Decarboxy Moxifloxacin (compound 8) is a decarboxylated compound of Moxifloxacin. Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia[1].
DL-Aspartic acid dimethyl ester hydrochloride is an aspartic acid derivative[1].
Boc-L-Ile-OH is an isoleucine derivative[1].
Tetramethylammonium hydrogensulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Aspartate aminotransferase (AST) is a transaminase enzyme, is often used in biochemical studies. Aspartate aminotransferase catalyzes aspartate and alpha-ketoglutarate converts to oxaloacetate and glutamate. Aspartate aminotransferase can be found in cerebrospinal fluid, exudates, and transudates[1].
Wnt/β-catenin agonist 1 (compound 3f) is a Wnt/β-catenin signalling pathway agonist, with an EC50 of 0.27 μM[1].
L-Xylose-5-13C is the 13C labeled L-Xylose. L-Xylose (L-(-)-Xylose) is the levo-isomer of Xylose. Xylose is classified as a monosaccharide of the aldopentose type[1][2].
3,4-Dichlorobiphenyl-d5 is the deuterium labeled 3,4-Dichlorobiphenyl[1].
D-Gulose-13C is the 13C labeled (2R,3R,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal[1].
Calpurbatug is an immunoglobulin G1 antibody. Calpurbatug has activity with anti-bacterial DNA-binding protein DNABII family and anti-human monoclonal TRL1068 γ1-chain[1].
Boldenone Cypionate is an androgenic anabolic steroid.
Benzyl (tert-butoxycarbonyl)-L-tyrosinate is a tyrosine derivative[1].
5a-Cholest-8-en-3b-ol-d7 is deuterium labeled 5a-Cholest-8-en-3b-ol.
Octadeca-9,12-dienamide is an endogenous lipid[1].
Cocoa butter can be used as an excipient, such as lubricants, suppository bases. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].
FG-2216 is a potent HIF-prolyl hydroxylase inhibitor with IC50 of 3.9 uM for PDH2 enzyme; orally bioavailable and induced significant and reversible Epo induction in vivo.IC50 value: 3.9 uM [1]Target: PDH inhibitorFG-2216 was orally bioavailable and induced significant and reversible Epo induction in vivo (82- to 309-fold at 60 mg/kg). Chronic oral dosing in male rhesus macaques was well tolerated, significantly increased erythropoiesis, and prevented anemia induced by weekly phlebotomy. Furthermore, modest increases in HbF-containing red cells and reticulocytes were demonstrated by flow cytometry, though significant increases in HbF were not demonstrated by high-pressure liquid chromatography (HPLC) [2].
CY3-SE is a reactive dye for the labeling of amino-groups in biomolecules. CY3-SE is ideal for the labeling of soluble proteins, peptides, and oligonucleotides/DNA. Excitation (nm):555, Emission (nm): 570.
Baptifoline is an alkaloid isolated from the rhizome of Caulophyllum thalictroides[1].
Parishin C, a parishin derivative isolated from Gastrodia elata, may have antioxidant property[1].
Cyantraniliprole D3 is the deuterium labeled Cyantraniliprole, which is an insecticide of the ryanoid class.
3-Oxo-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone is a tetranortirucallane-type triterpenoid that can be isolated from Dysoxylum lenticellatum. 3-Oxo-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone has vasodilative effect with diastolic degree of 43.5% at 10 渭g/mL[1].
Piperidin-4-ol-d4 is the deuterium labeled Piperidin-4-ol[1].
Oleoyl proline is a novel N-acyl amine compound[1].
(R)-2,3-Dihydroxypropanal-d2 is the deuterium labeled (R)-2,3-Dihydroxypropanal[1].
3,3'-Azanediyldipropionic acid-d8 is the deuterium labeled 3,3'-Azanediyldipropionic acid[1].
D-Val-Leu-Arg-pNA (acetate) is the acetate form of D-Pro-Phe-Arg-p-nitroanilide (pNa). D-Pro-Phe-Arg-p-nitroanilide (pNa) is the substrate for kallikrein and can be used to assay the activity of kallikrein[1].
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N-methyl-D-leucine is a leucine derivative[1].
Epelsiban (GSK 557296) is a potent, selective and orally bioavailable oxytocin receptor antagonist, with a pKi of 9.9 for human oxytocin receptor.
AP-C6 is a potent inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 6.5. AP-C6 concentration-dependently inhibits human cGKII activity in vitro. AP-C6 potentiate cAMP signaling by PDE inhibition[1].
Phytochelatin 3 (PC 3) is the small metal chelating peptide that can be used for chelating heavy metals[1].