Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

FR901464

FR901464 is a potent spliceosome inhibitor with prominent anti-tumor and anti-cancer effects[1].

  • CAS Number: 146478-72-0
  • MF: C27H41NO8
  • MW: 507.61600
  • Catalog: Cancer
  • Density: 1.21g/cm3
  • Boiling Point: 702.7ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 378.8ºC

Homobaldrinal

Homobaldrinal is a decomposition product of Valepotriate (HY-N0718). Homobaldrinal exhibits genotoxic activity in the Salmonella/microsome test[1].

  • CAS Number: 67910-07-0
  • MF: C15H16O4
  • MW: 260.285
  • Catalog: Neurological Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 462.1±30.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 207.4±24.6 °C

(R)-3-phenyl-2-(pyrazine-2-carboxamido)propanoic acid

N-(2-Pyrazinylcarbonyl)-D-phenylalanine is a phenylalanine derivative[1].

  • CAS Number: 1608986-16-8
  • MF: C14H13N3O3
  • MW: 271.271
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 573.8±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 300.8±30.1 °C

Goniodiol 8-acetate

Goniodiol 8-acetate is a styrylpyrones that can be isolated from the leaves of Goniothalamus amuyon. Goniodiol 8-acetate has cytotoxic activity[1].

  • CAS Number: 144429-71-0
  • MF: C15H16O5
  • MW: 276.284
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 412.4±15.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 151.5±13.9 °C

2-(4-(Sec-butoxy)-3-cyanophenyl)-4-methylthiazole-5-carboxylic acid

Febuxostat sec-butoxy acid is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1].

  • CAS Number: 1335202-59-9
  • MF: C16H16N2O3S
  • MW: 316.37
  • Catalog: Others
  • Density: 1.31±0.1 g/cm3 (20 ºC 760 Torr)
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methyl 5-hydroxypyridine-2-carboxylate

Methyl 5-hydroxypyridine-2-carboxylate is a phenolic acid that can found in the stems of Mahonia fortune. Methyl 5-hydroxypyridine-2-carboxylate exhibits NO inhibitory effects in vitro[1].

  • CAS Number: 30766-12-2
  • MF: C7H7NO3
  • MW: 153.135
  • Catalog: Inflammation/Immunology
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 374.2±22.0 °C at 760 mmHg
  • Melting Point: 193.5-195.5℃
  • Flash Point: 180.1±22.3 °C

1,2-DIAMINOANTHRAQUINONE

1,2-Diaminoanthraquinone is a sensitivity, specificity and nontoxic nitric oxide (NO) fluorescent probe. 1,2-Diaminoanthraquinone can be used to detect NO productions in live cell and animals with a maximum of absorption at about 540 nm and a detection limit of 5 μM for NO[1][2].

  • CAS Number: 1758-68-5
  • MF: C14H10N2O2
  • MW: 238.24100
  • Catalog: Others
  • Density: 1.456 g/cm3
  • Boiling Point: 548.8ºC at 760 mmHg
  • Melting Point: 289-291 °C(lit.)
  • Flash Point: 285.7ºC

Flavin adenine dinucleotide disodium salt

Flavin Adenine Dinucleotide Disodium is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

  • CAS Number: 84366-81-4
  • MF: C27H31N9Na2O15P2
  • MW: 829.51
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Nodakenetin

Nodakenetin, isolated from Angelica decursiva, possesses antioxidant anti-inflammatory activities. Nodakenetin has the potential to be an antiarthritic and nerve tonic[1][2].

  • CAS Number: 495-32-9
  • MF: C14H14O4
  • MW: 246.259
  • Catalog: Inflammation/Immunology
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 434.0±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 168.0±22.2 °C

(Rac)-Methylindazone

(Rac)-Methylindazone ((Rac)-IAA-94) is the racemate of Methylindazone. Methylindazone is a potent CLIC1 channel blocker[1].

  • CAS Number: 53108-00-2
  • MF: C17H18Cl2O4
  • MW: 357.23
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

T01-1

T01-1 is an anticancer agent (camptothecin derivative) with good anti-proliferative activity[1].

  • CAS Number: 2356229-14-4
  • MF: C26H29N3O6S
  • MW: 511.59
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

tert-butyl 4-oxopiperidine-1-carboxylate-3,3,5,5-d4

tert-Butyl 4-oxopiperidine-1-carboxylate-3,3,5,5-d4 is the deuterium labeled tert-Butyl 4-oxopiperidine-1-carboxylate[1].

  • CAS Number: 1246342-66-4
  • MF: C10H13D4NO3
  • MW: 203.271527112
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bidenoside C

Bidenoside C (compound 10) is a polyacetylene glycoside (Polyacetylene Glycoside), which can be isolated from the flowers of Coreopsis lanceolata (Asteraceae)[1].

  • CAS Number: 700877-55-0
  • MF: C16H22O6
  • MW: 310.35
  • Catalog: Others
  • Density: 1.30±0.1 g/cm3(Predicted)
  • Boiling Point: 546.3±50.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

Didrovaltrate

Didrovaltrate (Didrovaltratum), isolated from the roots of Valeriana wallichii D.C, is a cytotoxic and antitumor agent[1].

  • CAS Number: 18296-45-2
  • MF: C22H32O8
  • MW: 424.485
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 507.5±50.0 °C at 760 mmHg
  • Melting Point: 63-64℃
  • Flash Point: 217.7±30.2 °C

N-(2-NITROPHENYLSULFENYL)-L-ASPARAGINE (DICYCLOHEXYLAMMONIUM) SALT

N-(2-Nitrophenylsulfenyl)-L-asparagine (dicyclohexylammonium) salt is an asparagine derivative[1].

