Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Fmoc-Lys(Me)3-OH Chloride

Fmoc-Lys(Me)3-OH Chloride is a lysine derivative[1].

  • CAS Number: 201004-29-7
  • MF: C24H31ClN2O4
  • MW: 446.967
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

poly (arginyl-glycyl-aspartyl-threonine)

RGDT is a synthetic peptide. RGDT can be used in the research of cancer[1][2].

  • CAS Number: 93675-01-5
  • MF: C10H12AsNO6
  • MW: 317.127
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

γ-Glutamyl-S-1-propenyl cysteine

γ-Glutamyl-S-1-propenyl cysteine is a compound isolated from garlic[1].

  • CAS Number: 91216-96-5
  • MF: C11H18N2O5S
  • MW: 290.34
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Raloxifene 6,4'-Bis-β-D-glucuronide

Raloxifene 6,4'-Bis-β-D-glucuronide (compound IV) is a metabolite of Raloxifene. Raloxifene is a selective estrogen receptor antagonist for the prevention of osteoporosis[1].

  • CAS Number: 182507-20-6
  • MF: C40H43NO16S
  • MW: 827.84700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

FMOC-ASP(OTBU)-OH

Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis[1].

  • CAS Number: 71989-14-5
  • MF: C23H25NO6
  • MW: 411.448
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 620.8±55.0 °C at 760 mmHg
  • Melting Point: 148-150 °C (dec.)
  • Flash Point: 329.3±31.5 °C

[Asu1,6]-Oxytocin

[Asu1,6]-Oxytocin is an analog of oxytocin. [Asu1,6]-Oxytocin reverses insulin resistance and glucose intolerance prior to reduction of obesity. [Asu1,6]-Oxytocin has the potential for the research of obesity and diabetes[1].

  • CAS Number: 14317-68-1
  • MF: C45H69N11O12
  • MW: 956.09600
  • Catalog: Metabolic Disease
  • Density: 1.216g/cm3
  • Boiling Point: 1475.3ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 846ºC

Methyl acetyl-D-phenylalaninate

Methyl acetyl-D-phenylalaninate is a phenylalanine derivative[1].

  • CAS Number: 21156-62-7
  • MF: C12H15NO3
  • MW: 221.25200
  • Catalog: Others
  • Density: 1.117g/cm3
  • Boiling Point: 391ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 190.3ºC

1,3-Dibromo-1,3-dichloroacetone

1,3-Dibromo-1,3-dichloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant[1].

  • CAS Number: 62874-84-4
  • MF: C3H2Br2Cl2O
  • MW: 284.76100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Metazachlor

Metazachlor is a herbicide of the chloroacetamide class. Metazachlor is an inhibitor of the synthesis of long chain fatty acids and has an effect on cell division or tissue differentiation in the germinating and emerging weed target species[1].

  • CAS Number: 67129-08-2
  • MF: C14H16ClN3O
  • MW: 277.74900
  • Catalog: Others
  • Density: 1.19 g/cm3
  • Boiling Point: 439.2ºC at 760 mmHg
  • Melting Point: 74-78°C
  • Flash Point: 2 °C

1-Bromooctane-d17

1-Bromooctane-d17 is the deuterium labeled 1-Bromooctane[1].

  • CAS Number: 126840-36-6
  • MF: C8BrD17
  • MW: 210.22900
  • Catalog: Others
  • Density: 1.217 g/mL at 25ºC
  • Boiling Point: 201ºC(lit.)
  • Melting Point: -55ºC(lit.)
  • Flash Point: 173 °F

BAX-IN-1

BAX-IN-1 is a potential, selective inhibitor of Bcl-2-associated X protein (BAX).

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

20-Hydroxyganoderic acid G

20-Hydroxyganoderic Acid G is a lanostane triterpenoid obtained from the EtOH extract of fruiting bodies of the Ganoderma curtisii. 20-Hydroxyganoderic Acid G inhibits BV-2 microglia cells activated by LPS with an IC50 of 21.33 μM. 20-Hydroxyganoderic Acid G has therapeutic potential in the drug discovery of nerve inflammation diseases associated with microglia activated by LPS[1].

