Boc-Ala-OMe is an alanine derivative[1].
HSDAVFTDNYTRLRRQLAVRRYLNSILN-NH2 is an anti-inflammatory peptide[1].
Henriol B (Chloramultilide D) is a dimeric sesquiterpenoid that can be isolated from C. spicatus[1].
Odronextamab is a hinge-stabilised, fully human IgG4-based CD20 × CD3 bispecific antibody that binds CD3 on T cells and CD20 on B cells[1].
N-(7-Nitrobenzofurazan-4-yl)phallacidin is a fluorochrome. N-(7-Nitrobenzofurazan-4-yl)phallacidin can be used visualizing probe for actin[1].
2-Chlorobenzoic acid-d4 is the deuterium labeled 2-Chlorobenzoic acid[1].
2-Hydroxypropyl acrylate (HPA) is a severe irritant and corrosive to the skin. 2-Hydroxypropyl acrylate (HPA) is extensively applied in fibre, adhesives, rubber industry, paints and coatings industry[1][2].
Flumethasone is a corticosteroid for topical use, in combination with Clioquinol for the treatment of otitis externa and otomycosis. Flumethasone shows fully 420 times the potency of cortisone in an animal model for anti-inflammatory activity.
Anti-virus agent 1 (compound 4i), a phosphoramidate prodrug of GS-5734 (HY-104077; Remdesivir), has potent antiviral activity. Anti-virus agent 1 is used for the research of coronavirus and Ebola virus (EBOV)[1][2].
1,1′-Disinomenine is an alkaloid that can be isolated from the stems of Sinomenium acutum. 1,1′-Disinomenine shows weak inhibition against A549 and Hela cells[1].
Sepofarsen (QR-110) is an RNA antisense oligonucleotide targeting to the p.Cys998X mutation (also known as the c.2991+1655A>G mutation) in the CEP290 gene.
Lurbinectedin (PM01183) is a new DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC50 values of 1.25 and 1.16 nM, respectively.
RG3039 (PF-06687859) is an orally bioavailable and brain-penetrant DcpS inhibitor with an IC50 of 0.069 nM.
Isomedicarpin is a natural product that can be found in Erythrina[1].
DNDI-6148 is a novel preclinical candidate for the treatment of visceral leishmaniasis.
Octotiamine (TATD) is a vitamin B1 analogue, a component of vitamin complex. Octotiamine can be used for the research of vitamin B1 deficiency[1].
Methyl palmitate-d31 is the deuterium labeled Methyl palmitate. Methyl palmitate, an acaricidal compound occurring in green walnut husks, inhibits phagocytic activity and immune response. Methyl palmitate also posseses anti-inflammatory and antifibrotic effects[1][2][3].
γ-Cadinene is a natural product that can be found in Tabernaemontana catharinensis[1].
6β-Hydroxytomentosin, a sesquiterpenoid, can be found in flowers of Inula japonica. 6β-Hydroxytomentosin exhibits weak cytotoxicities against A549, SK-OV-3, HepG-2 and HT-29 cell lines[1][2].
Pratensein-7-O-β-D-glucopyranoside is a new isoflavone[1].
Poricoic acid B, isolated from Poria cocos, possesses anti-tumor activity[1].
Roseoside is a compound isolated from the leaves of Elaeocarpus japonicus[1].
Thielocin B1 is a protein-protein interaction inhibitor of PAC3 homodimer. Thielocin B1 was isolated as a novel phospholipase A2 inhibitor from the fermentation broth of Thielavia terricola RF-143.
Fuscaxanthone C is an xanthone isolated from the stem bark of Garcinia fusca[1].
(S)-(+)-N-3-Benzylnirvanol is a drug used formetabolic regulation. (S)-(+)-N-3-Benzylnirvanol has the activity of inhibitinghuman P450 enzyme. (S)-(+) -n-3-benzylnirvanol can be used to study druginteractions during drug metabolism [1].
Bretylium (tosylate) is an inhibitor of the presynaptic release of vasoconstrictor neurotransmitters. It is the sympathetic nerve and adrenergic ganglion blocking agent .(1) Bretylium tosylate inhibits adrenergic function presynaptically only after an initial release in neurotransmitter substance.(2) The reference for administration dose is 15 mg/kg (I.P).
Tabersonine is an indole alkaloid mainly isolated from Catharanthus roseus. Tabersonine disrupts Aβ(1-42) aggregation and ameliorates Aβ aggregate-induced cytotoxicity. Tabersonine has anti-inflammatory activities and acts as a potential therapeutic candidate for the treatment of ALI/ARDS[1].
Jatrorrhizine chloride is a potent and orally active uptake-2 transporter inhibitor, it can be isolated from various Chinese medicinal plants[1]. Jatrorrhizine chloride exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of MAPK pathway in HT22 hippocampal neurons[2].
Xipamide-d6 is the deuterium labeled Xipamide. Xipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE)[1][2].