2415330-04-8

2415330-04-8 structure

Name: Zorevunersen
Chemical Name: Zorevunersen
CAS Number: 2415330-04-8
Molecular Formula: C₂₀₄H₂₆₃N₆₃O₁₁₄P₂₀S₂₀
Molecular Weight: 6682.39
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
Create Date: 2023-01-24 17:53:44
Modify Date: 2024-01-31 11:32:20
Zorevunersen (STK-001) is an antisense oligonucleotide that is intended to increase the level of productive SCN1A mRNA and consequently increase the expression of the sodium channel Nav1.1 protein. Zorevunersen is used for the study of Dravet syndrome.

Name	Zorevunersen

Description	Zorevunersen (STK-001) is an antisense oligonucleotide that is intended to increase the level of productive SCN1A mRNA and consequently increase the expression of the sodium channel Nav1.1 protein. Zorevunersen is used for the study of Dravet syndrome.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Others
Target	Nav1.1
References	[1]. Wengert ER, Wagley PK, Strohm SM, et al. Targeted Augmentation of Nuclear Gene Output (TANGO) of Scn1a rescues parvalbumin interneuron excitability and reduces seizures in a mouse model of Dravet Syndrome. Brain Res. 2022;1775:147743. [2]. Bialer M, Johannessen SI, Koepp MJ, et al. Progress report on new antiepileptic drugs: A summary of the Sixteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVI): II. Drugs in more advanced clinical development. Epilepsia. 2022;63(11):2883-2910.

Molecular Formula	C₂₀₄H₂₆₃N₆₃O₁₁₄P₂₀S₂₀
Molecular Weight	6682.39