Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

β-Cyclocitral

β-Cyclocitral, a volatile oxidized derivative of β-carotene, is a grazer defence signal unique to the Cyanobacterium Microcystis. β-Cyclocitral, one of the predominant volatile terpenoid compounds, can upregulate the expression of defence genes to enhance excess light (EL) acclimation. β-Cyclocitral is a powerful repellent[1][2][3].

  • CAS Number: 432-25-7
  • MF: C10H16O
  • MW: 152.23300
  • Catalog: Others
  • Density: 0.947g/cm3
  • Boiling Point: 212.1ºC at 760mmHg
  • Melting Point: 62-63ºC
  • Flash Point: 76.9ºC

Antiviral agent 27

Antiviral agent 27 (Compound 12) has notable activity against the Ebola virus (EC50: 14 nM)[1].

  • CAS Number: 2270947-36-7
  • MF: C24H34N2O
  • MW: 366.54
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-PHTHALOYL-DL-METHIONINE

N-Phthaloyl-DL-methionine is a Methionine (HY-13694) derivative[1].

  • CAS Number: 52881-96-6
  • MF: C13H13NO4S
  • MW: 279.31200
  • Catalog: Others
  • Density: 1.422g/cm3
  • Boiling Point: 492ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 251.4ºC

cis-Vaccenic acid

cis-Vaccenic acid, the antiviral extract from Rhodopseudomonas capsulate and the predominant active component of Rhodopseudomonas capsulate[1], acts a potential fetal hemoglobin inducer[2].

  • CAS Number: 506-17-2
  • MF: C18H34O2
  • MW: 282.461
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 398.2±11.0 °C at 760 mmHg
  • Melting Point: 14-15ºC(lit.)
  • Flash Point: 295.0±14.4 °C

Cedrusin

Cedrusin is a benzofuran derivative that can be isolated from Styrax suberifolius[1].

  • CAS Number: 75775-36-9
  • MF: C19H22O6
  • MW: 346.37
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 558.1±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 291.3±30.1 °C

[Ala2] Met-Enkephalinamide

[Ala2] Met-Enkephalinamide is an active peptide. [Ala2] Met-Enkephalinamide can be used for the research of various biochemical studies[1].

  • CAS Number: 64240-07-9
  • MF: C28H38N6O6S
  • MW: 586.70
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,3-Dimethylpyridine-d9

2,3-Dimethylpyridine-d9 is the deuterium labeled 2,3-Dimethylpyridine[1].

  • CAS Number: 350818-65-4
  • MF: C7H9N
  • MW: 107.153
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 160.7±9.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 45.4±7.9 °C

Acetylthevetin A

Acetylthevetin A is a natural product isolated from oleander (Cascabela thevetioides)[1].

  • CAS Number: 1356494-03-5
  • MF: C44H66O20
  • MW: 914.99
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sclareol glycol

Sclareol glycol is the precursor of ambroxide. Hyphozyma roseonigra ATCC 20624 was the only reported strain capable of degrading sclareol to the main product of sclareol glycol[1].

  • CAS Number: 55881-96-4
  • MF: C16H30O2
  • MW: 254.408
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 315.3±10.0 °C at 760 mmHg
  • Melting Point: 131-132ºC
  • Flash Point: 132.8±13.6 °C

Tyroserleutide (YSL)

Tyroserleutide (YSL), isolated from the degradation products of porcine spleen[1], is a small molecular tripeptide which inhibits tumor growth both in vitro and in vivo[2].

  • CAS Number: 138168-48-6
  • MF: C18H27N3O6
  • MW: 381.423
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 763.8±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 415.7±32.9 °C

Properdistatin

Properdistatin is a peptide derived from the thrombospondin 1 (TSP-1) domain of properdin. Properdistatin inhibits angiogenesis and improves vascular function. Properdistatin has the potential for the research of melanoma[1].

  • CAS Number: 945373-85-3
  • MF: C89H149N33O27S2
  • MW: 2177.47
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Biotin-myelin basic protein (94-102)

Biotin-myelin basic protein (94-102) is a peptide fragemt. Myelin basic protein is responsible for adhesion of the cytosolic surfaces of multilayered compact myelin, it plays an important role in the process of myelination of nerves in the nervous system. Myelin basic protein also acts as a membrane actin-binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocytes and tight junctions in myelin[1].

  • CAS Number: 923949-88-6
  • MF: C49H84N20O13S
  • MW: 1193.38
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-(1-Naphthalenesulfonyl)-L-phenylalanine

N-(1-Naphthalenesulfonyl)-L-phenylalanine is a phenylalanine derivative[1].

  • CAS Number: 90291-46-6
  • MF: C19H17NO4S
  • MW: 355.40800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 141ºC
  • Flash Point: N/A

Fmoc-D-Bip(4,4)-OH

Fmoc-D-Bip(4,4’)-OH is an alanine derivative[1].

  • CAS Number: 205526-38-1
  • MF: C30H25NO4
  • MW: 463.524
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 700.7±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 377.6±32.9 °C

Pyrithioxin

Pyrithioxin is a neurodynamic compound, combined with a short period of hyperventilation (HV) was applied in cerebral infarct patients with Hemiplegia.

