Tyrphostin AG 30 structure
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Common Name | Tyrphostin AG 30 | ||
|---|---|---|---|---|
| CAS Number | 122520-79-0 | Molecular Weight | 205.16700 | |
| Density | 1.559g/cm3 | Boiling Point | 465.6ºC at 760mmHg | |
| Molecular Formula | C10H7NO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 235.4ºC | |
Use of Tyrphostin AG 30Tyrphostin AG30 (AG30) is a potent protein tyrosine kinases (PTK) inhibitor. Tyrphostin AG30 (AG30) selectively inhibits self renewal induction by c-ErbB, and is able to inhibit activation of STAT5 by c-ErbB in primary erythroblasts[1][2]. |
| Name | (E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Tyrphostin AG30 (AG30) is a potent protein tyrosine kinases (PTK) inhibitor. Tyrphostin AG30 (AG30) selectively inhibits self renewal induction by c-ErbB, and is able to inhibit activation of STAT5 by c-ErbB in primary erythroblasts[1][2]. |
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| Related Catalog | |
| References |
| Density | 1.559g/cm3 |
|---|---|
| Boiling Point | 465.6ºC at 760mmHg |
| Molecular Formula | C10H7NO4 |
| Molecular Weight | 205.16700 |
| Flash Point | 235.4ºC |
| Exact Mass | 205.03800 |
| PSA | 101.55000 |
| LogP | 1.08938 |
| Vapour Pressure | 1.8E-09mmHg at 25°C |
| Index of Refraction | 1.717 |
| Hazard Codes | Xi |
|---|
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~68%
Tyrphostin AG 30 CAS#:122520-79-0 |
| Literature: Journal of Pharmaceutical Sciences, , vol. 80, # 5 p. 416 - 418 |
|
~%
Tyrphostin AG 30 CAS#:122520-79-0 |
| Literature: Journal of Medicinal Chemistry, , vol. 32, # 10 p. 2344 - 2352 |
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~%
Tyrphostin AG 30 CAS#:122520-79-0 |
| Literature: Journal of Medicinal Chemistry, , vol. 34, # 4 p. 1503 - 1505 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |
| 3.4-Dioxy-benzylidencyanessigsaeure |
| 2-cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid |
| (E)-2-cyano-3-(3,4-dihydroxyphenyl)acrylic acid |
| AG 30 |
| 2-Propenoic acid,2-cyano-3-(3,4-dihydroxyphenyl)-,(E) |
| Tyrphostin AG 30 |
| (E)-2-Cyano-3-(3,4-dihydroxyphenyl)-2-propenoic acid |
| Tyrophostin AG 30 |
| 2-Cyan-3-(3,4-dihydroxy-phenyl)-acrylsaeure |