Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Ezetimibe phenoxy glucuronide-d4-1

Ezetimibe phenoxy glucuronide-d4-1 is the deuterium labeled Ezetimibe phenoxy glucuronide. Ezetimibe phenoxy glucuronide (Ezetimibe glucuronide) is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity[1]. Ezetimibe is a potent cholesterol absorption inhibitor[2][3].

  • CAS Number: 2798007-90-4
  • MF: C30H25D4F2NO9
  • MW: 589.57
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-O-Methylrosmanol

7-Methoxyrosmanol (7-O-Methoxyrosmanol), a phenolic diterpene isolated from rosemary, suppresses the cAMP responsiveness of PEPCK and G6Pase promoters[1].

  • CAS Number: 113085-62-4
  • MF: C21H28O5
  • MW: 360.444
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 542.3±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 189.7±23.6 °C

Ivabradine (D3 Hydrochloride)

Ivabradine D3 Hydrochloride is the deuterium labeled Ivabradine hydrochloride. Ivabradine hydrochloride is a new If inhibitor with IC50 of 2.9 μM, and used as a pure heart rate lowering agent.

  • CAS Number: 1217809-61-4
  • MF: C27H34D3ClN2O5
  • MW: 508.06
  • Catalog: Adrenergic Receptor
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Trometamol

Trometamol is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. Trometamol is an effective amine compound for pH control in the physiological range[1].

  • CAS Number: 77-86-1
  • MF: C4H11NO3
  • MW: 121.135
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 357.0±37.0 °C at 760 mmHg
  • Melting Point: 167-172 °C(lit.)
  • Flash Point: 169.7±26.5 °C

N,N'-Bis(benzyloxycarbonyl)hydrazine

Dibenzyl hydrazodicarboxylate (Dibenzyl hydrazine-1,2-dicarboxylate) is a protein cross-linking agent.

  • CAS Number: 5394-50-3
  • MF: C16H16N2O4
  • MW: 300.30900
  • Catalog: Others
  • Density: 1.248g/cm3
  • Boiling Point: 462.4ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 233.5ºC

Pseudobufarenogin

Pseudobufarenogin is a natural compound extracted from toad species with unknown details.

  • CAS Number: 17008-69-4
  • MF: C24H32O6
  • MW: 416.507
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 635.8±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 218.7±25.0 °C

Boc-N-Me-Val-OH

(2S)-2-[[(tert-Butoxy)carbonyl](methyl)amino]-3-methylbutanoic acid is a valine derivative[1].

  • CAS Number: 45170-31-8
  • MF: C11H21NO4
  • MW: 231.289
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 322.4±21.0 °C at 760 mmHg
  • Melting Point: 52.9ºC (dec.)
  • Flash Point: 148.8±22.1 °C

Tetrabutylammonium Dibromochloride

Tetrabutylammonium Dibromochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 64531-21-1
  • MF: C16H36Br2ClN
  • MW: 437.72500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 67ºC
  • Flash Point: N/A

N-(3-Mercapto-2-methylpropanoyl)glycine-d5

N-(3-Mercapto-2-methylpropanoyl)glycine-d5 is the deuterium labeled N-(3-Mercapto-2-methylpropanoyl)glycine[1].

  • CAS Number: 1184993-97-2
  • MF: C6H6D5NO3S
  • MW: 182.25
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SUCROSE PHOSPHORYLASE

Sucrose phosphorylase is a bacterial transglucosidase that catalyzes the conversion of sucrose and phosphate into α-D-glucose-1-phosphate and D-fructose. The glucosylated Sucrose phosphorylase can also be hydrolyzed into α-D-glucose, or transfer the glucoyl to the hydroxyl group of the receptor, and then decomposed into new α-D-glucoside products. The enzymatic activity of base phosphorylase to substrate and product is weak[1].

  • CAS Number: 9074-06-0
  • MF: C21H15F3N2O2S
  • MW: 416.416
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 584.0±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 307.0±32.9 °C

(±)-Sigmoidin A

(±)-Sigmoidin A is an active compound. (±)-Sigmoidin A can be used for the research of various biochemical [1].

  • CAS Number: 176046-04-1
  • MF: C25H28O6
  • MW: 424.486
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 656.8±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 223.8±25.0 °C

α-Naphtholbenzein

α-Naphtholbenzein (p-Naphtolbenzein) is a dye. α-Naphtholbenzein can be used as a pH indicator. α-Naphtholbenzein has a visual transition from yellow (pH0-8.2) to turquoise (pH10). α-Naphtholbenzein is often used during sequential injection analysis technique done for acid-base titrations[1].

  • CAS Number: 145-50-6
  • MF: C27H18O2
  • MW: 374.431
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 578.6±50.0 °C at 760 mmHg
  • Melting Point: 230-235 °C(lit.)
  • Flash Point: 242.3±22.7 °C

Fmoc-Gly-Gly-OSU

Fmoc-Gly-Gly-OSu (Compound 98-6) is a dipeptide that can be used to synthesize ADC linker[1].

  • CAS Number: 114726-49-7
  • MF: C23H21N3O7
  • MW: 451.43
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

p38-α MAPK-IN-1

p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay.

  • CAS Number: 443913-15-3
  • MF: C27H35N5O3
  • MW: 477.6
  • Catalog: p38 MAPK
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isovalerylshikonin

Isovalerylshikonin (IVS) is a shikonin pigment is identified in the root epidermis of Echium italicum L[1].

