SOD1-Derlin-1 inhibitor-1

Modify Date: 2025-08-25 20:27:55

SOD1-Derlin-1 inhibitor-1 Structure
SOD1-Derlin-1 inhibitor-1 structure
 Common Name SOD1-Derlin-1 inhibitor-1
CAS Number 840461-03-2 Molecular Weight 504.20
Density N/A Boiling Point N/A
Molecular Formula C19H12Br2N4OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SOD1-Derlin-1 inhibitor-1


SOD1-Derlin-1 inhibitor-1 (compound 56-20) is an inhibitor of SOD1-Derlin-1 interaction. SOD1-Derlin-1 inhibitor-1 inhibits SOD1G93A-Derlin-1 complex with an IC50 value of 7.11 μM. SOD1-Derlin-1 inhibitor-1 can be used for the research of amyotrophic lateral sclerosis[1].

 Names

Name SOD1-Derlin-1 inhibitor-1

 SOD1-Derlin-1 inhibitor-1 Biological Activity

Description SOD1-Derlin-1 inhibitor-1 (compound 56-20) is an inhibitor of SOD1-Derlin-1 interaction. SOD1-Derlin-1 inhibitor-1 inhibits SOD1G93A-Derlin-1 complex with an IC50 value of 7.11 μM. SOD1-Derlin-1 inhibitor-1 can be used for the research of amyotrophic lateral sclerosis[1].
Related Catalog
Target

IC50: 7.11 μM (SOD1G93A-Derlin-1 complex)[1]

In Vitro SOD1-Derlin-1 inhibitor-1 (50 μM; 16 h) inhibits SOD1G93A-Derlin-1 complex with an IC50 value of 7.11 μM[1]. SOD1-Derlin-1 inhibitor-1 (250 nM; 6 h) interacts with SOD1G93A with a Kd value of 81.1 μM[1].
References

[1]. Tsuburaya N, et al. A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model. Nat Commun. 2018 Jul 10;9(1):2668.

 Chemical & Physical Properties

Molecular Formula C19H12Br2N4OS
Molecular Weight 504.20
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Chemsrc provides SOD1-Derlin-1 inhibitor-1(CAS#:840461-03-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of SOD1-Derlin-1 inhibitor-1 are included as well.>> amp version: SOD1-Derlin-1 inhibitor-1

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