(Rac)-BCN-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. (Rac)-BCN-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Pueroside B is an aromatic glycosidethat can be found in puerariae radix[1].
Coproporphyrin I tetramethyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
N-Methyl-N-phenylglycine is a Glycine (HY-Y0966) derivative[1].
L-Threitol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
TMAB is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Pinellic acid is a natural product that could be isolated from a medicinal plant Pinelliae tuber. Pinellic acid is an effective oral adjuvant for nasal influenza vaccine[1].
Perflubron(1-Bromoheptadecafluorooctane;Heptadecafluorooctyl bromide; Perfluorooctyl bromide) is a contrast medium for magnetic resonance imaging and sonography. Perflubron (1-Bromoheptadecafluorooctane;Heptadecafluorooctyl bromide; Perfluorooctyl bromide) can be emulsified with egg phospholipids (EYP) and shows exceptionally fast excretion characteristics[1][2].
3′-C-Methylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
2-Hydroxymethyltetrahydropyran is a volatile compound in Sambucus williamsii (SW) seed oil. SW seed oil has potential antioxidant activity[1].
NBD-X acid is a fluorescent probe for the study of fatty acids and sterols. NBD-X acid provides better yields for labelling biopolymers compared to NBD chloride and fluoride. The fluorescence spectrum of the NBD derivative is highly sensitive to the environment and the fluorescence intensity is significantly reduced in aqueous solutions[1].
Zorevunersen (STK-001) is an antisense oligonucleotide that is intended to increase the level of productive SCN1A mRNA and consequently increase the expression of the sodium channel Nav1.1 protein. Zorevunersen is used for the study of Dravet syndrome.
Mca-KKEDVV-Abu-CS-Abu-S-(NO2)F-KK-NH2 is a L-Lysine (HY-N0469) derivative[1].
2’-Deoxy-2’-fluoro-N3-(n-dodecyl)-beta-D-arabinouridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].
Glycylglycylalanine is a biologically active peptide.
Clarithromycin-d3is the deuterium labeledClarithromycin(HY-17508)[1]. Clarithromycin has a broad spectrum of antimicrobial activity. Clarithromycin inhibits the CYP3A4-catalyzed triazolam alpha-hydroxylation with the IC50 (Ki) value of 56 (43) μM[3]. Clarithromycin significantly inhibits the HERG potassium current[4].Clarithromycin affects the autophagic flux by impairing the signaling pathway linking hERG1 and PI3K[5].
2-Methylanisole-d3 is the deuterium labeled 2-Methylanisole[1]. 2-Methylanisole is a monomethoxybenzene and acts as an intermediate for the preparation of compounds with methylhydroquinone core[2].
Tianeptine metabolite MC5 sodium salt is a major active metabolite of tianeptine. Tianeptine and MC5 metabolite are eliminated with bile as glucuronide and glutamine conjugates[1].
(+)-5,7,4'-Trimethoxyafzelechin is a derivative of (+)-Afzelechin HY-N2821. (+)-Afzelechin is an α-glucosidase activity inhibitor. (+)-Afzelechin can be isolated from rhizomes of Bergenia ligulata[1].
N1,N1'-(Propane-1,3-diyl)bis(propane-1,3-diamine)-d12 is the deuterium labeled N1,N1'-(Propane-1,3-diyl)bis(propane-1,3-diamine)[1].
Progranulin modulator-1 (Compound 60) is an orally active enhancer of progranulin (PGRN) secretion. Progranulin modulator-1 enhances the potency of BV-2 cell to increase PGRN levels, has inhibitory effect on hERG and Low cytotoxicity, the PGRN EC50 and hERG IC50 were 83 and 3100 nM, respectively[1].
Boc-Asp-OMe is an aspartic acid derivative[1].
Tetrapeptide-4 is a peptide ingredient commonly used in skin care products to reduce wrinkles, strengthen collagen, elastin and fibronectin, and possess powerful anti-aging properties[1].
Pep-1 (uncapped) is a cell-penetrating peptide.
L-Octanoylcarnitine is the physiologically active form of octanoylcarnitine.
Kaempferol 3-O-arabinoside is an antioxidant flavonoids isolated from ethyl acetate fraction (EAF) obtained from the leaves of Nectandra hihua. Kaempferol 3-O-arabinoside has good antioxidant capacity[1].
Coumarin-C2-TCO 是 Coumarin (HY-N0709) 的染料衍生物。Coumarin-C2-TCO 可利用自身的 TCO 基团与带 Tetrazine 基团的分子发生逆电子需求 Diels-Alder 反应 (iEDDA)。
Apelin-12 is one of the most potent C-terminal fragments of the polypeptide that possesses a high affinity to orphan receptor APJ receptor. Apelin-12 is involved in the regulation of body fluid homeostasis and in the central control of feeding. Apelin-12 blocks HIV-1 entry through APJ receptor. Apelin-12 exerts neuroprotective effect[1][2][3].
Undecylamine-d23 is the deuterium labeled Undecylamine[1].
N-Acetyl-R-leucine is an amino protecting group N-substituted chiral amino acid[1].