133550-49-9
133550-49-9 structure
- Name: Tyrphostin AG 528
- Chemical Name: Tyrphostin AG 528
- CAS Number: 133550-49-9
- Molecular Formula: C18H14N2O3
- Molecular Weight: 306.31500
- Catalog: Research Areas Cancer
- Create Date: 2018-01-08 00:12:34
- Modify Date: 2025-09-02 18:00:30
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Tyrphostin AG 528 is an inhibitor of EGFR and ErbB2 with IC50s of 4.9 and 2.1 μM, respectively.
| Name | Tyrphostin AG 528 |
|---|---|
| Synonyms |
N-(3',4'-dihydroxybenzylidenecyanoacetyl)indoline
(E)-2-(2,3-Dihydro-indole-1-carbonyl)-3-(3,4-dihydroxy-phenyl)-acrylonitrile |
| Description | Tyrphostin AG 528 is an inhibitor of EGFR and ErbB2 with IC50s of 4.9 and 2.1 μM, respectively. |
|---|---|
| Related Catalog | |
| Target |
EGFR:4.9 μM (IC50) ErbB2:2.1 μM (IC50) |
| References |
| Melting Point | 215 °C |
|---|---|
| Molecular Formula | C18H14N2O3 |
| Molecular Weight | 306.31500 |
| Exact Mass | 306.10000 |
| PSA | 84.56000 |
| LogP | 2.65908 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |