Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Droxicainide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

78289-26-6

78289-26-6 structure

78289-26-6 structure

Name: Droxicainide
Chemical Name: N-(2,6-dimethylphenyl)-1-(2-hydroxyethyl)piperidine-2-carboxamide
CAS Number: 78289-26-6
Molecular Formula: C₁₆H₂₄N₂O₂
Molecular Weight: 276.37400
Catalog: Research Areas Cardiovascular Disease
Create Date: 2016-02-26 05:41:31
Modify Date: 2024-01-11 18:00:02
Droxicainide is an antiarrhythmic agent.

Name	N-(2,6-dimethylphenyl)-1-(2-hydroxyethyl)piperidine-2-carboxamide
Synonyms	als-1249 unii-j6w196lmv3 Droxicainide

Description	Droxicainide is an antiarrhythmic agent.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cardiovascular Disease
In Vivo	In coronary artery occlusion study, Droxicainide reduces hypoperfused area that evolves to necrosis, and reduces the infarct size in dogs[1]. Droxicainide decreases the sinus node, atrial and ventricular excitability and contractile force and increases the refractoriness in the study of spontaneously beating atria, electrically stimulated atria and papillary muscles isolated from rats[2].
References	[1]. Faria DB, et al. Effects of lidocaine and droxicainide on myocardial necrosis: a comparative study. J Am Coll Cardiol. 1983 Jun;1(6):1447-52. [2]. Helgesen KG, et al. Comparison of electrophysiological and mechanical effects of droxicainide and lidocaine on heart muscle isolated from rats. Acta Pharmacol Toxicol (Copenh). 1984 Oct;55(4):303-7.

Density	1.133g/cm3
Boiling Point	456.2ºC at 760 mmHg
Molecular Formula	C₁₆H₂₄N₂O₂
Molecular Weight	276.37400
Flash Point	229.7ºC
Exact Mass	276.18400
PSA	56.06000
LogP	2.67610
Index of Refraction	1.578
Storage condition	2-8℃