Neurological Disease
  • Density: 1.12g/cm3
  • Boiling Point: 475.8ºC at 760 mmHg
  • Melting Point: 213-215ºC
  • Flash Point: 202.7ºC

Dihydrofuran-3(2H)-one

Dihydrofuran-3(2H)-one (3-Oxotetrahydrofuran) is used for synthesizing cyclic ketone inhibitors that inhibits the serine protease plasmin[1].

  • CAS Number: 22929-52-8
  • MF: C4H6O2
  • MW: 86.089
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 151.1±23.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 56.3±16.2 °C

Fmoc-D-Lys(Z)-OH

N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-((benzyloxy)carbonyl)-D-lysine is a lysine derivative[1].

  • CAS Number: 110990-07-3
  • MF: C29H30N2O6
  • MW: 502.55800
  • Catalog: Others
  • Density: 1.261 g/cm3
  • Boiling Point: 751.2ºC at 760 mmHg
  • Melting Point: 106-110℃
  • Flash Point: N/A

Ethyl cellulose

Ethyl cellulose is a derivative of cellulose. Ethyl cellulose serves as a non-toxic and biodegradable polymer, with unique properties such as oleogel formation, delivery of active component, and film-forming ability in the food and pharmaceutical sectors. Ethyl cellulose can be used as an excipient, such as coating agent, flavoring agent, tablet filler. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

  • CAS Number: 9004-57-3
  • MF: C23H24N6O4
  • MW: 448.474
  • Catalog: Others
  • Density: 1.45
  • Boiling Point: 654.2±55.0 °C at 760 mmHg
  • Melting Point: 240-255ºC
  • Flash Point: 349.5±31.5 °C

Perillartine

Perillartine is a sweetener, which activates the taste receptor type 1 member 2 (Tas1r2) subunit in a species-dependent manner.

  • CAS Number: 30950-27-7
  • MF: C10H15NO
  • MW: 165.232
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 271.4±40.0 °C at 760 mmHg
  • Melting Point: 102°C
  • Flash Point: 158.3±16.6 °C

STX64

Irosustat is a potent steroid sulfatase inhibitor, with an IC50 of 8 nM, and exhibits anti-breast cancer activity.

  • CAS Number: 288628-05-7
  • MF: C14H15NO5S
  • MW: 309.33800
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-Hydroxyaristolochic acid A

7-Hydroxyaristolochic acid A is an aristolochic acid analogue found in Aristolochia plants. Aristolochic acid can be used as an anti-inflammatory agent[1].

  • CAS Number: 79185-75-4
  • MF: C17H11NO8
  • MW: 357.271
  • Catalog: Inflammation/Immunology
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 663.7±55.0 °C at 760 mmHg
  • Melting Point: 287-292°C
  • Flash Point: 355.2±31.5 °C

8-Deacetylyunaconitine

8-Deacetylyunaconitine, a diterpenoid alkaloid, can be found in the root extract of A. forrestii[1].

  • CAS Number: 93460-55-0
  • MF: C33H47NO10
  • MW: 617.727
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-D-Leu-Tyr-OH

(S)-2-((R)-2-Amino-4-methylpentanamido)-3-(4-hydroxyphenyl)propanoic acid hydrate is a tyrosine derivative[1].

  • CAS Number: 3303-29-5
  • MF: C15H22N2O4
  • MW: 294.34600
  • Catalog: Others
  • Density: 1.218 g/cm3
  • Boiling Point: 560ºC at 760 mmHg
  • Melting Point: 260 °C
  • Flash Point: 292.5ºC

Biotinyl-Neuropeptide W-23 (human) trifluoroacetate salt

Biotinyl-neuropeptide W-23 (human) is a biotinylated neuropeptide W-23 (human) (HY-P1035). Neuropeptide W-23 (human) is an agonist of NPBW1 (GPR7) and NPBW2 (GPR8)[1][2].

