2170170-27-9
2170170-27-9 structure
- Name: SOD1-Derlin-1 inhibitor 56-59
- Chemical Name: SOD1-Derlin-1 inhibitor 56-59
- CAS Number: 2170170-27-9
- Molecular Formula: C22H18N4OS
- Molecular Weight: 386.473
- Catalog: Research Areas Neurological Disease
- Create Date: 2020-01-11 16:16:53
- Modify Date: 2024-01-22 08:59:51
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SOD1-Derlin-1 inhibitor 56-59 is a cell-permeable, small molecule inhibitor of SOD1-Derlin-1 interaction, target SOD1 DBR and clearly attenuates the interactions of Derlin-1 with 122 types of SOD1mut in the cell-based co-immunoprecipitation assay; significantly ameliorates the ALS pathology both in motoneurons derived from patient induced pluripotent stem cells and in model mice.
| Name | SOD1-Derlin-1 inhibitor 56-59 |
|---|
| Description | SOD1-Derlin-1 inhibitor 56-59 is a cell-permeable, small molecule inhibitor of SOD1-Derlin-1 interaction, target SOD1 DBR and clearly attenuates the interactions of Derlin-1 with 122 types of SOD1mut in the cell-based co-immunoprecipitation assay; significantly ameliorates the ALS pathology both in motoneurons derived from patient induced pluripotent stem cells and in model mice. |
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| References | References 1. Tsuburaya N, et al. Nat Commun. 2018 Jul 10;9(1):2668. View Related Products by Target Other Targets |
| Molecular Formula | C22H18N4OS |
|---|---|
| Molecular Weight | 386.473 |
| Storage condition | -20°C |