Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

pemirolast

Pemirolast is an orally active antiallergic agent. Pemirolast attenuates paclitaxel hypersensitivity reactions, can be used for bronchial asthma and conjunctivitis research[1]-[5].

  • CAS Number: 69372-19-6
  • MF: C10H8N6O
  • MW: 228.21000
  • Catalog: Inflammation/Immunology
  • Density: 1.64 g/cm3
  • Boiling Point: 454.8ºC at 760 mmHg
  • Melting Point: 310-311ºC (decomposes)
  • Flash Point: 228.9ºC

OICR-0547

OICR-0547 is a closely related derivative of OICR-9429. OICR-942 is a novel small-molecule antagonist of the Wdr5-MLL interaction, while OICR-0547 cannot bind to WDR5.

  • CAS Number: 1801873-49-3
  • MF: C28H29F3N4O4
  • MW: 542.55
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-(9-Acridinyl)-1H-pyrrole-2,5-dione

N-(9-Acridinyl)maleimide is a maleimide type fluorescent thiol reagent. N-(9-Acridinyl)maleimide shows no substantial fluorescence but its coupling products with thiol compounds exhibit strong blue fluorescence. N-(9-Acridinyl)maleimide is used for fluorometrical analysis of cysteine and glutathione[1].

  • CAS Number: 49759-20-8
  • MF: C17H10N2O2
  • MW: 274.273
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 508.2±23.0 °C at 760 mmHg
  • Melting Point: 188-190°C
  • Flash Point: 261.2±22.6 °C

Chlorthiamid

Chlorthiamid is a broad-spectrum herbicide. Chlorthiamid is an olfactory toxicant with a high in vivo covalent binding in the olfactory mucosa of mice[1].

  • CAS Number: 1918-13-4
  • MF: C7H5Cl2NS
  • MW: 206.09200
  • Catalog: Others
  • Density: 1.473g/cm3
  • Boiling Point: 320.6ºC at 760mmHg
  • Melting Point: 151-152°C
  • Flash Point: >100 °C

(2S)-2-Amino-4-pentynoic acid

(S)-2-Aminopent-4-ynoic acid is a synthetic amino acid. (S)-2-Aminopent-4-ynoic acid can be used in synthesis of folate-conjugates and corresponding metal-chelate complexes[1].

  • CAS Number: 23235-01-0
  • MF: C5H7NO2
  • MW: 113.115
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 272.1±35.0 °C at 760 mmHg
  • Melting Point: 232ºC
  • Flash Point: 118.3±25.9 °C

Dihydroalpinumisoflavone

Erythrivarone A is an isoflavone that can be isolated from the stem bark of Erythrina variegate[1].

  • CAS Number: 63807-90-9
  • MF: C20H18O5
  • MW: 338.35
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 555.8±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 202.2±23.6 °C

(1,1,2,3,3-pentadeuterio-2-hydroxy-3-octadecanoyloxypropyl) octadecanoate

1,3-18:0 DG-d5 is deuterium labeled 1,3-18:0 DG.

  • CAS Number: 1246523-69-2
  • MF: C39H71D5O5
  • MW: 630.04900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3'-​O-​Acetylhamaudol

3'-O-Acetylhamaudol, isolated from Angelica japonica roots, exhibits anti-tumor activity through dual actions, anti-angiogenesis and intestinal intraepithelial lymphocyte activation[1].

  • CAS Number: 30358-88-4
  • MF: C17H18O6
  • MW: 318.32
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methyl 3-(2,4-dihydroxyphenyl)propanoate

Methyl-3-(2,4-dihydroxy phenyl) propanoate is a phenylpropanoic ester with antifeedant activity[1].

  • CAS Number: 17422-90-1
  • MF: C10H12O4
  • MW: 196.200
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 348.7±11.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 138.3±12.8 °C

Cedrelopsin

Cedrelopsin is a natural phenylpropanoid compound[1].

  • CAS Number: 19397-28-5
  • MF: C15H16O4
  • MW: 260.285
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 457.6±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 172.7±22.2 °C

Visomitin

Visomitin is a new antioxidant with the highest mitochondrion membrane penetrating ability and potent antioxidant capability.

  • CAS Number: 934826-68-3
  • MF: C36H42BrO2P
  • MW: 617.595
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CART (61-102) (human, rat) trifluoroacetate salt

CART (61-102) (rat) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 209615-75-8
  • MF: C189H316N58O56S7
  • MW:
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(S)-Licoisoflavone A

(S)-Licoisoflavone A (Dihydrolicoisoflavone) is an isoflavanone that can be isolated from swartzia polyphylla[1].

  • CAS Number: 164163-92-2
  • MF: C20H20O6
  • MW: 356.37
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(5β,8α,10α)-Kaura-9(11),16-dien-18-oic acid

Grandiflorenic acid is a natural producr that can be found in Espeleth schultzii Wedd.[1].

  • CAS Number: 22338-67-6
  • MF: C20H28O2
  • MW: 300.44
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 447.5±44.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 209.7±23.1 °C

Heliotrine N-oxide

Heliotrine N-oxide is the corresponding PA (pyrrolizidine alkaloid) N-oxide of Heliotrine (HY-126128). Heliotrine N-oxide leads to the formation of pyrrolic DNA adducts and potential initiation of PA-induced liver tumors in vivo[1].

  • CAS Number: 6209-65-0
  • MF: C16H27NO6
  • MW: 329.38900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-(2-(dodecyloxy)ethoxy)ethanol

PEG 2 lauryl ether can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

  • CAS Number: 3055-93-4
  • MF: C16H34O3
  • MW: 274.44
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 371.1±17.0 °C at 760 mmHg
  • Melting Point: 165ºC(lit.)
  • Flash Point: 178.3±20.9 °C

Vestitol

(-)-Vestitol is a compound isolated from Glycyrrhiza pallidiflora (Leguminosae)[1].