  • CAS Number: 400604-12-8
  • MF: C30H44O9
  • MW: 548.67
  • Catalog: Inflammation/Immunology
  • Density: 1.31±0.1 g/cm3(Predicted)
  • Boiling Point: 760.1±60.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

N-O-NITROPHENYLSULFENYL-L-HYDROXYPROLINE DI(CYCLOHEXYL)AMMONIUM SALT

N-(2-Nitrophenylsulfenyl)-L-hydroxyproline (dicyclohexylammonium) salt is a proline derivative[1].

  • CAS Number: 7675-54-9
  • MF: C23H35N3O5S
  • MW: 465.60600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Polyoxyethylene lauryl ether

Polidocanol is a sclerosing agent used successfully to treat extremity and esophageal varices and telangiectasias.

  • CAS Number: 9002-92-0
  • MF: (C2H4O)nC12H26O
  • MW: 1199.543
  • Catalog: Cardiovascular Disease
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 960.0±60.0 °C at 760 mmHg
  • Melting Point: 41-45 °C(lit.)
  • Flash Point: 534.4±32.9 °C

Lofepramine-d3

Lofepramine-d3 (Lopramine-d3) is the deuterium labeled Lofepramine. Lofepramine (Lopramine) is a potent tricyclic antidepressant and is extensively metabolised to Desipramine. The antidepressant activity of Lofepramine stems from the facilitation of noradrenergic neurotransmission by uptake inhibition. Lofepramine may also potentiate serotoninergic neurotransmission by inhibition of the neuronal uptake of serotonin and the enzyme tryptophan pyrrolase. Lofepramine has significant anxiolytic efficacy in addition to its antidepressant properties[1].

  • CAS Number: 1185083-78-6
  • MF: C26H24D3ClN2O
  • MW: 421.98
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tremelimumab

Tremelimumab (Ticilimumab) is a fully humanized monoclonal antibody specific for cytotoxic T-lymphocyte antigen-4 (CTLA-4) and can be used for metastatic melanoma research[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Scoparone

Scoparone is isolated from Artemisia capillaris, has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities[1].

  • CAS Number: 120-08-1
  • MF: C11H10O4
  • MW: 206.195
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 369.2±42.0 °C at 760 mmHg
  • Melting Point: 145°C
  • Flash Point: 166.8±27.9 °C

eucommiol

Eucommiol is a natural product that can be isolated from the roasted leaves of E. ulmoides. Eucommiol inhibits growth of Molt 4B cells. Eucommiol reduces spontaneous activity and increases the sleep ratio in mice[1][2][3].

  • CAS Number: 55930-44-4
  • MF: C9H16O4
  • MW: 188.22100
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

bacteriopheophytin

Bacteriopheophytin, a photosynthetic pigment, is a bacterial demagnetised chlorophyll composed of bacterial chlorophyll in which two hydrogen atoms replace the magnesium center. Bacteriopheophytin acts as an electron acceptor in the purple bacterial reaction center (RC) and is involved in electron transfer[1].

  • CAS Number: 17453-58-6
  • MF: C55H76N4O6
  • MW: 889.21500
  • Catalog: Others
  • Density: 1.095g/cm3
  • Boiling Point: 997.8ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 557.2ºC

11-Deoxymogroside V

11-Deoxymogroside V is a cucurbitane triterpene glycoside[1].

  • CAS Number: 1707161-17-8
  • MF: C60H102O28
  • MW: 1271.435
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Binifibrate

Binifibrate is an active compound and has a beneficial effect on lipoprotein metabolism. Binifibrate can be used for the research of hyperlipidemia[1][2].