  • CAS Number: 1098-97-1
  • MF: C16H20N2O4S2
  • MW: 368.47100
  • Catalog: Neurological Disease
  • Density: 1.448 g/cm3
  • Boiling Point: 742.8ºC at 760 mmHg
  • Melting Point: 54-57 °C(lit.)
  • Flash Point: >230 °F

2-Desoxypleniradin-L-α-arabinopyranoside, 2-acetate

2-Desoxypleniradin-L-α-arabinopyranoside, 2-acetate is an active compound. 2-Desoxypleniradin-L-α-arabinopyranoside, 2-acetate can be isolated from Helenium amarum[1].

  • CAS Number: 97996-02-6
  • MF: C22H30O8
  • MW: 422.47
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Alpha-ketoisocaproic acid-13C2 sodium

Alpha-ketoisocaproic acid-13C2 (sodium) is the 13C labeled Alpha-ketoisocaproic acid sodium[1].

  • CAS Number: 2483736-09-8
  • MF: C413C2H10NaO3
  • MW: 155.12
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Bis(2-hydroxypropyl)nitrosamine

N-Bis(2-hydroxypropyl)nitrosamine is an agent with carcinogenic activity.

  • CAS Number: 53609-64-6
  • MF: C6H14N2O3
  • MW: 162.187
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 352.4±27.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 166.9±23.7 °C

2,2-dimethyl-8-prenylchromene 6-carboxylic acid

2,2-Dimethyl-8-prenylchromene 6-carboxylic acid (compound 2) is a natural product that can be found in Piper aduncum[1].

  • CAS Number: 151731-50-9
  • MF: C17H20O3
  • MW: 272.34
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 427.0±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 153.8±22.2 °C

TOPS

TOPS, a Trinder's reagent, is a novel highly water-soluble aniline derivative; are widely used in diagnostic tests and biochemical tests.

  • CAS Number: 40567-80-4
  • MF: C12H18NNaO3S
  • MW: 279.331
  • Catalog: Biochemical Assay Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Myt1-IN-1

Myt1-IN-1 is a potent Myt1 inhibitor with an IC50 of <10 nM. Myt1-IN-1 has anticancer effects (WO2021195782A1; compound 132)[1].

  • CAS Number: 2719749-02-5
  • MF: C16H15ClN4O2
  • MW: 330.77
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Autoinducing Peptide I trifluoroacetate salt

Autoinducing Peptide I is a cyclic octapeptide secreted by Staphylococcus aureus and can be used in vaccine research[1].

  • CAS Number: 200010-29-3
  • MF: C43H60N8O13S2
  • MW: 961.112
  • Catalog: Infection
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 1434.3±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 821.2±34.3 °C

FDI-6

FDI-6 is an inhibitor of FOXM1. FDI-6 binds directly to FOXM1 protein, to displace FOXM1 from genomic targets in MCF-7 breast cancer cells, and induce concomitant transcriptional down-regulation.

  • CAS Number: 313380-27-7
  • MF: C19H11F4N3OS2
  • MW: 437.43400
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

A 1120

A 1120 is a high affinity non-retinoid ligand for retinol-binding protein 4 (RBP4) with the ki value of 8.3 nM[1].

  • CAS Number: 1152782-19-8
  • MF: C20H19F3N2O3
  • MW: 392.37
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

((4-Chloro-3-(trifluoromethyl)phenyl)sulfonyl)glycine

((4-Chloro-3-(trifluoromethyl)phenyl)sulfonyl)glycine is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 612043-42-2
  • MF: C9H7ClF3NO4S
  • MW: 317.66900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fosdenopterin

Fosdenopterin (Precursor Z) is a synthetic cyclic pyranopterin monophosphate (cPMP). Fosdenopterin can be used for the research of molybdenum cofactor deficiency (MoCD) type A[1].

  • CAS Number: 150829-29-1
  • MF: C10H14N5O8P
  • MW: 363.22
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Thenoyltrifluoroacetone

2-Thenoyltrifluoroacetone is a chelating agent. 2-Thenoyltrifluoroacetone can be used for the complexation of various metal ions including Mn(II), Co(III), Ni(II), et al.. 2-Thenoyltrifluoroacetone possesses antitubercular and cytotoxic activities. 2-Thenoyltrifluoroacetone is also used as common inhibitor of mitochondrial electron flux and to analyze the endothelial cell dysfunction. Besides, copper (II) complex of 2-Thenoyltrifluoroacetone has anticancer activity against K562[1].

  • CAS Number: 326-91-0
  • MF: C8H5F3O2S
  • MW: 222.18
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 227.5±0.0 °C at 760 mmHg
  • Melting Point: 40-44 °C(lit.)
  • Flash Point: 111.7±0.0 °C

S07-2008

S07-2008 is a selective aldo-keto reductase family 1 member C3 (AKR1C3) inhibitor with an IC50 of 0.16 μM. S07-2008 shows anticancer activities[1].

  • CAS Number: 1090816-80-0
  • MF: C21H23N3O5S
  • MW: 429.49
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-Methyl-d3-1-octyl-7,8,8,8-d4 Alcohol

7-Methyl-d3-1-octyl-7,8,8,8-d3 Alcohol is the deuterium labeled 7-Methyl-d3-1-octyl Alcohol[1].

  • CAS Number: 1794753-02-8
  • MF: C9H13D7O
  • MW: 151.30
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SPPHPSPAFSPAFDNLYYWDQ

SPPHPSPAFSPAFDNLYYWDQ is a multi-epitope class II rat HER2/neu peptide. SPPHPSPAFSPAFDNLYYWDQ can be used for the research class II HER2-DC1 vaccine studies[1].

  • CAS Number: 1443436-80-3
  • MF: C116H150N26O33
  • MW: 2436.59
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A