  • CAS Number: 7675-59-4
  • MF: C22H34N4O5S
  • MW: 466.59400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Crystal Violet

Crystal violet is a triarylmethane dye.Target: OthersCrystal Violet is a component of Gram staining that allows one to recognize the difference between gram-positive and gram-negative bacteria with differential staining. The compound helps to access bacterial contamination of tissue culture samples. The staining response is due to the difference in the chemical and structural composition of the cell walls in different bacteria. Crystal Violet can also be used to test the different species of archaea and the cytostatic/cytotoxic effects on tumor cell lines [1-3].

  • CAS Number: 548-62-9
  • MF: C25H30ClN3
  • MW: 407.979
  • Catalog: Dye Reagents
  • Density: 1.19 g/cm3 (20ºC)
  • Boiling Point: N/A
  • Melting Point: 215ºC
  • Flash Point: 40ºC

Drinidene

Drinidene can be used for the research of pain disorders extracted from patent AU2018254530A1[1].

  • CAS Number: 53394-92-6
  • MF: C10H9NO
  • MW: 159.18500
  • Catalog: Neurological Disease
  • Density: 1.333g/cm3
  • Boiling Point: 306.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 138.9ºC

Bkm1644

BKM1644 is an effective inhibition of the proliferation of metastatic, castration-resistant PCa (mCRPC) cells.

  • CAS Number: 1070966-96-9
  • MF: C34H37Cl2F5N2O9P2
  • MW: 845.51
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isoxanthohumol

(2S)-Isoxanthohumol is a microbial biotransformed metabolite of the hop prenylflavanone Isoxanthohumol[1].

  • CAS Number: 70872-29-6
  • MF: C21H22O5
  • MW: 354.396
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 585.8±50.0 °C at 760 mmHg
  • Melting Point: 196-208℃
  • Flash Point: 208.6±23.6 °C

PCI-32765 (Racemate)

Ibrutinib Racemate (PCI-32765 Racemate) is the racemate of Ibrutinib. Ibrutinib is a selective, irreversible Btk inhibitor with IC50 value of 0.5 nM.

  • CAS Number: 936563-87-0
  • MF: C25H24N6O2
  • MW: 440.49700
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BIS(2-CYANOETHYL) DIISOPROPYLPHOSPHORAMIDITE

Bis(2-cyanoethyl) diisopropylphosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides[1].

  • CAS Number: 102690-88-0
  • MF: C12H22N3O2P
  • MW: 271.30
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 335.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 156.6ºC

β-Gentiobiose

β-Gentiobiose (Gentiobiose) is a naturally occurring oligosaccharin with a rapid turnover rate in ripening tomato fruit[1].

  • CAS Number: 554-91-6
  • MF: C12H22O11
  • MW: 342.29600
  • Catalog: Others
  • Density: 1.76 g/cm3
  • Boiling Point: 662.8ºC at 760 mmHg
  • Melting Point: 195-197 °C (dec.)
  • Flash Point: 354.6ºC

Justin C

Justin C (compound 14) is a nature product that could be isolated from Justicia procumbens. Justin C can be used in research of cancer[1].

  • CAS Number: 202655-28-5
  • MF: C26H34O9
  • MW: 490.54
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

meso-Tetra (p-bromophenyl) porphine

Tetra(p-bromophenyl)porphyrin (compound 5c) is a fluorescent dye. Tetra(p-bromophenyl)porphyrin can be used for the synthesis of perfuoroalkyl-substituted tetrakisphenylporphyrins[1].

  • CAS Number: 29162-73-0
  • MF: C44H26Br4N4
  • MW: 930.32
  • Catalog: Others
  • Density: 1.675g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d4

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d4 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glyc

  • CAS Number: 326495-35-6
  • MF: C44H84D4NO8P
  • MW: 794.17
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Monensin methyl ester

Monensin methyl ester, a neutral analog of monensin, is an ion active component for Na+ selective disk electrodes[1].

  • CAS Number: 28636-21-7
  • MF: C37H64O11
  • MW: 684.89700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-Cyano-7-deaza-2'-deoxy guanosine

7-Cyano-7-deaza-2'-deoxy guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

  • CAS Number: 199859-58-0
  • MF: C12H13N5O4
  • MW: 291.263
  • Catalog: Others
  • Density: 1.9±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BMP2-derived peptide

BMP2-derived peptide is a functional motif from positions 73 to 92 of the amino acid sequence of BMP-2. BMP2-derived peptide promotes osteogenic differentiation of bone marrow stromal cells (BMSCs) and enhances bone regeneration[1].

  • CAS Number: 836606-84-9
  • MF: C104H176N26O32S
  • MW: 2334.73
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Crassicauline A

Crassicauline A (Crassicaulin A) is a bioactive alkaloid found in roots of Aconitum carmichaeli. Crassicauline A (Crassicaulin A) possesses feeding deterrent activity against T. castaneum adults with an EC50 of 1134.5 ppm[1][2].

  • CAS Number: 79592-91-9
  • MF: C35H49NO10
  • MW: 643.764
  • Catalog: Neurological Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 688.2±55.0 °C at 760 mmHg
  • Melting Point: 166-168ºC
  • Flash Point: 370.0±31.5 °C

BODIPY 505/515

BODIPY 505/515, a lipophilic bright green fluorescent dye was tested for lipid detection in the microalga Tetraselmis subcordiformis. BODIPY 505/515 displays excitation/emission maxima of 505/515 nm, respectively, and has been used for live and fixed cell applications[1].

  • CAS Number: 21658-70-8
  • MF: C13H15BF2N2
  • MW: 248.08
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A