  • CAS Number: 1815618-09-7
  • MF: C129H197N37O30S2
  • MW: 2810.304
  • Catalog: Neurological Disease
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,5,8-Trihydroxy-3-methoxy-2-prenylxanthone

1,5,8-Trihydroxy-3-methoxy-2-prenylxanthone is a natural product that can be isolated from the herbs of Garcinia mangostana[1].

  • CAS Number: 110187-11-6
  • MF: C19H18O6
  • MW: 342.343
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 591.8±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 216.0±23.6 °C

H-Gly-Gly-NH2

Glycylglycinamide is a biologically active peptide.

  • CAS Number: 20238-94-2
  • MF: C4H9N3O2
  • MW: 131.13300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-Acetylsalicylic acid

5-Acetylsalicylic acid has anti-inflammatory and is considered to be the active agent in inflammatory bowel disease (IBD)[1].

  • CAS Number: 13110-96-8
  • MF: C9H8O4
  • MW: 180.15700
  • Catalog: Inflammation/Immunology
  • Density: 1.365 g/cm3
  • Boiling Point: 413ºC at 760 mmHg
  • Melting Point: 214-216°C
  • Flash Point: 250°C

Senkyunolide C

Senkyunolide C is a natural product, that can be isolated from the rhizome of Cnidium officinale[1].

  • CAS Number: 91652-78-7
  • MF: C12H12O3
  • MW: 204.22
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 387.1±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 171.7±20.7 °C

Nordefrin

Nordefrin ((±)-Cobefri), a Norepinephrine derivative, is a vasoconstrictor agent[1].

  • CAS Number: 74812-63-8
  • MF: C9H13NO3
  • MW: 183.20
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-(Phenylazo)-2,6-pyridinediamine

Phenazopyridine has a local analgesic effect on the urinary tract, often used to alleviate the pain, irritation, discomfort, or urgency caused by urinary tract infections, surgery, or injury to the urinary tract[1].

  • CAS Number: 94-78-0
  • MF: C11H11N5
  • MW: 213.23900
  • Catalog: Others
  • Density: 1.32g/cm3
  • Boiling Point: 442.3ºC at 760mmHg
  • Melting Point: 235 - 240ºC
  • Flash Point: N/A

Isoagarotetrol

Isoagarotetrol is a natural product isolated from agalwood[1].

  • CAS Number: 104060-61-9
  • MF: C17H18O6
  • MW: 318.32100
  • Catalog: Others
  • Density: 1.48±0.1 g/cm3(Predicted)
  • Boiling Point: 581.3±50.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

Elliotinol

trans-Communol is a labdane diterpenoid, can be isolated from the aerial parts of Salvia cinnabarina[1].

  • CAS Number: 10178-31-1
  • MF: C20H32O
  • MW: 288.467
  • Catalog: Others
  • Density: 1.0±0.0 g/cm3
  • Boiling Point: 380.4±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 126.6±0.0 °C

Exoticin

Exoticin is a natural product that can be isolated from the leaves of Nicotiana plumbaginifolia[1].

  • CAS Number: 13364-94-8
  • MF: C23H26O10
  • MW: 462.447
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 641.5±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 275.9±31.5 °C

LRH-1 modulator-1

LRH-1 modulator-1 (compound 6N) is a potent LRH-1 (liver receptor homolog-1) modulator/agonist. LRH-1 modulator-1 shows anti-inflammatory effects in intestinal organoids. LRH-1 modulator-1 induces anti-inflammatory cytokine IL-10, and reduces inflammatory cytokine IL-1b and TNFa[1].

  • CAS Number: 2244781-29-9
  • MF: C28H36N2O2S
  • MW: 464.66
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sodium Aescinate

Sodium aescinate is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities[1]. Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway[2].

  • CAS Number: 20977-05-3
  • MF: C54H83NaO23
  • MW: 1124.2202
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Alacizumab pegol

Alacizumab pegol (CDP-791) is a pegylated antibody fragment directed against KDR. Alacizumab pegol can be used for the research of cancer[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A