2641013-11-6
2641013-11-6 structure
- Name: Progranulin modulator-1
- Chemical Name: Progranulin modulator-1
- CAS Number: 2641013-11-6
- Molecular Formula: C21H21F2N3O
- Molecular Weight: 369.41
- Catalog: Research Areas Others
- Create Date: 2023-11-11 21:24:39
- Modify Date: 2025-08-25 09:57:21
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Progranulin modulator-1 (Compound 60) is an orally active enhancer of progranulin (PGRN) secretion. Progranulin modulator-1 enhances the potency of BV-2 cell to increase PGRN levels, has inhibitory effect on hERG and Low cytotoxicity, the PGRN EC50 and hERG IC50 were 83 and 3100 nM, respectively[1].
| Name | Progranulin modulator-1 |
|---|
| Description | Progranulin modulator-1 (Compound 60) is an orally active enhancer of progranulin (PGRN) secretion. Progranulin modulator-1 enhances the potency of BV-2 cell to increase PGRN levels, has inhibitory effect on hERG and Low cytotoxicity, the PGRN EC50 and hERG IC50 were 83 and 3100 nM, respectively[1]. |
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| Related Catalog | |
| Target |
EC50: 83 nM (PGRN); IC50: 3100 nM (hERG) |
| References |
| Molecular Formula | C21H21F2N3O |
|---|---|
| Molecular Weight | 369.41 |