Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Hrk BH3

Hrk BH3 is a biological active peptide. (BH3 domain of Hrk)

  • CAS Number: 1644272-97-8
  • MF: C99H160N30O31
  • MW: 2266.51
  • Catalog: Bcl-2 Family
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SYBR Green II

SYBR Green II is a fluorescent nucleic acid dye that mainly binds single-stranded nucleotides. SYBR Green II is sensitive to oligonucleotides or larger nucleic acid polymers in a variety of cells and gels. SYBR Green II can be used to study cell structure, membrane integrity or function, and cell cycle distribution. Wavelength 484/515 nm[1].

  • CAS Number: 195199-08-7
  • MF: C28H28IN3OS
  • MW: 581.51
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Azedarachol

Azedarachol possesses antifeedant activity[1].

  • CAS Number: 99305-11-0
  • MF: C25H40O5
  • MW: 420.58
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Asn(Trt)-Thr(psi Me,Mepro)-OH

Fmoc-Asn(Trt)-Thr(psi(Me,Me)pro)-OH is a dipeptide.

  • CAS Number: 957780-59-5
  • MF: C45H43N3O7
  • MW: 737.839
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 962.8±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 536.1±34.3 °C

6-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YLAMINEHYDROCHLORIDE

2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-2-(4-methoxyphenyl)aceticacid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 868260-17-7
  • MF: C18H26N2O5
  • MW: 350.40900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4H-1-Benzopyran-4-one, 2-(4-(beta-D-glucopyranosyloxy)phenyl)-2,3-dihy dro-5,7-dihydroxy-, (2S)-

Choerospondin is a flavanone isolated from the bark of Choerospondias axillaris[1].

  • CAS Number: 81202-36-0
  • MF: C21H22O10
  • MW: 434.39300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

kopsininic acid

Kopsininic acid is a natural product derived from Kopsia hainanensis. Kopsininic acid can be used in the research of rheumatoid arthritis, pharyngitis, tonsillitis and edema[1].

  • CAS Number: 7222-19-7
  • MF: C20H24N2O2
  • MW: 324.42
  • Catalog: Others
  • Density: 1.37±0.1 g/cm3(Predicted)
  • Boiling Point: 551.8±50.0 °C(Predicted)
  • Melting Point: 209-211 °C
  • Flash Point: N/A

7-Hydroxycoumarinyl arachidonate

7-Hydroxycoumarinyl arachidonate (7-HCA) is a fluorogenic substrate of cytosolic phospholipase A2 (PLA2). 7-Hydroxycoumarinyl arachidonate is also a fluorogenic substrate for monoacylglycerol lipase (MAGL). MAGL protein catalyzes the hydrolysis of 7-Hydroxycoumarinyl arachidonat to generate Arachidonic acid (AA) and the highly fluorescent 7-hydroxyl coumarin (7-HC; HY-N0573). Release of 7-HC can be measured using a fluorometer[1][2][3].

  • CAS Number: 161180-11-6
  • MF: C29H36O4
  • MW: 448.594
  • Catalog: MAGL
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 584.7±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 289.4±28.5 °C

4-METHYLCATECHOL-D8

4-Methylcatechol-d8 is the deuterium labeled 4-Methylcatechol[1]. 4-Methylcatechol, a metabolite of p-toluate, is a substrate as well as a suicide inhibitor of Catechol 2,3-Dioxygenase[2].

  • CAS Number: 1219803-18-5
  • MF: C7D8O2
  • MW: 132.186514224
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

sialylglycopeptide

Sialylglycopeptide is a complex N-glycan, bearing a short peptide fragment. Sialylglycopeptide, as a starting material for the semi-synthesis of N-glycans, can be used for various researches[1].

  • CAS Number: 189035-43-6
  • MF: C115H187N15O68
  • MW: 2867.775
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Chlorobenzoic acid-d4

4-Chlorobenzoic acid-d4 is the deuterium labeled 4-Chlorobenzoic acid-d4[1].

  • CAS Number: 85577-25-9
  • MF: C7HClD4O2
  • MW: 160.59100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Gadopentetate dimeglumine

Gadopentetate dimeglumine (SH-L-451A) is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on the MRI.

  • CAS Number: 86050-77-3
  • MF: C28H54GdN5O20
  • MW: 938.000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Mudanpioside C

Mudanpioside C is a monoteepenoid isolated from Paeonia lactiflora Pall .

  • CAS Number: 172760-03-1
  • MF: C30H32O13
  • MW: 600.567
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 789.1±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 258.6±26.4 °C

Fmoc-VAP-MMAE

Fmoc-VAP-MMAE is a drug-linker conjugates for ADC. Fmoc-VAP-MMAE consists of an ADC linker and a tubulin inhibitor MMAE (HY-15162), with a protective Fmoc group[1].

  • CAS Number: 1912408-91-3
  • MF: C70H98N8O13
  • MW: 1259.57
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Humantenidine

Humantenidine, an indole alkaloid, is isolated from Gelsemium sempervirens.

  • CAS Number: 114027-39-3
  • MF: C19H22N2O4
  • MW: 342.389
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 513.3±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 264.2±32.9 °C

Lappaconitine

Lappaconitine, isolated from Aconitum sinomontanum Nakai, was characterized as analgesic principle.IC50 value:Target:In vitro: In vivo: Lappaconitine was characterized as analgesic principle by our laboratory. The results suggest that lappaconitine can produce analgesia, possibly through a decrease in cellular calcium availability and PAG may be involved in the Ca2+ antagonistic effect on lappaconitine analgesia [1]. Changes in lappaconitine levels in blood, brain and spinal cord following subcutaneous (s.c.) injection were correlated with the analgesic activity at intervals up to 90 minutes after injection. The equianalgesic doses of lappaconitine (ED50 by the s.c. route and additive ED50 by the i.c.v. plus i.t. route) gave closely similar concentrations of the drug in brain and spinal cord. These results indicate that a simultaneous action of lappaconitine on supraspinal and spinal sites is likely to be important for the analgesia produced by systemically administered lappaconitine [2].

