27856-54-8
27856-54-8 structure
- Name: Lamiide
- Chemical Name: lamiide
- CAS Number: 27856-54-8
- Molecular Formula: C17H26O12
- Molecular Weight: 422.381
- Catalog: Natural product Iridoid derivative
- Create Date: 2018-04-23 08:00:00
- Modify Date: 2024-01-10 17:15:24
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Lamiide, an orally active iridoid compound, can be found in Bouchea fluminensis leaves. Lamiide exhibits anti-inflammatory and anti-lipoperoxidative activity[1].
| Name | lamiide |
|---|---|
| Synonyms |
Methyl (1S,4aR,6S,7R,7aS)-1-(β-D-glucopyranosyloxy)-4a,6,7-trihydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate
Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-4a,6,7-trihydroxy-7-methyl-, methyl ester, (1S,4aR,6S,7R,7aS)- |
| Description | Lamiide, an orally active iridoid compound, can be found in Bouchea fluminensis leaves. Lamiide exhibits anti-inflammatory and anti-lipoperoxidative activity[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Lamiide inhibits rat-brain phospholipid peroxidation, with an IC50 of 0.92 mM[1]. |
| In Vivo | Lamiide (12.5-100 mg/kg; p.o. 30 min before Carrageenin injection) dose-dependently reduces Carrageenin-induced edema[1]. Animal Model: Female Wistar rats (8-weeks old, 150-200 g) were injected with Carrageenin in the subplantar aponeurosis of the right hind paw[1] Dosage: 12.5, 25, 50, 100 mg/kg Administration: P.o. 30 min before Carrageenin injection Result: Reduced Carrageenin-induced edema, with an ED50 of 62.3 mg/kg. |
| References |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 667.2±55.0 °C at 760 mmHg |
| Molecular Formula | C17H26O12 |
| Molecular Weight | 422.381 |
| Flash Point | 237.8±25.0 °C |
| Exact Mass | 422.142426 |
| PSA | 195.60000 |
| LogP | -3.03 |
| Vapour Pressure | 0.0±4.6 mmHg at 25°C |
| Index of Refraction | 1.644 |
| Storage condition | ?20°C |
| RIDADR | NONH for all modes of transport |
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