199859-58-0

199859-58-0 structure

Name: 7-Cyano-7-deaza-2'-deoxy guanosine
Chemical Name: 2-Amino-7-(2-deoxy-α-D-erythro-pentofuranosyl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
CAS Number: 199859-58-0
Molecular Formula: C₁₂H₁₃N₅O₄
Molecular Weight: 291.263
Catalog: Research Areas Others
Create Date: 2018-07-15 04:41:23
Modify Date: 2024-01-11 17:08:40
7-Cyano-7-deaza-2'-deoxy guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

Name	2-Amino-7-(2-deoxy-α-D-erythro-pentofuranosyl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
Synonyms	3H-Pyrrolo[2,3-d]pyrimidine-5-carbonitrile, 2-amino-7-(2-deoxy-α-D-erythro-pentofuranosyl)-4,7-dihydro-4-oxo- 2-Amino-7-(2-deoxy-α-D-erythro-pentofuranosyl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile

Description	7-Cyano-7-deaza-2'-deoxy guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.