  • CAS Number: 69047-39-8
  • MF: C25H23ClN2O7
  • MW: 498.91200
  • Catalog: Metabolic Disease
  • Density: 1.315g/cm3
  • Boiling Point: 629.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 334.3ºC

(22R)-2β,3β,20,22,25-Pentahydroxy-5β-cholesta-8,14-dien-6-one

Podecdysone B is a phytoecdysone isolated from Cyanotis arachnoidea[1].

  • CAS Number: 22612-27-7
  • MF: C27H42O6
  • MW: 462.61900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PCSK9 modulator-2

PCSK9 modulator-2 (Compound 1) is a potent modulator of PCSK9 with an EC50 value of 202 nM. PCSK9 is a recently validated target for lowering low-density lipoprotein cholesterol (LDL-C). PCSK9 modulator-2 has the potential for the research of hyperlipidemia[1].

  • CAS Number: 2365416-53-9
  • MF: C17H12F2N2
  • MW: 282.29
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(4R)-1-Methyl-4-propyl-L-proline methyl ester-d3

(4R)-1-Methyl-4-propyl-L-proline methyl ester-d3 is the deuterium labeled (4R)-1-Methyl-4-propyl-L-proline methyl ester[1].

  • CAS Number: 1356837-90-5
  • MF: C10H16D3NO2
  • MW: 188.28
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Borax

Sodium tetraborate decahydrate can be used as an excipient, such as preservative, mordant. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

  • CAS Number: 1303-96-4
  • MF: B4H20Na2O17
  • MW: 381.37
  • Catalog: Others
  • Density: 1.73 g/mL at 25 °C(lit.)
  • Boiling Point: 320°C
  • Melting Point: 75 °C
  • Flash Point: N/A

3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid

2-O-β-D-Glucosyloxy-4-methoxybenzene propanoic acid is a glucoside derivative[1].

  • CAS Number: 477873-63-5
  • MF: C16H22O9
  • MW: 358.34
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 624.6±55.0 °C at 760 mmHg
  • Melting Point: 168-169℃ (acetone )
  • Flash Point: 228.0±25.0 °C

Myricetin-3-O-rutinoside

Myricetin-3-O-rutinoside (Compound 3) is a natural product that can be isolated from Picea abies[1].

  • CAS Number: 41093-68-9
  • MF: C27H30O17
  • MW: 626.52
  • Catalog: Others
  • Density: 1.89±0.1 g/cm3(Predicted)
  • Boiling Point: 1053.4±65.0 °C(Predicted)
  • Melting Point: 190-192 °C
  • Flash Point: N/A

6H-Dibenzo[b,d]pyran-6-one

3,4-Benzocoumarin is a kind of the expanded structure of coumarin derivatives.Coumarin is a chemical compound in the benzopyrone chemical class that can be found in many natural species. Coumarins possess variety of biological activities and unique photophysical properties[1]. 3,4-Benzocoumarin, a AOH‐like compound , has the sensibility of the antibody with an IC50 of 919.2 ng/mL[2].

  • CAS Number: 2005-10-9
  • MF: C13H8O2
  • MW: 196.20100
  • Catalog: Others
  • Density: 1.277g/cm3
  • Boiling Point: 354.7ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 148ºC

PL-3994

PL-3994 is a natriuretic peptide receptor-A (NPR-A) agonist that is resistant to neutral endopeptidase and acts as a bronchodilator. PL-3994 produces concentration-dependent relaxation of pre-contracted guinea-pig trachea with an IC50 value of 42.7 nM[1].

  • CAS Number: 952295-80-6
  • MF: C82H127N27O20S2
  • MW: 1875.18
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

25-O-methylcimigenol-3-O-beta-D-xylopyranoside

25-O-Methylcimigenol-3-O-D-xylopyranoside is an active compound. 25-O-Methylcimigenol-3-O-D-xylopyranoside can be used for the research of various biochemical [1].

  • CAS Number: 27994-13-4
  • MF: C36H58O9
  • MW: 634.840
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 730.2±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 395.4±32.9 °C