Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Peptidase

Peptidase(Erepsin) is catalytically active enzyme that cleaves peptide bonds in proteins and peptides by hydrolysis[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sodium Propionate-d3

Sodium Propionate-d3 is the deuterium labeled Sodium Propionate[1].

  • CAS Number: 1210410-35-7
  • MF: C3H2D3NaO2
  • MW: 99.08
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Plantamajoside

Plantamajoside is a phenylpropanoid glycoside isolated from Plantago asiatica L.(Plantaginaceae). Plantamajoside has protective effects on LPS-induced acute lung injury (ALI) mice model. Plantamajoside has the potential for the treatment of pulmonary inflammation[1].

  • CAS Number: 104777-68-6
  • MF: C29H36O16
  • MW: 640.586
  • Catalog: Inflammation/Immunology
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 953.0±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 308.5±27.8 °C

dam Methyltransferase

dam Methyltransferase plays a role in the control of DNA replication in E. coli[1].

  • CAS Number: 69553-52-2
  • MF:
  • MW:
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Acetylcysteine amide

N-Acetylcysteine amide is a cell membranes and blood brain barrier permeant thiol antioxidant and neuroprotective agent.

  • CAS Number: 38520-57-9
  • MF: C5H10N2O2S
  • MW: 162.21000
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7''-O-Methylsciadopitysin

Amentoflavone 7,4',7'',4'''-tetramethyl ether, a biflavone, is a natural product that can be isolated from Selaginella moellendorffii[1].

  • CAS Number: 3778-25-4
  • MF: C34H26O10
  • MW: 594.56
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 813.5±65.0 °C at 760 mmHg
  • Melting Point: 292-294℃
  • Flash Point: 264.5±27.8 °C

Amino(tetrahydro-2H-pyran-4-yl)acetic acid

(R)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 475649-32-2
  • MF: C7H13NO3
  • MW: 159.183
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 316.7±17.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 145.3±20.9 °C

Integerrimine N-oxide

Integerrimine N-oxide, the main pyrrolizidine alkaloid found in the butanolic residue (BR) of Senecio brasiliensis. Prenatal exposure to integerrimine N-oxide induces maternal toxicity, impairment of maternal care and delays in physical and behavioral development of the offspring[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

L-Threonine Benzyl Ester Hydrochloride

H-Thr-Obzl.HCl is a threonine derivative[1].

  • CAS Number: 33645-24-8
  • MF: C11H16ClNO3
  • MW: 245.70300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 128.0 to 132.0 °C
  • Flash Point: N/A

γ-Glutamyl-S-allylcysteine

γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine) is a naturally occurring organosulfur compound found in garlic. γ-Glutamyl-S-allylcysteine has antiglycative effect and shows radical-scavenging and metal-chelating capacities[1][2].

  • CAS Number: 91216-95-4
  • MF: C11H18N2O5S
  • MW: 290.33600
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BODIPY 576/589

BODIPY 576/589 is a long wavelength biological labeled dye[1].

  • CAS Number: 150173-78-7
  • MF: C16H14BF2N3O2
  • MW: 329.11
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3a-Hydroxy-3,3a,7,7a-tetrahydrobenzofuran-2,6-dione

1-Oxo-4-hydroxy-2-en-4-ethylcyclohexa-5,8-olide (compound 8) is a potent anti-ulcer agent[1].

  • CAS Number: 55604-88-1
  • MF: C8H8O4
  • MW: 168.15
  • Catalog: Inflammation/Immunology
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 449.2±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 194.6±22.2 °C

Naloxone fluorescein acetate

Naloxone fluorescein acetate is the fluorescent-derivative of Naloxone. Naloxone is an opioid antagonist. Naloxone is the antidote for reversing the effects of an opioid overdose[1].

  • CAS Number: 2080300-52-1
  • MF: C42H38N4O10S
  • MW: 790.84
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

boc-l-beta-homoarginine(tos)

Boc-β-HoArg(Tos)-OH is an arginine derivative[1].

  • CAS Number: 136271-81-3
  • MF: C19H30N4O6S
  • MW: 442.53000
  • Catalog: Others
  • Density: 1.29g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

dimethylglycine ethyl ester

Ethyl 2-(dimethylamino)acetate is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 33229-89-9
  • MF: C6H13NO2
  • MW: 131.173
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 150.5±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 44.4±0.0 °C

Zilganersen

Zilganersen (ION373) is a glial fibrillary acidic protein (GFAP) inhibitor, an antisense oligonucleotide. Zilganersen can be used in Alexander disease (AxD) research[1][2].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TAPI 2

(R)-TAPI-2 is the isomer of TAPI-2 (HY-100211A). TAPI-2 (TNF Protease Inhibitor 2) is a broad-spectrum inhibitor of matrix metalloprotease (MMP), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM), with an IC50 of 20 μM for MMP[1]. TAPI-2 blocks the entry of infectious SARS-CoV[2].