  • CAS Number: 35878-41-2
  • MF: C16H16O4
  • MW: 272.296
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 418.5±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 206.9±28.7 °C

cholest-5-en-3β,7α-diol

7α-Hydroxycholesterol is a cholesterol oxide and is formed by both enzymatic and non-enzymatic oxidation. 7α-Hydroxycholesterol can be used as a biomarker for lipid peroxidation[1][2].

  • CAS Number: 566-26-7
  • MF: C27H46O2
  • MW: 402.65300
  • Catalog: Others
  • Density: 1.03g/cm3
  • Boiling Point: 515.3ºC at 760mmHg
  • Melting Point: 168-170ºC
  • Flash Point: 214.7ºC

Etofenprox

Etofenprox is a non-ester pyrethroid insecticide. Etofenprox induces toxicity in the housefly M. domestica (LD50 = 23 ng/fly). Formulations containing Etofenprox have been used in the control of agricultural pests.

  • CAS Number: 80844-07-1
  • MF: C25H28O3
  • MW: 376.488
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 481.6±40.0 °C at 760 mmHg
  • Melting Point: 36ºC
  • Flash Point: 165.1±24.6 °C

Oligopeptide-10

Oligopeptide-10 is a bioactive peptide with anti-microbial effect and has been reported used as a cosmetic ingredient[1].

  • CAS Number: 466691-40-7
  • MF: C78H140N20O15
  • MW: 1598.071
  • Catalog: Infection
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 1733.4±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 1002.1±34.3 °C

N-(tert-Butoxycarbonyl)-L-alanine

Boc-L-Ala-OH (Boc-Ala-OH) shows excellent affinity with ATP. Boc-L-Ala-OH contains an amino acid moiety, and an acylamide bond like that of the peptide and protein[1].

  • CAS Number: 15761-38-3
  • MF: C8H15NO4
  • MW: 189.209
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 320.9±25.0 °C at 760 mmHg
  • Melting Point: 79-83 °C(lit.)
  • Flash Point: 147.9±23.2 °C

melamine

Melamine is a metabolite of cyromazine. Melamine is a intermediate for the synthesis of melamine resin and plastic materials[1].

  • CAS Number: 108-78-1
  • MF: C3H6N6
  • MW: 126.120
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 557.5±33.0 °C at 760 mmHg
  • Melting Point: 354 °C
  • Flash Point: 325.3±12.6 °C

6-Monohydroxyflavone

6-Hydroxyflavone is a naturally occurring flavone, with anti-inflammatory activity. 6-Hydroxyflavone exhibits inhibitory effect towards bovine hemoglobin (BHb) glycation. 6-Hydroxyflavone can activate AKT, ERK 1/2, and JNK signaling pathways to effectively promote osteoblastic differentiation. 6-Hydroxyflavone inhibits the LPS-induced NO production[1] [2].

  • CAS Number: 6665-83-4
  • MF: C15H10O3
  • MW: 238.238
  • Catalog: Inflammation/Immunology
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 450.1±45.0 °C at 760 mmHg
  • Melting Point: 234-236 °C(lit.)
  • Flash Point: 176.3±22.2 °C

Carbon-13C

Carbon-13C is the 13C labeled Carbon[1].

  • CAS Number: 14762-74-4
  • MF: CH4
  • MW: 17.03510
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 3550ºC(lit.)
  • Flash Point: N/A

CKS-17

CKS-17 is a synthetic retroviral envelope peptide. CKS-17 has the highly conserved amino acid sequences occurring within the transmembrane envelope protein of many animal and human retroviruses. CKS-17 acts as an immunomodulatory epitope and exhibits suppressive properties for numerous immune functions[1][2][3].

  • CAS Number: 99273-04-8
  • MF: C87H148N26O24
  • MW: 1942.27000
  • Catalog: Inflammation/Immunology
  • Density: 1.41±0.1 g/cm3 (20 °C, 760 mmHg)
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Complanatoside B

Complanatoside B is a P. chinense Fisch flavonoid with potential anti-inflammatory effects[1].

  • CAS Number: 142473-99-2
  • MF: C33H40O20
  • MW: 756.66
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Drimenol

Drimenol is a drimane-type sesquiterpene that can be isolated from Valerian plant[1].

  • CAS Number: 468-68-8
  • MF: C15H26O
  • MW: 222.37
  • Catalog: Others
  • Density: 0.921g/cm3
  • Boiling Point: 298.8ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 106.9ºC

BT-11

BT-11 is an orally available LANCL2 binding compound for treating inflammatory bowel disease.

  • CAS Number: 1912399-75-7
  • MF: C30H24N8O2
  • MW: 528.2
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cyclosporin U

Cyclosporin U (SMP0V32C6L) is an cytostatic agent that plays an important role in preventing rejection of transplanted organs[1].

  • CAS Number: 108027-45-8
  • MF: C61H109N11O12
  • MW: 1188.585
  • Catalog: Inflammation/Immunology
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 1306.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 743.8±34.3 °C

UNC-1079

UNC1079 is the piperidine analog of UNC1021, as a structurally similar but significantly less potent inhibitor for use as a negative control in cellular studies. Target: L3MBTL3The low anticipated affinity of UNC1079 was confirmed, as it demonstrated an activity versus L3MBTL3 of > 10 μM by AlphaScreen, which is >1000-fold weaker than UNC1215. UNC1079 also displays weak binding by ITC.

  • CAS Number: 1418741-86-2
  • MF: C28H42N4O2
  • MW: 466.659
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 640.0±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 264.2±23.9 °C