Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

N-Benzylglycine ethyl ester

Ethyl 2-(benzylamino)acetate is an important chemical, pesticide and pharmaceutical intermediate with a wide range of applications in the synthesis of chemical products[1].

  • CAS Number: 6436-90-4
  • MF: C11H15NO2
  • MW: 193.242
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 277.0±23.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 121.3±22.6 °C

H-Met-D-Met-OH

H-Met-D-Met-OH is a biologically active peptide.

  • CAS Number: 89680-18-2
  • MF: C10H20N2O3S2
  • MW: 280.40700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-(Iodoacetamido)fluorescein

5-IAF is an idoacetamide derivate of fluoresceine.

  • CAS Number: 63368-54-7
  • MF: C22H14INO6
  • MW: 515.25400
  • Catalog: Dye Reagents
  • Density: 1.95 g/cm3
  • Boiling Point: 788.4ºC at 760 mmHg
  • Melting Point: 265-267ºC (dec.)(lit.)
  • Flash Point: 430.6ºC

N-Acetyl-S-(N-methylcarbamoyl)-L-cysteine-d3

N-Acetyl-S-(N-methylcarbamoyl)-L-cysteine-d3 is the deuterium labeled N-Acetyl-S-(N-methylcarbamoyl)-L-cysteine[1].

  • CAS Number: 131685-10-4
  • MF: C7H9D3N2O4S
  • MW: 223.26
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 151-152°C
  • Flash Point: N/A

Emodin-1-O-beta-gentiobioside

Emodin-1-O-β-gentiobioside is an anthraquinone[1][2].

  • CAS Number: 849789-95-3
  • MF: C27H30O15
  • MW: 594.52
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Oxypeucedanin hydrate

(-)-Oxypeucedanin hydrate ((-)-Prangol) is a derivative of furocoumarin isolated from Ducrosia anethifolia[1].

  • CAS Number: 133164-11-1
  • MF: C16H16O6
  • MW: 304.295
  • Catalog: Cancer
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 544.3±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 283.0±30.1 °C

Valepotriate

Valepotriate, isolated from Valeriana jatamansi Jones, has anti-epileptic and anti-cancer activities[1][2].

  • CAS Number: 18296-44-1
  • MF: C22H30O8
  • MW: 422.469
  • Catalog: Neurological Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 525.9±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 226.5±30.2 °C

H-L-Tyr(2-azidoethyl)-OH hydrochloride

H-L-Tyr(2-azidoethyl)-OH hydrochloride is a unnatural Tyrosine derivative. H-L-Tyr(2-azidoethyl)-OH hydrochloride is a click chemistry reagent containing an azide group[1][2].

  • CAS Number: 1567845-62-8
  • MF: C11H15ClN4O3
  • MW: 286.71
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CLR1501

CLR1501, a fluorescently labeled CLR1404 analog, is a cancer cell-selective fluorescence compound[1][2].

  • CAS Number: 1250963-36-0
  • MF: C38H59BF2N3O4P
  • MW: 701.674
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Benzylstearamide

N-Benzyloctadecanamide (N-Benzylstearamide) is a macamide, a distinct class of secondary metabolites that have so far been found only in Lepidium meyenii Walp. (Maca)[1].

  • CAS Number: 5327-45-7
  • MF: C25H43NO
  • MW: 373.61500
  • Catalog: Others
  • Density: 0.913g/cm3
  • Boiling Point: 525.3ºC at 760 mmHg
  • Melting Point: 93-94 ºC
  • Flash Point: 326.3ºC

Rabacfosadine

Rabacfosadine (GS-9219), a novel prodrug of the nucleotide analogue PMEG, is designed as a cytotoxic agent that preferentially targets lymphoid cells.

  • CAS Number: 859209-74-8
  • MF: C21H35N8O6P
  • MW: 526.52600
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BODIPY 530/550 NHS ester

BODIPY 530/550 NHS ester can be used for the stain of protein. BODIPY 530/550 NHS ester can be used for fluorescence OIM (oblique illumination microscopic) image[1].

  • CAS Number: 216961-93-2
  • MF: C28H22BF2N3O4
  • MW: 513.30
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(Rac)-IDO1-IN-5

(Rac)-IDO1-IN-5 is a racemate of IDO1-IN-5. IDO1-IN-5 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1].

  • CAS Number: 2166616-74-4
  • MF: C23H25FN2O3
  • MW: 396.45
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-BOC-4-(2-Hydroxyethyl)piperazine-d4

1-BOC-4-(2-Hydroxyethyl)piperazine-d4 is the deuterium labeled 1-BOC-4-(2-Hydroxyethyl)piperazine[1].

  • CAS Number: 1219802-10-4
  • MF: C11H18D4N2O3
  • MW: 234.329
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 333.6±32.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 155.5±25.1 °C

(3aS,6S,7aR)-Hexahydro-1-benzofuran-3a,6(4H)-diol

(±)-Cleroindicin E is a natural compound isolated from the herbs of Clerodendrum indicum[1].

