1980036-18-7
1980036-18-7 structure
- Name: EphB3-IN-1
- Chemical Name: EphB3-IN-1
- CAS Number: 1980036-18-7
- Molecular Formula: C16H12Cl2N4O2
- Molecular Weight: 363.198
- Catalog: Research Areas Others
- Create Date: 2020-01-11 16:24:50
- Modify Date: 2024-10-05 16:56:48
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EphB3-IN-1 is the first potent, selective inhibitor of EphB3 that exhibits inhibiting EphB3 autophosphorylation in cells with IC50 of 3 nM; causes foremost inhibition of EphB3 in a panel of 98 kinases, except for RIPK2 and PHKG2; abolishes the EphB3 autophosphorylation at Y608 and Y614 at 100 nM.
| Name | EphB3-IN-1 |
|---|
| Description | EphB3-IN-1 is the first potent, selective inhibitor of EphB3 that exhibits inhibiting EphB3 autophosphorylation in cells with IC50 of 3 nM; causes foremost inhibition of EphB3 in a panel of 98 kinases, except for RIPK2 and PHKG2; abolishes the EphB3 autophosphorylation at Y608 and Y614 at 100 nM. |
|---|---|
| References | References 1. Kung A, et al. J Am Chem Soc. 2016 Aug 24;138(33):10554-60. View Related Products by Target Ephrin Receptor |
| Molecular Formula | C16H12Cl2N4O2 |
|---|---|
| Molecular Weight | 363.198 |