  • CAS Number: 52387-14-1
  • MF: C21H24O6
  • MW: 372.41200
  • Catalog: Others
  • Density: 1.246g/cm3
  • Boiling Point: 570.1ºC at 760 mmHg
  • Melting Point: 107ºC
  • Flash Point: 198.6ºC

N-(tert-Butoxycarbonyl)-3-iodo-L-alanine Methyl Ester

Methyl (R)-2-((tert-butoxycarbonyl)amino)-3-iodopropanoate is an alanine derivative[1].

  • CAS Number: 93267-04-0
  • MF: C9H16INO4
  • MW: 329.132
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 356.5±32.0 °C at 760 mmHg
  • Melting Point: 50-52ºC(lit.)
  • Flash Point: 169.4±25.1 °C

Acetylcimigenol 3-O-alpha-L-arabinopyranside

Acetylshengmanol Arabinoside is isolated from Cimicifugae rhizoma.

  • CAS Number: 402513-88-6
  • MF: C37H58O10
  • MW: 662.850
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 748.5±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 225.6±26.4 °C

cis-Jasmone

Cis-Jasmone is a plant-derived natural product. Cis-Jasmone is constitutively released by many flowers and sometimes by leaves as an attractant for pollinators or as a chemical cue for host location by insect flower herbivores. Cis-Jasmone treatment of crop plants not only induces direct defense against herbivores, but also induces indirect defense by releasing VOCs that attract natural enemies[1].

  • CAS Number: 488-10-8
  • MF: C11H16O
  • MW: 164.244
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 264.2±0.0 °C at 760 mmHg
  • Melting Point: 203 - 205ºC
  • Flash Point: 107.2±0.0 °C

SBP-2

SBP-2 is a sulfite bioluminescent probe (SBP). The recognition of SBP-2 towards sulfite is based on the mechanism of a sulfite-mediated intramolecular cleavage reaction[1].

  • CAS Number: 2494035-92-4
  • MF: C17H16N2O5S2
  • MW: 392.45
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

6-O-Syringoylajugol

6-O-Syringoylajugol (compound 65) is a natural product that can be found in Verbacum spp[1].

  • CAS Number: 144049-72-9
  • MF: C24H32O13
  • MW: 528.50
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 762.5±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 256.4±26.4 °C

Pendimethalin

Pendimethalin is an herbicide that controls annual grasses and certain broadleaf weeds. Pendimethalin inhibits cell division and cell elongation[1].

  • CAS Number: 40487-42-1
  • MF: C13H19N3O4
  • MW: 281.308
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 421.0±45.0 °C at 760 mmHg
  • Melting Point: 56-57°C
  • Flash Point: 208.4±28.7 °C

Ac-VETD-AMC

Ac-VETD-AMC is a synthetic peptide substrate for caspase 8. Ac-VETD-AMC also has potential to assess functional activity of recombinant phytaspase[1].

  • CAS Number: 1135686-24-6
  • MF: C30H39N5O12
  • MW: 661.66
  • Catalog: Caspase
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

G-NGA2 N-Glycan

G-NGA2 N-Glycan is a N-Glycan, and can be used for labeling and modification of proteins.

  • CAS Number: 103584-68-5
  • MF: C56H94N4O41
  • MW:
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4'-Methoxypuerarin

4'-Methoxypuerarin (4'-O-Methylpuerarin), an isoflavone diglycoside, is isolated from Pueraria lobata[1].

  • CAS Number: 92117-94-7
  • MF: C22H22O9
  • MW: 430.405
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 661.7±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 232.2±25.0 °C

2,3-Dibromoacrylic acid

2,3-Dibromoacrylic acid is dibromo product based on acrylic acid. Acrylic acid is the simplest unsaturated carboxylic acid and can be used as a chemical intermediate.

  • CAS Number: 24767-86-0
  • MF: C3H2Br2O2
  • MW: 229.85500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MLS001006105

MLS001006105 is used for biological test against the protein target: lamin isoform A-delta10[1].

  • CAS Number: 455310-36-8
  • MF: C15H15N5O3S2
  • MW: 377.44
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Phe-Leu-Glu-Glu-Val-OH

Phe-Leu-Glu-Glu-Val is a peptide. Phe-Leu-Glu-Glu-Val can be used for the various biochemical studies[1].

  • CAS Number: 61037-79-4
  • MF: C30H45N5O10
  • MW: 635.706
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 1060.3±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 595.1±34.3 °C

3'-FLUORO-3'-DEOXYCYTIDINE

3′-Deoxy-3′-fluorocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 123402-20-0
  • MF: C9H12FN3O4
  • MW: 245.21
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: 1.82g/cm3
  • Boiling Point: 500.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 256.2ºC

Dodecyl glycinate

Dodecyl glycinate is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 13827-65-1
  • MF: C14H29NO2
  • MW: 243.38600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SW-034538

SW-034538 is a potent TAOK2 (Thousand-And-One Kinase 2; MAP3K17) inhibitor with IC50 of 300 nM, has cross-reactivity with respect to six of the 45 kinases (Raf1, GSK3β, JNK1, IRAK4, HGK and CDK2).

  • CAS Number: 412919-82-5
  • MF: C18H20N4O3S2
  • MW: 404.503
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A