Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

H-Thr-Pro-Asn-Gln-Arg-Gln-Asn-Val-Cys-OH trifluoroacetate salt

TPNQRQNVC is a nonapeptide and is the epitope of HLA-B0702. TPNQRQNVC induces a CD8+ T cell immune response[1].

  • CAS Number: 2022956-41-6
  • MF: C41H70N16O15S
  • MW: 1059.17
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N2-(tert-Butyl)-N4-cyclopropyl-6-(methylthio)-1,3,5-triazine-2,4-diamine-d9

N2-(tert-Butyl)-N4-cyclopropyl-6-(methylthio)-1,3,5-triazine-2,4-diamine-d9 is the deuterium labeled N2-(tert-Butyl)-N4-cyclopropyl-6-(methylthio)-1,3,5-triazine-2,4-diamine[1].

  • CAS Number: 1189926-01-9
  • MF: C11H19N5S
  • MW: 253.367
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 347.2±25.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 163.8±23.2 °C

17:0-22:4 PE-d5

17:0-22:4 PE-d5 is deuterium labeled 17:0-22:4 PE.

  • CAS Number: 2342575-44-2
  • MF: C44H75D5NO8P
  • MW: 787.11
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isoginsenoside Rh3

Isoginsenoside-Rh3 is a triterpenoid saponin from the fruits of Panax ginseng C. A. Mey[1].

  • CAS Number: 166040-90-0
  • MF: C36H60O7
  • MW: 604.85700
  • Catalog: Others
  • Density: 1.17±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

EZH2-IN-11

EZH2-IN-11 is a potent inhibitor of E2HZ. The oncogenic activities of EZH2 have been shown by a number of studies in various different cancer types. EZH2-IN-11 has the potential for the research of cancer diseases (extracted from patent WO2019204490A1, compound 17)[1].

  • CAS Number: 2387402-80-2
  • MF: C28H36ClN3O5S
  • MW: 562.12
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-D-Valine

tert-Butoxycarbonyl-D-valine is a valine derivative[1].

  • CAS Number: 22838-58-0
  • MF: C10H19NO4
  • MW: 217.262
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 341.8±25.0 °C at 760 mmHg
  • Melting Point: 164-165ºC
  • Flash Point: 160.5±23.2 °C

Fursultiamine

Fursultiamine is a vitamin B1 derivative.

  • CAS Number: 804-30-8
  • MF: C17H26N4O3S2
  • MW: 398.543
  • Catalog: Inflammation/Immunology
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 652.3±55.0 °C at 760 mmHg
  • Melting Point: 130-136ºC (decompos.)
  • Flash Point: 348.3±31.5 °C

D-Galactosyl-β-1,1'-N-tridecanoyl-D-erythro-sphingosine-d7

D-Galactosyl-β-1,1'-N-tridecanoyl-D-erythro-sphingosine-d7 is deuterium labeled D-Galactosyl-β-1,1'-N-tridecanoyl-D-erythro-sphingosine.

  • CAS Number: 2315262-19-0
  • MF: C37H64D7NO8
  • MW: 665.00
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Phenylhexane-d5

1-Phenylhexane-d5 is the deuterium labeled 1-Phenylhexane[1].

  • CAS Number: 1219799-07-1
  • MF: C12H18
  • MW: 162.271
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 226.0±3.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 83.3±0.0 °C

Spathulenol

Spathulenol is isolated from Psidium guineense Sw, and has antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities. Spathulenol shows a high antioxidant activity with an IC50 of 85.60 μg/mL in the DPPH system[1].

  • CAS Number: 6750-60-3
  • MF: C15H24O
  • MW: 220.350
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 297.0±19.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 123.9±13.7 °C

BR102910

BR102910 is a selective fibroblast activation protein (FAP) inhibitor with the IC50 of 2 nM. BR102910 also inhibits prolyl oligopeptidase (PREP) with the IC50 of 49.00 μM. BR102910 can be used for the researchof type 2

  • CAS Number: 2505339-54-6
  • MF: C18H14Cl2F2N4O2S
  • MW: 459.30
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DO34

DO34 is a highly potent, selective and centrally active diacylglycerol lipase (DAGL) inhibitor, with an IC50 of 6 nM for DAGLα conversion of SAG to 2-AG, and an IC50 for DAGLβ.

  • CAS Number: 1848233-58-8
  • MF: C26H28F3N5O4
  • MW: 531.53
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Promestriene-d3

Promestriene-d3 is the deuterium labeled Promestriene. Promestriene is a synthetic diethyl-ether of estradiol and a locally effective estrogen. Promestriene has an efficient action on vaginal atrophy while it is minimally absorbed[1][2].

  • CAS Number: 1316849-37-2
  • MF: C22H29D3O2
  • MW: 331.51
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bernardioside A

Bernardioside A is a triterpenoid saponin isolated from Bellis bernardii[1][2].

  • CAS Number: 121368-52-3
  • MF: C36H58O11
  • MW: 666.839
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 817.0±65.0 °C at 760 mmHg
  • Melting Point: 233 °C
  • Flash Point: 249.7±27.8 °C

[Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2

[Arg-15,-20,-21,Leu17]-PACAP-Gly-Lys-Arg-NH2 (BM-PACAP) is a synthetic PACAP 1-27 (HY-P0176) analogue with relaxant effect[1].

  • CAS Number: 176785-25-4
  • MF: C157H253N53O42
  • MW: 3555.02
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BM152054

BM152054 can promote glucose utilization in peripheral tissues by enhancing insulin action.