  • CAS Number: 165197-71-7
  • MF: C8H14O3
  • MW: 158.195
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 315.5±37.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 144.6±26.5 °C

G12

G12 (Ras 5-17) is a wild-type Ras peptide consisted of amino acids 5-17 (KLVVVGAGGVGKS). G12 can be used as a control of mutant Ras peptides studies (such V12)[1].

  • CAS Number: 162550-82-5
  • MF: C52H95N15O15
  • MW: 1170.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Amino(2-thienyl)acetic acid

(R)-2-Amino-2-(thiophen-2-yl)acetic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 65058-23-3
  • MF: C6H7NO2S
  • MW: 157.190
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 311.8±32.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 142.4±25.1 °C

(S)-methyl 2-amino-3-cyclohexylpropanoate hydrochloride

(S)-methyl 2-amino-3-cyclohexylpropanoate hydrochloride is an alanine derivative[1].

  • CAS Number: 17193-39-4
  • MF: C10H20ClNO2
  • MW: 221.72400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

WAY-634964

WAY-634964 is an active molecule.

  • CAS Number: 157842-34-7
  • MF: C9H7N3O2
  • MW: 189.171
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 346.9±27.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 163.6±23.7 °C

Mast Cell Degranulating (MCD) Peptide HR-1

HR1 is a mastoid protease. HR1 can increase the permeability of human erythrocyte membrane. HR1 can induce cytoplasmic membrane permeation in bacteria and mast cells [1].

  • CAS Number: 80533-94-4
  • MF: C71H133N19O15
  • MW: 1492.93000
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Simufilam hydrochloride

Simufilam (PTI-125) (hydrochloride) is a low toxicity, orally active filamin A (FLNA) activator. Simufilam (hydrochloride) preferentially binds altered FLNA and restores its native conformation, restores receptor and synaptic activities, reduces its a7nAChR/TLR4 associations and downstream pathologies. Simufilam (hydrochloride) can be used for the research of Alzheimer's disease[1].

  • CAS Number: 2480226-07-9
  • MF: C15H22ClN3O
  • MW: 295.81
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MSI-1701

MSI-1701 is an analogue of MSI-1436 which can control weight gain and blood glucose level extracted from patent US 7410959 B1.

  • CAS Number: 390808-64-7
  • MF: C37H72N4O5S
  • MW: 685.06
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

NS-3-008 hydrochloride

NS-3-008 is a novel small-molecule transcriptional inhibitor of G0s2 (G0/G1 switch 2) with IC50 of 2.25 uM; decreases levels of G0s2 and Ccl2 mRNA in the kidneys (5 mg/kg, p.o.); decreases the phosphorylation of Stat5 and p65 protein and suppresses renal inflammation in 5/6Nx mice, ameliorates renal dysfunction in mouse model of chronic kidney disease (CKD).

  • CAS Number: 1172854-54-4
  • MF: C14H24ClN3
  • MW: 269.817
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Bromo-4-(bromomethyl)benzene-d4

1-Bromo-4-(bromomethyl)benzene-d4 is the deuterium labeled 1-Bromo-4-(bromomethyl)benzene[1].

  • CAS Number: 2708280-84-4
  • MF: C7H2D4Br2
  • MW: 253.96
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Raffinose

Raffinose (Melitose), a non-digestible short-chain oligosaccharide, is a trisaccharide composed of galactose, glucose, and fructose and can be found in many plants. Raffinose (Melitose) can be hydrolyzed to D-galactose and sucrose by the enzyme α-galactosidase (α-GAL)[1].

  • CAS Number: 512-69-6
  • MF: C18H32O16
  • MW: 504.437
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 884.8±65.0 °C at 760 mmHg
  • Melting Point: 80ºC
  • Flash Point: 488.9±34.3 °C

5-O-Primeverosylapigenin

5-O-Primeverosylapigenin is a primeverosylapigenin, which can be isolated from Gentianaceae species[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PSB 069

PSB069 bearing a p-chlorophenylamino residue is a potent, well-tolerated and nonselective NTPDases1, 2, 3 inhibitor(Ki=16~18 μM)[1].

  • CAS Number: 78510-31-3
  • MF: C20H12ClN2NaO5S
  • MW: 450.82700
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-O-NITROPHENYLSULFENYL-GLYCINE DI(CYCLOHEXYL)AMMONIUM SALT

N-(2-Nitrophenylsulfenyl)glycine (dicyclohexylammonium) salt is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 7675-47-0
  • MF: C20H31N3O4S
  • MW: 409.54300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(s)-(-)-1-(n-(1-ethoxycarbonyl-3-phen&

(S)-(−)-1-[N-(1-Ethoxycarbonyl-3-phenylpropyl)-N-trifluoroacetyl]-L-lysine is a lysine derivative[1].

  • CAS Number: 130414-30-1
  • MF: C20H27F3N2O5
  • MW: 432.43400
  • Catalog: Others
  • Density: 1.234g/cm3
  • Boiling Point: 587ºC at 760mmHg
  • Melting Point: 133-138ºC(lit.)
  • Flash Point: 308.8ºC

Fepixnebart

Fepixnebart is a humanized IgG4κ antibody targeting TGF-alpha (TGFA).

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A