  • CAS Number: 32854-75-4
  • MF: C32H44N2O8
  • MW: 584.700
  • Catalog: P2X Receptor
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 720.7±60.0 °C at 760 mmHg
  • Melting Point: 217-218ºC
  • Flash Point: 389.7±32.9 °C

4’-C-Methyl-2-thiouridine

4’-C-Methyl-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 2305415-74-9
  • MF: C10H14N2O5S
  • MW: 274.29
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-ethylmaleimide

N-Ethylmaleimide (NEM) is a cysteine protease inhibitor[1]. N-ethylmaleimide specific inhibits phosphate transport in mitochondria[2].

  • CAS Number: 128-53-0
  • MF: C6H7NO2
  • MW: 125.13
  • Catalog: Cathepsin
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 210.0±9.0 °C at 760 mmHg
  • Melting Point: 43-46 °C(lit.)
  • Flash Point: 73.3±0.0 °C

(E)-2-(3-Hydroxy-4-methoxyphenyl)ethyl 4-[3-(4-hydroxy-3-methoxyphenyl)-2-propenoate] beta-D-glucopyranoside

Desrhamnosylmartynosideis extracted from the root of Scutellaria prostrata. Desrhamnosylmartynoside has absorption bands assignable to hydroxyl,α,β-unsanturate carbonyl groups[1].

  • CAS Number: 136055-64-6
  • MF: C25H30O11
  • MW: 506.50
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 734.6±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 246.2±26.4 °C

Arabinofuranosidase, α-l-

α-L-Arabinofuranosidase is a glycosidic hydrolase. α-L-Arabinofuranosidase hydrolyse the nonreducing termini of the a-l-arabinofuranosyl residues as side chains of arabinoxylan, arabinan and arabinogalactan[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Floramanoside C

Floramanoside C shows 2,2-diphenyl-1-picrylhydrazyl scavenging and aldose reductase inhibitory activities[1].

  • CAS Number: 1403981-95-2
  • MF: C21H18O15
  • MW: 510.36
  • Catalog: Aldose Reductase
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

confusarin

Confusarin (compound 12) is a phenanthrene compound that was isolated from F. fimbriata for the first time[1].

  • CAS Number: 108909-02-0
  • MF: C17H16O5
  • MW: 300.30600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

biotin-Bradykinin

biotin-Bradykinin is a biological active peptide. (Biotin labeled HY-P0206)

  • CAS Number: 477319-71-4
  • MF: C60H87N17O13S
  • MW: 1286.50
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-TIGLOYLGLYCINE

(E)-2-(2-Methylbut-2-enamido)acetic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 35842-45-6
  • MF: C7H11NO3
  • MW: 157.16700
  • Catalog: Others
  • Density: 1.138g/cm3
  • Boiling Point: 394.9ºC at 760 mmHg
  • Melting Point: 86ºC
  • Flash Point: 192.6ºC

H-Phe-ObzlTos

H-Phe-OBzl.TosOH is a phenylalanine derivative[1].

  • CAS Number: 1738-78-9
  • MF: C23H25NO5S
  • MW: 427.513
  • Catalog: Others
  • Density: 1.142g/cm3
  • Boiling Point: 382.8ºC at 760mmHg
  • Melting Point: 168 °C
  • Flash Point: 220.3ºC

EphB3-IN-1

EphB3-IN-1 is the first potent, selective inhibitor of EphB3 that exhibits inhibiting EphB3 autophosphorylation in cells with IC50 of 3 nM; causes foremost inhibition of EphB3 in a panel of 98 kinases, except for RIPK2 and PHKG2; abolishes the EphB3 autophosphorylation at Y608 and Y614 at 100 nM.

  • CAS Number: 1980036-18-7
  • MF: C16H12Cl2N4O2
  • MW: 363.198
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

stearyl behenate

Stearyl behenate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 24271-12-3
  • MF: C40H80O2
  • MW: 593.06200
  • Catalog: Others
  • Density: 0.856g/cm3
  • Boiling Point: 589.1ºC at 760 mmHg
  • Melting Point: 66.6 °C
  • Flash Point: 322.8ºC

Tetraethylammonium 4-methylbenzenesulfonate

Tetraethylammonium 4-methylbenzenesulfonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 733-44-8
  • MF: C15H27NO3S
  • MW: 301.445
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 110-114 °C(lit.)
  • Flash Point: N/A

Thymolphthalexon

Thymolphthalexon is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 62698-55-9
  • MF: C38H40N2Na4O12
  • MW: 808.68900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 886.7ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 490ºC

3,5-dichloro-2-hydroxybenzenesulphonic acid

3,5-Dichloro-2-hydroxybenzenesulfonic acid is used in conjunction with Ampyrone (HY-B1398) (4-AAP) and hydrogen peroxide (H2O2) for chromogenic quantification of peroxidase in coupled enzymatic reactions. 3,5-Dichloro-2-hydroxybenzenesulfonic acid is used to measure hydrogen peroxide production in conjunction with peroxidase[1].

  • CAS Number: 26281-43-6
  • MF: C6H4Cl2O4S
  • MW: 243.06500
  • Catalog: Others
  • Density: 1.806g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A