  • CAS Number: 689284-12-6
  • MF: C19H37N5O5
  • MW: 415.53
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Val-βNA

H-Val-βNA (L-Valine β-naphthylamide) can be used as an aminopeptidase and a Valine arylamidase substrate[1][2].

  • CAS Number: 729-24-8
  • MF: C15H18N2O
  • MW: 242.316
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 457.9±28.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 230.7±24.0 °C

Modified MMAF

Modified MMAF, an ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). Modified MMAF can be used for the targeted treatment of cancer[1].

  • CAS Number: 1352202-47-1
  • MF: C45H73N7O8
  • MW: 840.10
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,5-Dichlorobiphenyl-2′,3′,4′,5′,6′-d5

2,5-Dichlorobiphenyl-2′,3′,4′,5′,6′-d5 is the deuterium labeled 2,5-Dichlorobiphenyl[1].

  • CAS Number: 1219804-50-8
  • MF: C12D10Cl2
  • MW: 235.175
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 320.1±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 144.8±21.4 °C

Glycine, N,N-diethyl-,sodium salt (1:1)

Sodium diethylglycinate is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 5426-55-1
  • MF: C6H12NNaO2
  • MW: 153.15500
  • Catalog: Others
  • Density: 1.013g/cm3
  • Boiling Point: 203.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 76.7ºC

sodium 4-(4-dimethylaminophenyl)diazenylbenzoate

Dabcyl acid sodium (DABCYL sodium) is a nonfluorescent chromophore and a quencher. Dabcyl acid sodium can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions[1][2].

  • CAS Number: 845-46-5
  • MF: C15H14N3NaO2
  • MW: 291.28000
  • Catalog: Others
  • Density: 1.17g/cm3
  • Boiling Point: 482.6ºC at 760 mmHg
  • Melting Point: >300℃
  • Flash Point: 245.6ºC

Neuromedin S (human) trifluoroacetate salt

Neuromedin S (human) is a neuropeptide that contains 33 amino acids.? Neuromedin S (human)has been identified in the brain as an endogenous ligand for the orphan G-protein coupled receptor (GPCR) FM-4/TGR-1 and acts on the neuromedin U (NMU) receptor 2 (NMUR2) in the regulation of body weight homeostasis[1].

  • CAS Number: 1138204-27-9
  • MF: C173H265N53O44
  • MW: 3791.34
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-Cys(Trt)-OH

(R)-2-((tert-Butoxycarbonyl)amino)-3-(tritylthio)propanoic acid is a cysteine derivative[1].

  • CAS Number: 21947-98-8
  • MF: C27H29NO4S
  • MW: 463.589
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 610.9±55.0 °C at 760 mmHg
  • Melting Point: 143-146 °C(lit.)
  • Flash Point: 323.3±31.5 °C

Bryonamide A

Bryonamide A is a natural compound isolated from red algae Bostrychia radicans (Rhodomelaceae)[1].

  • CAS Number: 75268-14-3
  • MF: C9H11NO3
  • MW: 181.18900
  • Catalog: Others
  • Density: 1.273g/cm3
  • Boiling Point: 451.2ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 226.7ºC

H-D-Glu(OBzl)-OH

H-D-Glu(OBzl)-OH is a glutamic acid derivative[1].

  • CAS Number: 2578-33-8
  • MF: C12H15NO4
  • MW: 237.252
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 426.1±45.0 °C at 760 mmHg
  • Melting Point: 176ºC
  • Flash Point: 211.5±28.7 °C

Droxicainide

Droxicainide is an antiarrhythmic agent.

  • CAS Number: 78289-26-6
  • MF: C16H24N2O2
  • MW: 276.37400
  • Catalog: Cardiovascular Disease
  • Density: 1.133g/cm3
  • Boiling Point: 456.2ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 229.7ºC

(+)-Guaiacin

(+)-Guaiacin is a compound extracted of the bark of Machilus wangchiana Chun. (Lauraceae). (+)-Guaiacin shows potent in vitro activities against the release of β-glucuronidase in rat polymorphonuclear leukocytes (PMNs) induced by platelet-activating factor (PAF) [1].

  • CAS Number: 88547-66-4
  • MF: C20H24O4
  • MW: 328.40
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Decursin

Decursin is an anticancer agent, with potential anti-inflammatory activity.

  • CAS Number: 5928-25-6
  • MF: C19H20O5
  • MW: 328.359
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 469.4±45.0 °C at 760 mmHg
  • Melting Point: 93-94ºC
  • Flash Point: 206.6±28.8 °C

Angiotensin Itrifluoroacetate

Angiotensin 1 (Human) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE).

  • CAS Number: 484-42-4
  • MF: C62H89N17O14
  • MW: 1296.48000
  • Catalog: Peptides
  • Density: 1.43 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A