  • CAS Number: 213411-84-8
  • MF: C22H18N2O4S3
  • MW: 470.58
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Docosyl (2E)-3-(3,4-dihydroxyphenyl)acrylate

(E)-Docosyl caffeate (compound 1) can be isolated from the halophytic plant Halocnemum strobilaceum[1].

  • CAS Number: 28593-92-2
  • MF: C31H52O4
  • MW: 488.74
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 604.0±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 182.5±22.2 °C

Trioxsalen

Trioxsalen is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death.

  • CAS Number: 3902-71-4
  • MF: C14H12O3
  • MW: 228.243
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 389.0±30.0 °C at 760 mmHg
  • Melting Point: 229-231ºC(lit.)
  • Flash Point: 189.1±24.6 °C

2-(4-BIPHENYLYL)-5-PHENYL-1,3,4-OXADIAZOLE

2-(4-Biphenylyl)-5-phenyl-1,3,4-oxadiazole is a laser dyes with high photoluminescence (PL) quantum efficiency[1].

  • CAS Number: 852-38-0
  • MF: C20H14N2O
  • MW: 298.33800
  • Catalog: Others
  • Density: 1.172g/cm3
  • Boiling Point: 480.7ºC at 760 mmHg
  • Melting Point: 167-169 °C(lit.)
  • Flash Point: 240.7ºC

4-(3,5-DIBROMO-2-PYRIDYLAZO)-N-ETHYL-N-(3-SULFOPROPYL)ANILINE, MONOSODIUM SALT, MONOHYDRATE

3,5-DiBr-PAESA is a supersensitive chelating agent that can be used for silver (I) determination in water in the case of absence of other interfering ions. 3,5-DiBr-PAESA can also be used for copper (II) determination[1].

  • CAS Number: 100743-65-5
  • MF: C16H19Br2N4NaO4S
  • MW: 546.20900
  • Catalog: Others
  • Density: 1.69g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Condurango glycoside E

Condurango glycoside E is a glycoside compound that can be isolated from the bark extract of Marsdenia cundurango[1].

  • CAS Number: 115784-07-1
  • MF: C53H76O18
  • MW: 1001.17
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(1beta,3beta,25S)-3-Hydroxyspirost-5-en-1-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-xylopyranoside

25(S)-Ruscogenin-1-O-α-L-rhamnopyranosyl (1→2)-β-D-xylopyranoside shows inhibitory activity of neutrophil respiratory burst stimulated by PMA(phorbol myristate acetate)[1].

  • CAS Number: 125225-63-0
  • MF: C38H60O12
  • MW: 708.88
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Acacetin 7-O-β-D-xylopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside

Acacetin 7-O-β-D-xylopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside (Compound 10), a flavone glycoside, can be isolated from extracts of the leaves of Robinia pseudoacacia[1].

  • CAS Number: 64191-68-0
  • MF: C33H40O18
  • MW:
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-Hydroxyflavone

5-Hydroxyflavone, a flavonoid ligand, shows no cytotoxic activity against MCF-7, FaDU, MDA-MB-435S, U87, RPE-1, and HEK293 cells[1].

  • CAS Number: 491-78-1
  • MF: C15H10O3
  • MW: 238.23800
  • Catalog: Others
  • Density: 1.34g/cm3
  • Boiling Point: 425ºC at 760 mmHg
  • Melting Point: 158-160°C
  • Flash Point: 165.4ºC

Endotrophin (mouse) trifluoroacetate salt

Endotrophin (Mus musculus) is a cleavage product of collagen 6 (Col6). Endotrophin upregulation of both profibrotic and proinflammatory genes[1].

  • CAS Number: 1678414-54-4
  • MF:
  • MW:
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

acitazanolast

Acitazanolast is an orally active antiallergic agent, can inhibit histamine release. Acitazanolast can be used in study of type I anaphylaxis (immediate) caused by IgE antibodies[1].

  • CAS Number: 114607-46-4
  • MF: C9H7N5O3
  • MW: 233.184
  • Catalog: Inflammation/Immunology
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tyrosinase-IN-5

Tyrosinase-IN-5 (compound 16c) is a potent inhibitor of tyrosinase with an IC50 of 0.02 μM. Tyrosinase-IN-5 efficiently suppresses the melanogenesis without significant toxicity on cells[1].

  • CAS Number: 2525175-90-8
  • MF: C18H13N3O6
  • MW: 367.31
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-PHG-OMEHCL

(S)-(+)-2-Phenylglycine methyl ester hydrochloride is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 15028-39-4
  • MF: C9H12ClNO2
  • MW: 201.650
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 238.9ºC at 760mmHg
  • Melting Point: 200ºC (dec.)(lit.)
  • Flash Point: 104.7ºC

1,2-Diamino-4,5-dimethoxybenzene

4,5-Dimethoxybenzene-1,2-diamine 4,5-Dimethoxybenzene-1,2-diamine can be used as a standard for the determination of methyldiacetaldehyde, an intermediate product of glycolysis and a diabetic ketone Biomarkers of acidosis[1].

  • CAS Number: 27841-33-4
  • MF: C8H12N2O2
  • MW: 168.19
  • Catalog: Metabolic Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 329.0±37.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 174.8±20.2 °C

odoratone

Odoratone (Dehydroodoratol) has insecticidal activity (LC50: 154 ppm)[1].

  • CAS Number: 16962-90-6
  • MF: C30H48O4
  • MW: 472.700
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 571.2±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 177.5±23.6 °C