(R)-Linezolid

Modify Date: 2024-01-28 17:22:19

(R)-Linezolid Structure
(R)-Linezolid structure
Common Name (R)-Linezolid
CAS Number 872992-20-6 Molecular Weight 337.346
Density 1.3±0.1 g/cm3 Boiling Point 585.5±50.0 °C at 760 mmHg
Molecular Formula C16H20FN3O4 Melting Point N/A
MSDS N/A Flash Point 307.9±30.1 °C

 Use of (R)-Linezolid


(R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis[1][2].

 Names

Name N-[[(5R)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide
Synonym More Synonyms

 (R)-Linezolid Biological Activity

Description (R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis[1][2].
Related Catalog
References

[1]. Bednarek E, et al. NMR and molecular modeling study, as complementary techniques to capillary electrophoresis method to elucidate the separation mechanism of linezolid enantiomers. J Chromatogr A. 2008 Jun 6;1193(1-2):164-71.

[2]. Clemett D, et al. Linezolid. Drugs. 2000 Apr;59(4):815-27; discussion 828.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 585.5±50.0 °C at 760 mmHg
Molecular Formula C16H20FN3O4
Molecular Weight 337.346
Flash Point 307.9±30.1 °C
Exact Mass 337.143799
PSA 74.60000
LogP 0.30
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.554

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

Acetamide, N-[[(5R)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-
UNII-ISQ9I6J12J
N-({(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide
Zivoxid
N-({(5R)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide
Linezolid Impurity 1